{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T14:59:02Z","timestamp":1769007542833,"version":"3.49.0"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Mit Beschluss vom 21. Januar 2025 hat der Sachverst\u00e4ndigen-Ausschuss f\u00fcr Verschreibungspflicht (SVA) in seiner 90. Sitzung mehrheitlich den Antrag abgelehnt, Sildenafil 25 mg und Sildenafil 50 mg zur oralen Anwendung aus der Verschreibungspflicht zu entlassen. In ihrem Statement vom 22. Januar 2025 begr\u00fc\u00dft die Deutsche Gesellschaft f\u00fcr Urologie e.V. diese Entscheidung. \u201eDie ungepr\u00fcfte Einnahme durch den freien Zugang zu dem Wirkstoff birgt relevante Risiken, die nur durch die \u00e4rztliche Verordnung erkannt und vermieden werden k\u00f6nnen. \u00c4rztliche Beratung und Untersuchung k\u00f6nnen Kontraindikationen wie Hypotonie, schwere Herz-Kreislauf-Erkrankung oder bestimmte Augenerkrankungen ausschlie\u00dfen sowie Risiken und Begleiterkrankungen des individuellen Patienten und deren Behandlungsbed\u00fcrftigkeit erkennen. So ist der Hauptgrund f\u00fcr die Einnahme von PDE-5-Hemmern wie Sildenafil eine Erektionsst\u00f6rung, die wissenschaftlich nachgewiesen ein Fr\u00fchwarnsymptom f\u00fcr Herz-Kreislauf-Erkrankungen darstellt und deshalb diagnostisch abgekl\u00e4rt werden muss. (\u2026) Mit dem aktuellen Votum f\u00fcr den Erhalt der Verordnungspflicht setzt das Gremium erneut das richtige Signal f\u00fcr das Patientenwohl.\u201c (Pressemitteilung der DGU vom 22.01.2025) Eine zun\u00e4chst nachvollziehbare Argumentation. Ber\u00fccksichtigt diese Sichtweise aber wirklich alle Facetten im Zusammenhang mit der Verwendung von PDE-5-Inhibitoren und deren Bezug?<\/jats:p>","DOI":"10.1055\/a-2782-4994","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T23:52:17Z","timestamp":1768953137000},"source":"Crossref","is-referenced-by-count":0,"title":["Sachverst\u00e4ndigenausschuss gegen den OTC-Switch von Sildenafil. Gut so! Wirklich? Eine differenzierte Betrachtung."],"prefix":"10.1055","author":[{"given":"Tobias","family":"J\u00e4ger","sequence":"additional","affiliation":[{"name":"Urology, UPK Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"20","DOI":"10.21037\/tau.2016.11.18","article-title":"Aging related erectile dysfunction \u2013 potential mechanism to halt or delay its onset","volume":"6","author":"MG Ferrini","year":"2017","journal-title":"Transl Androl Urol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/sj.ijir.3900622","article-title":"Epidemiology of erectile dysfunction: results of the \u2018Cologne Male Survey\u2019","volume":"12","author":"M Braun","year":"2000","journal-title":"International journal of impotence research"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s11154-020-09541-0","article-title":"Associations between body mass index, waist circumference and erectile dysfunction: a systematic review and meta-analysis","volume":"21","author":"D Pizzol","year":"2020","journal-title":"Rev Endocr Metab Disord"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0276963","article-title":"The association between physical activity and erectile dysfunction: A cross-sectional study in 20,789 Brazilian men","volume":"17","author":"RM Pitta","year":"2022","journal-title":"PLoS One"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/ncpuro0652","article-title":"Smoking, Obesity, and Sedentary Lifestyle Linked to Erectile Dysfunction","volume":"4","author":"C Lovegrove","year":"2007","journal-title":"Nat Clin Pract Urol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1038\/sj.ijo.0803639","article-title":"Body mass index, physical activity and erectile dysfunction: an U-shaped relationship from population-based study","volume":"31","author":"JY Cheng","year":"2007","journal-title":"Int J Obes (Lond)"},{"key":"ref8","first-page":"1624","article-title":"Smoking and erectile dysfunction: Evidence-based analysis","volume":"166","author":"R Shamloul","year":"2013","journal-title":"Journal of Urology"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1111\/jsm.12828","article-title":"A comprehensive review of metabolic syndrome affecting erectile dysfunction","volume":"12","author":"E Kaya","year":"2015","journal-title":"Journal of Sexual Medicine"},{"key":"ref10","first-page":"103","article-title":"The role of testosterone in male sexual function","volume":"23","author":"TH Jones","year":"2022","journal-title":"Reviews in Endocrine and Metabolic