{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T23:26:57Z","timestamp":1786663617911,"version":"build-2736575974"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Ziel war es, den Anteil pathologischer Ergebnisse im fr\u00fchzeitig\n                        durchgef\u00fchrten 75-g-OGTT bei Frauen mit anamnestischem Sp\u00e4tabort oder\n                        Fr\u00fchgeburt nach Cerclage zu bestimmen. Zudem wurde der Einfluss eines fr\u00fch\n                        diagnostizierten Gestationsdiabetes auf Schwangerschaftsausgang, neonatales\n                        Outcome sowie der Zusammenhang zwischen pr\u00e4konzeptionellem BMI,\n                        OGTT-Ergebnis und Geburtsmodus untersucht.<\/jats:p>\n                  <jats:p>Bei 140 Schwangeren erfolgten zwischen der 16.\u201321. SSW eine prim\u00e4re Cerclage\n                        und ein OGTT. Die Auswertung erfolgte nach Ergebnis (physiologisch vs.\n                        pathologisch). Prim\u00e4rer Endpunkt war der Schwangerschaftsausgang, sekund\u00e4re\n                        Endpunkte umfassten neonatale Parameter, pr\u00e4konzeptionellen BMI und\n                        Geburtsmodus.<\/jats:p>\n                  <jats:p>89 (63%) Frauen zeigten ein pathologisches OGTT-Ergebnis, deutlich h\u00e4ufiger\n                        als in der allgemeinen Schwangerenpopulation. Dieses war nicht signifikant\n                        mit Sp\u00e4tabort oder Fr\u00fchgeburt assoziiert (OR 2,18; p=0,13), zeigte jedoch\n                        eine Risikotendenz. Neonatale Parameter unterschieden sich nicht signifikant\n                        zwischen den Gruppen. Ein pr\u00e4konzeptioneller BMI&gt;35 kg\/m\u00b2 war signifikant\n                        mit einem pathologischen OGTT verkn\u00fcpft (p=0,04). Frauen mit pathologischem\n                        OGTT hatten h\u00e4ufiger eine Sectio als jene mit physiologischem Ergebnis\n                        (55,8% vs.35%).<\/jats:p>\n                  <jats:p>In diesem Hochrisikokollektiv nach Sp\u00e4tabort oder Fr\u00fchgeburt zeigte sich eine\n                        \u00fcberdurchschnittlich hohe Rate pathologischer OGTT-Ergebnisse (63%). Dies\n                        weist auf eine erh\u00f6hte Pr\u00e4disposition f\u00fcr St\u00f6rungen des Glukosestoffwechsels\n                        hin und unterstreicht die Bedeutung eines fr\u00fchzeitigen Glukosescreenings\n                        sowie einer individualisierten Betreuung zur Optimierung des\n                        Schwangerschaftsverlaufs und perinatalen Outcomes.<\/jats:p>","DOI":"10.1055\/a-2784-5295","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:00:08Z","timestamp":1777881608000},"page":"313-322","source":"Crossref","is-referenced-by-count":0,"title":["Bedeutung eines fr\u00fchen 75-g-OGTT zur Erkennung von Glukosest\u00f6rungen\n                    bei Hochrisikopatientinnen nach Sp\u00e4tabort oder Fr\u00fchgeburt"],"prefix":"10.1055","volume":"230","author":[{"given":"Filiz","family":"Markfeld Erol","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Klinik f\u00fcr\n                    Frauenheilkunde, Universit\u00e4tsklinikum Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Riedling","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Quantitative Biologie (QBiC), Eberhard Karls\n                    Universit\u00e4t T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingolf","family":"Juhasz-B\u00f6ss","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Klinik f\u00fcr\n                    Frauenheilkunde, Universit\u00e4tsklinikum Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Kunze","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Klinik f\u00fcr\n                    Frauenheilkunde, Universit\u00e4tsklinikum Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Meschede","sequence":"additional","affiliation":[{"name":"Frauenheilkunde und Geburtshilfe, Klinik f\u00fcr\n                    Frauenheilkunde, Universit\u00e4tsklinikum Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1016\/j.fertnstert.2022.01.004","article-title":"Preterm birth after recurrent pregnancy loss: a systematic review and\n                    meta-analysis","volume":"117","author":"C Q Wu","year":"2022","journal-title":"Fertil Steril"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1111\/1471-0528.17013","article-title":"Risk of preterm birth in relation to history of preterm birth: a\n                    population-based registry study of 213,335 women in 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Neonatologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2784-5295.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T22:32:02Z","timestamp":1786660322000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2784-5295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,4]]},"references-count":32,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2026,8,13]]},"published-print":{"date-parts":[[2026,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2784-5295","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0948-2393","1439-1651"],"issn-type":[{"value":"0948-2393","type":"print"},{"value":"1439-1651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,4]]}}}