{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T04:57:53Z","timestamp":1770785873786,"version":"3.50.0"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To evaluate fertility and obstetric and clinical outcomes following uterine artery embolization (UAE) for pregnancy-related symptomatic uterine arteriovenous malformations (AVMs).<\/jats:p>\n                  <jats:p>A retrospective case analysis was conducted at a single tertiary care center and included women diagnosed with symptomatic post-pregnancy uterine AVMs treated between January 2000 and April 2023. Clinical data, management strategies, and follow-up outcomes were extracted from institutional records. A follow-up phone survey was conducted to assess fertility and obstetric outcomes.<\/jats:p>\n                  <jats:p>Forty women with symptomatic uterine AVMs were identified. All presented with vaginal bleeding, the sole symptom in 35 cases (87.5%). Most (31\/40, 77.5%) presented at the emergency department within 24 hours. Thirty-eight women (95%) required one UAE; no hysterectomies were performed. Twelve women (30%) experienced massive bleeding requiring transfusion. Of 35 women who responded to the fertility survey, 22 (62.8%) desired a future pregnancy. Of these, 20 (90.9%) achieved pregnancy, with 17 (85%) delivering at term. The median time to conception was under 6 weeks, and 65% conceived within 12 months. Ten women (50%) had multiple successful pregnancies; one had 5 consecutive pregnancies. Regarding post-UAE pregnancies, 4 women (23.5%) experienced abnormal placentation, but no AVM recurrences were reported.<\/jats:p>\n                  <jats:p>In this cohort, UAE for AVMs is highly effective and fertility-sparing, with most women conceiving and delivering successfully. Obstetric risks remain notable, underscoring the need for larger studies to confirm these findings and assess long-term risks.<\/jats:p>","DOI":"10.1055\/a-2782-1776","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:17:54Z","timestamp":1770769074000},"source":"Crossref","is-referenced-by-count":0,"title":["Fertility and Obstetric and Clinical Outcomes following Embolization Management of Symptomatic Pregnancy-Related Arteriovenous Malformations: Two Decades of Follow-up from a Tertiary Medical Center"],"prefix":"10.1055","author":[{"given":"Perry","family":"Eliassi Revivo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Pekar-Zlotin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Maymon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexei","family":"Cherniavsky","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zalman","family":"Itzhakov","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tal","family":"Fligelman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tal","family":"Rafaeli Yehudai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yair","family":"Shiber","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaniv","family":"Stollero","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2093-0165","authenticated-orcid":false,"given":"Yael","family":"Tal Bliman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zvi","family":"Vaknin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shamir Medical Center affiliated to Gray Faculty of Medicine, Tel Aviv University, Tzrifin, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1097\/01.rvi.0000096761.74047.7d","article-title":"Efficacy of embolization in traumatic uterine vascular malformations","volume":"14","author":"S Ghai","year":"2003","journal-title":"J Vasc Interv Radiol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1097\/00006254-199712000-00004","article-title":"Arteriovenous malformations of the uterus: an uncommon cause of vaginal bleeding","volume":"52","author":"MK Hoffman","year":"1997","journal-title":"Obstet Gynecol Surv"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/0046-8177(95)90043-8","article-title":"Congenital vascular malformation of the uterus in a stillborn: a case report","volume":"26","author":"J Kasznica","year":"1995","journal-title":"Hum 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Gynecol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1002\/j.2205-0140.2012.tb00012.x","article-title":"Pregnancy after uterine arteriovenous malformation-case series and literature review","volume":"15","author":"R Eling","year":"2012","journal-title":"Australas J Ultrasound Med"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1093\/humrep\/det459","article-title":"Uterine artery embolization for severe symptomatic fibroids: effects on fertility and symptoms","volume":"29","author":"A Torre","year":"2014","journal-title":"Hum Reprod"},{"issue":"S 