{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T21:29:11Z","timestamp":1784150951806,"version":"3.55.0"},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T00:00:00Z","timestamp":1767484800000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J Pediatr Surg Rep."],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Indocyanine green fluorescence (ICG-F)-guided surgery has, in recent years, optimized the precision and safety of surgical procedures.<\/jats:p>\n                  <jats:p>Although its applications are increasingly widespread, in most cases, the dye is administered intravenously.<\/jats:p>\n                  <jats:p>We present a case of inhaled indocyanine green use for the identification and resection of pulmonary metastatic nodules.<\/jats:p>\n                  <jats:p>A 12-year-old female patient with a history of sternal Ewing sarcoma with bone and pulmonary metastases was treated with chemotherapy, proton therapy, partial sternal and costal cartilage resection, and reconstruction with mesh and absorbable plates.<\/jats:p>\n                  <jats:p>She later developed pulmonary relapse, with two subpleural metastases identified in segments 6 and 9 of the right lung. After initiating chemotherapy, thoracoscopic surgery was planned to resect the nodules.<\/jats:p>\n                  <jats:p>Before surgery, nebulization of indocyanine green was performed via an endotracheal tube at 0.2\u2009mg\/kg using an inhalation chamber for 5\u2009minutes at 6 liters per minute.<\/jats:p>\n                  <jats:p>During surgery, fluorescence was observed in the insufflated lung parenchyma, allowing for clear differentiation of metastatic nodules from peripheral fibrotic or inflammatory tissue and enabling a safe wedge resection of both lesions.<\/jats:p>\n                  <jats:p>The postoperative period was uneventful, and the patient is currently completing postoperative chemotherapy cycles.<\/jats:p>","DOI":"10.1055\/a-2780-3527","type":"journal-article","created":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T23:32:16Z","timestamp":1767569536000},"page":"e1-e4","source":"Crossref","is-referenced-by-count":1,"title":["Inhaled Indocyanine Green Negative-contrast Fluorescence-guided Surgery for Pulmonary Metastasectomy"],"prefix":"10.1055","volume":"14","author":[{"given":"\u00c1ngel Javier Gallego","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Virgen de las Nieves, Granada, Andaluc\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Andr\u00e9s Moreno","family":"Delgado","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Virgen de las Nieves, Granada, Andaluc\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Francisco Navarro","family":"Pardo","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Virgen de las Nieves, Granada, Andaluc\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elo\u00edsa Diaz","family":"Moreno","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Virgen de las Nieves, Granada, Andaluc\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Palomares","family":"Garz\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Virgen de las Nieves, Granada, Andaluc\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Fernandez-Valad\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Hospital Universitario Virgen de las Nieves, Granada, Andaluc\u00eda, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,1,24]]},"reference":[{"issue":"11","key":"ref1","doi-asserted-by":"crossref","first-page":"161657","DOI":"10.1016\/j.jpedsurg.2024.07.042","article-title":"Clinical consensus statement on the use of indocyanine green fluorescence-guided surgery in pediatric patients","volume":"59","author":"P O Szavay","year":"2024","journal-title":"J Pediatr Surg"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"162063","DOI":"10.1016\/j.jpedsurg.2024.162063","article-title":"Precise thoracoscopic pneumonectomy using fluorescence imaging after aerosolized indocyanine green inhalation: a novel strategy for treating congenital pulmonary airway malformation","volume":"60","author":"T Zhu","year":"2025","journal-title":"J Pediatr Surg"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1016\/j.asjsur.2024.11.052","article-title":"Thoracoscopic anatomical lesion resection by fluorescence imaging on congenital lung malformation","volume":"48","author":"T He","year":"2025","journal-title":"Asian J Surg"},{"issue":"08","key":"ref4","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1001\/jamasurg.2020.1314","article-title":"Evaluation of intraoperative near-infrared fluorescence visualization of the lung tumor margin with indocyanine green inhalation","volume":"155","author":"Y H Quan","year":"2020","journal-title":"JAMA Surg"},{"issue":"09","key":"ref5","doi-asserted-by":"crossref","first-page":"5912","DOI":"10.1245\/s10434-023-13753-4","article-title":"Efficacy of near-infrared fluorescence video-assisted thoracoscopic surgery for small pulmonary nodule resection with indocyanine green inhalation: a randomized clinical trial","volume":"30","author":"K Wang","year":"2023","journal-title":"Ann Surg Oncol"}],"container-title":["European Journal of Pediatric Surgery Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2780-3527.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:39:29Z","timestamp":1769819969000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2780-3527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":5,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2026,1,24]]},"published-print":{"date-parts":[[2026,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2780-3527","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2194-7619","2194-7627"],"issn-type":[{"value":"2194-7619","type":"print"},{"value":"2194-7627","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1,4]]},"published":{"date-parts":[[2026,1]]}}}