{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:10:34Z","timestamp":1778227834939,"version":"3.51.4"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Endoscopic full-thickness resection (EFTR) can be used to treat recurrent or residual colorectal adenomas. No data are available on treatment of recurrences after EFTR, especially on feasibility and safety of repeat EFTR (re-EFTR)<\/jats:p>\n                  <jats:p>This single-center retrospective study included patients who underwent device-assisted non-exposed re-EFTR in the colorectum. Technical success, adverse events (AEs), and recurrences were analyzed and compared to patients with primary EFTR.<\/jats:p>\n                  <jats:p>Twenty-seven patients who underwent re-EFTR were included. Median age was 75 years (range: 54\u201385 years) and nine patients were female (33.3%). The indication for re-EFTR was recurrent adenoma in 24 patients (88.9%) and most lesions were in the right-sided colon (n = 22; 81.5%). Technical success was achieved in 22 patients (81.5%). Reasons for failure were failure to reach the lesion in one case and inability to fully mobilize the lesion into the cap in four cases. Follow-up after 2 to 6 months revealed recurrent lesion in four of 24 cases (16.7%) and four more occurred during further follow-up. Surgery was necessary in two cases. AEs occurred in two cases (7.4%). Comparison with primary EFTR showed a trend toward lower technical success (81.5% vs. 100.0%, P = .051), but no differences in recurrence or AEs.<\/jats:p>\n                  <jats:p>Repeat EFTR for recurrence after a previous EFTR is feasible in most patients and only a few patients require surgical resection. The rate of recurrence might be higher than that after primary EFTR, yet there are no differences in AEs.<\/jats:p>","DOI":"10.1055\/a-2781-6514","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T01:17:50Z","timestamp":1770686270000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Feasibility of repeat non-exposed endoscopic full-thickness resection of recurrent or residual colonic adenoma after previous full-thickness resection"],"prefix":"10.1055","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9660-1323","authenticated-orcid":false,"given":"Andreas","family":"Wannhoff","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology, Haemato-Oncology, Diabetology, and Infectious Diseases, Ludwigsburg Hospital, Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Takhgiriev","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology, Haemato-Oncology, Diabetology, and Infectious Diseases, Ludwigsburg Hospital, Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remy","family":"Hosari","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology, Haemato-Oncology, Diabetology, and Infectious Diseases, Ludwigsburg Hospital, Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Hubbes","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology, Haemato-Oncology, Diabetology, and Infectious Diseases, Ludwigsburg Hospital, Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karel","family":"Caca","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology, Haemato-Oncology, Diabetology, and Infectious Diseases, Ludwigsburg Hospital, Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1136\/gutjnl-2013-305516","article-title":"Long-term adenoma recurrence following wide-field endoscopic mucosal resection (WF-EMR) for advanced colonic mucosal neoplasia is infrequent: results and risk factors in 1000 cases from the Australian Colonic EMR (ACE) study","volume":"64","author":"A Moss","year":"2015","journal-title":"Gut"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.gie.2016.11.027","article-title":"Adenoma recurrence after piecemeal colonic EMR is 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resection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2024","volume":"56","author":"M Ferlitsch","year":"2024","journal-title":"Endoscopy"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"29","DOI":"10.7326\/M23-1812","article-title":"Endoscopic en bloc versus piecemeal resection of large nonpedunculated colonic adenomas: A randomized comparative trial","volume":"177","author":"J Jacques","year":"2024","journal-title":"Ann Intern Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1055\/s-0034-1391781","article-title":"Endoscopic full-thickness resection in the colorectum with a novel over-the-scope device: first experience","volume":"47","author":"A Schmidt","year":"2015","journal-title":"Endoscopy"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1136\/gutjnl-2016-313677","article-title":"Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in 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meta-analysis","volume":"36","author":"Z Nabi","year":"2024","journal-title":"Dig Endosc"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.14309\/ajg.0000000000000795","article-title":"Efficacy and safety of endoscopic full-thickness resection in the colorectum: Results from the German Colonic FTRD Registry","volume":"115","author":"B Meier","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.gie.2023.03.020","article-title":"Efficacy and safety of combined EMR and endoscopic full-thickness resection (hybrid EFTR) for large nonlifting colorectal adenomas","volume":"98","author":"B Meier","year":"2023","journal-title":"Gastrointest Endosc"},{"key":"ref14","first-page":"476","article-title":"Hybrid endoscopic approaches for complex colorectal polyps with a non-lifting sign: the Greek experience","volume":"37","author":"G Tribonias","year":"2024","journal-title":"Ann 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Mahadev","year":"2021","journal-title":"Gastrointest Endosc"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1080\/00365521.2021.1933583","article-title":"Hybrid resection of large colorectal adenomas combining EMR and FTRD","volume":"56","author":"M Bauermeister","year":"2021","journal-title":"Scand J Gastroenterol"}],"container-title":["Endoscopy International 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