{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:10:20Z","timestamp":1778227820415,"version":"3.51.4"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NHS E Cancer Programme"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>During the COVID-19 pandemic the National Health Service introduced colon capsule endoscopy (CCE) as an alternative to colonoscopy in patients awaiting 3-year post-polypectomy surveillance. We determined the safety, diagnostic accuracy, and utility of CCE in this clinical setting.<\/jats:p>\n                  <jats:p>Consenting patients awaiting 3-year post-polypectomy surveillance underwent CCE or colonoscopy. For those having CCE, risk-based guidance was developed directing to: 1) immediate colorectal endoscopic intervention; 2) deferred intervention; or 3) discharge. The safety, comparative and paired diagnostic accuracy, and colonoscopy capacity spared by CCE were determined.<\/jats:p>\n                  <jats:p>There were 464 CCE and 78 colonoscopy patients recruited. CCE patients were younger (mean 62 years versus 68 years). CCE was safely tolerated in 99% of patients. More \u2265 10 mm and 6- to 9-mm polyps were detected in the CCE cohort than the colonoscopy comparator cohort. This was on an intention to investigate basis and in those who had complete and adequately prepared examinations. Two hundred and five CCE patients had an urgent colonoscopy or flexible sigmoidoscopy and their paired findings were matched. Per patient sensitivities for \u2265 10 mm and 6- to 9-mm polyps were 92% and 90%, respectively. Two-thirds of patients entered a modified management pathway after CCE with 25% being discharged and 27% having a procedure deferral for up to 3 years. CCE completion and bowel preparation adequacy rates were 78% and 73% respectively. No colorectal cancer was detected.<\/jats:p>\n                  <jats:p>CCE is a safe diagnostic of colorectal polyps. In surveillance, its \"filter function\" complements existing colorectal diagnostic services by providing capacity and choice.<\/jats:p>","DOI":"10.1055\/a-2779-1774","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T23:35:58Z","timestamp":1768347358000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Multicenter study of colon capsule endoscopy in post-polypectomy surveillance"],"prefix":"10.1055","volume":"14","author":[{"given":"James","family":"Turvill","sequence":"additional","affiliation":[{"name":"Gastroenterology, York and Scarborough Teaching Hospitals NHS Foundation Trust, York, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Haritakis","sequence":"additional","affiliation":[{"name":"Research and Innovation, York and Scarborough Teaching Hospitals NHS Foundation Trust, York, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Pygall","sequence":"additional","affiliation":[{"name":"Improvement Delivery, NHS England and NHS Improvement East of England, Welwyn Garden City, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Bryant","sequence":"additional","affiliation":[{"name":"NHS Cancer Programme, NHS England, Redditch, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harriet","family":"Cox","sequence":"additional","affiliation":[{"name":"Research and Innovation, York and Scarborough Teaching Hospitals NHS Foundation Trust, York, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Forshaw","sequence":"additional","affiliation":[{"name":"Research and Innovation, York and Scarborough Teaching Hospitals NHS Foundation Trust, York, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crispin","family":"Musicha","sequence":"additional","affiliation":[{"name":"Medical Statistics Group, Plymouth University, Plymouth, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Allgar","sequence":"additional","affiliation":[{"name":"Medical Statistics Group, Plymouth University, Plymouth, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Logan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, King's College London, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0985-3643","authenticated-orcid":false,"given":"Mark","family":"McAlindon","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology and Hepatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/S2468-1253(21)00058-3","article-title":"Predicting endoscopic activity recovery in England after COVID-19: a national analysis","volume":"6","author":"KMA Ho","year":"2021","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.17560","article-title":"Diagnostic accuracy for per-patient polyp detection of second-generation capsule 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cohort study","volume":"18","author":"W Atkin","year":"2017","journal-title":"Lancet Oncol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1136\/gutjnl-2019-319858","article-title":"BSG\/ACPGBI\/PHE post-polypectomy and post-colorectal cancer resection surveillance guidelines","volume":"69","author":"MD Rutter","year":"2020","journal-title":"Gut"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1055\/s-0031-1291717","article-title":"Colon capsule endoscopy: ESGE Guideline","volume":"44","author":"C Spada","year":"2012","journal-title":"Endoscopy"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1055\/a-1185-3109","article-title":"Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline \u2013 Update 2020","volume":"52","author":"C Hassan","year":"2020","journal-title":"Endoscopy"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.gie.2008.05.057","article-title":"The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research","volume":"69","author":"EJ Lai","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.gie.2020.05.062","article-title":"Colon Capsule CLEansing Assessment and Report (CC-CLEAR): a new approach for evaluation of the quality of bowel preparation in capsule colonoscopy","volume":"93","author":"R de Sousa Magalh\u00e3es","year":"2021","journal-title":"Gastrointest Endosc"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1136\/gutjnl-2016-312044","article-title":"UK key performance indicators and quality assurance standards for colonoscopy","volume":"65","author":"CJ 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a mixed methods study","volume":"58","author":"MK Thygesen","year":"2019","journal-title":"Acta Oncologica"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2779-1774.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T07:17:51Z","timestamp":1778224671000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2779-1774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,13]]},"references-count":31,"journal-issue":{"issue":"CP","published-online":{"date-parts":[[2026,1,13]]},"published-print":{"date-parts":[[2026]]}},"alternative-id":["a27791774"],"URL":"https:\/\/doi.org\/10.1055\/a-2779-1774","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,13]]}}}