02","key":"ref12","doi-asserted-by":"publisher","first-page":"E92","DOI":"10.1055\/s-0031-1273274","article-title":"Pregnancy-Related Uterine Arteriovenous Malformations: Experience from a Single Medical Center","volume":"32","author":"Z Vaknin","year":"2011","journal-title":"Ultraschall in Med Eur J Ultrasound"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.jmig.2018.05.001","article-title":"Fertility, pregnancy, and clinical outcomes after uterine arteriovenous malformation management","volume":"26","author":"S Delplanque","year":"2019","journal-title":"J Minim Invasive Gynecol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/s0029-7844(02)02347-5","article-title":"Pregnancy after uterine artery embolization","volume":"100","author":"J Goldberg","year":"2002","journal-title":"Obstet Gynecol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1007\/s00270-022-03105-2","article-title":"Fertility Outcomes After Uterine Artery Embolization for Symptomatic Uterine Arteriovenous Malformations: A Single-Center Retrospective Study in 33 Women","volume":"45","author":"H Ghanaati","year":"2022","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.fertnstert.2009.02.069","article-title":"Uterine artery embolization for fibroids is associated with an increased risk of miscarriage","volume":"94","author":"H Homer","year":"2010","journal-title":"Fertil Steril"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3109\/13645706.2012.689768","article-title":"Pregnancy following uterine artery embolization: an update","volume":"22","author":"B McLucas","year":"2013","journal-title":"Minim Invasive Ther Allied Technol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1807","DOI":"10.1111\/jog.12370","article-title":"Disappearance of a uterine arteriovenous malformation following long-term administration of oral norgestrel\/ethinyl estradiol","volume":"40","author":"A Oride","year":"2014","journal-title":"J Obstet Gynaecol Res"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"2485","DOI":"10.1016\/j.ejrad.2015.10.005","article-title":"Vascular uterine abnormalities: comparison of imaging findings and clinical outcomes","volume":"84","author":"C Hugues","year":"2015","journal-title":"Eur J Radiol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"731.e1","DOI":"10.1016\/j.ajog.2015.12.024","article-title":"Ultrasound diagnosis and management of acquired uterine enhanced myometrial vascularity\/arteriovenous malformations","volume":"214","author":"IE Timor-Tritsch","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.gyobfe.2005.05.018","article-title":"Uterine arteriovenous malformation: A rare cause of recurrent metrorrhagia","volume":"33","author":"C Rubod","year":"2005","journal-title":"Gynecol Obstet Fertil"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1097\/01.rvi.0000096761.74047.7d","article-title":"Efficacy of embolization in traumatic uterine vascular malformations","volume":"14","author":"S Ghai","year":"2003","journal-title":"J Vasc Interv Radiol"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1097\/GCO.0b013e328338c179","article-title":"Impact of previous uterine artery embolization on fertility","volume":"22","author":"N Berkane","year":"2010","journal-title":"Curr Opin Obstet Gynecol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1097\/00006250-200402000-00044","article-title":"Uterine artery embolization","volume":"103","author":"ACOG Committee Opinion","year":"2004","journal-title":"Obstet Gynecol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/s1297-9589(03)00188-7","article-title":"Uterine fibroids embolization: results about 454 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Management and Fertility Outcomes","volume":"30","author":"M Jegaden","year":"2023","journal-title":"J Minim Invasive Gynecol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1618","DOI":"10.1016\/j.ajog.2005.05.017","article-title":"Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids (EMMY trial): peri- and postprocedural results from a randomized controlled trial","volume":"193","author":"WJ Hehenkamp","year":"2005","journal-title":"Am J Obstet Gynecol"}],"container-title":["Ultraschall in der Medizin - European Journal of Ultrasound"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2782-1776.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:17:55Z","timestamp":1770769075000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2782-1776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,10]]},"references-count":29,"URL":"https:\/\/doi.org\/10.1055\/a-2782-1776","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0172-4614","1438-8782"],"issn-type":[{"value":"0172-4614","type":"print"},{"value":"1438-8782","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,10]]}}}