Disorders"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1097\/HJH.0000000000002382","article-title":"Update of the position paper on arterial hypertension and erectile dysfunction","volume":"38","author":"M Viigimaa","year":"2020","journal-title":"Journal of Hypertension"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1465","DOI":"10.1007\/s40618-023-02011-9","article-title":"The effects of non-andrological medications on erectile dysfunction: a large single-center retrospective study","author":"R Mazzilli","year":"2023","journal-title":"Endocrinol Invest"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.sxmr.2018.03.008","article-title":"Cardiovascular safety of phosphodiesterase type 5 inhibitors after nearly 2 decades on the market","volume":"6","author":"RA Kloner","year":"2018","journal-title":"Sexual Medicine Reviews"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1093\/jsxmed\/qdac005","article-title":"Effect of phosphodiesterase type 5 inhibitors on major adverse cardiovascular events and overall mortality in a large nationwide cohort of men with erectile dysfunction and cardiovascular risk factors: A retrospective, observational study based on healthcare claims and national death index data","volume":"20","author":"RA Kloner","year":"2013","journal-title":"Journal of Sexual Medicine"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/sj.ijir.3900949","article-title":"Epidemiology of erectile dysfunction","volume":"15","author":"M Kubin","year":"2003","journal-title":"International Journal of Impotence Research"},{"key":"ref17","first-page":"42","article-title":"Rechnen sich rezeptfreie PDE-5-Hemmer f\u00fcr Vor-Ort-Apotheken?","volume":"30","author":"U May","year":"2024","journal-title":"DAZ"},{"key":"ref18","volume-title":"The State of Men\u02bcs Health in Europe Extended Report","author":"A White","year":"2011"},{"key":"ref19","volume-title":"Illicit erectile dysfunction products in the Netherlands. A decade of trends and a 2007\u20132010 product update","author":"BJ Venhuis","year":"2011"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"72","DOI":"10.24945\/MVF.06.24.1866-0533.2676","article-title":"Sind M\u00e4nner unterversorgt? Eine Mixed-Methods-Studie zur Versorgungssituation von M\u00e4nnern in Deutschland","volume":"6","author":"V Amelung","year":"2024","journal-title":"Monitor Versorgungsforschung"},{"key":"ref21","first-page":"372","article-title":"Illegale Online-\u201cApotheken\u201c. Eine rechtliche und strukturelle Analyse illegaler Angebote im Internet","volume":"10","author":"A Sinn","year":"2024","journal-title":"Die Polizei"},{"key":"ref22","first-page":"857","article-title":"Prescription to non-prescription switches in Europe: Overview and impact on self-care and healthcare systems","volume":"41","author":"JG Stevenson","year":"2019","journal-title":"International Journal of Clinical Pharmacy"},{"key":"ref23","first-page":"95","article-title":"Over-the-counter sildenafil in UK pharmacies: Patient perspectives and market development","volume":"45","author":"N Hawkes","year":"2019","journal-title":"BMJ Sexual & Reproductive Health"},{"key":"ref24","first-page":"315","article-title":"The impact of OTC switch of PDE-5 inhibitors in Nordic and Mediterranean countries","volume":"38","author":"H Larsen","year":"2020","journal-title":"Scandinavian Journal of Primary Health Care"},{"key":"ref25","article-title":"Swiss experience with non-prescription availability of sildenafil: Effects on market and healthcare","volume":"151","author":"M Kunz","year":"2021","journal-title":"Swiss Medical Weekly"},{"key":"ref26","first-page":"1243","article-title":"Regulatory evolution and market response to OTC switches for erectile dysfunction drugs in Ireland and Poland","volume":"78","author":"M O'Connell","year":"2022","journal-title":"European Journal of Clinical Pharmacy"}],"container-title":["Aktuelle Urologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2782-4994.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T23:52:20Z","timestamp":1768953140000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2782-4994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,20]]},"references-count":24,"URL":"https:\/\/doi.org\/10.1055\/a-2782-4994","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0001-7868","1438-8820"],"issn-type":[{"value":"0001-7868","type":"print"},{"value":"1438-8820","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,20]]}}}