{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:10:31Z","timestamp":1778227831845,"version":"3.51.4"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:00Z","timestamp":1767830400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The over-the-scope (OTS) clip system is an established tool for endoscopic management of gastrointestinal bleeding, perforations, fistulas, and, in its modified form as the full-thickness resection device (FTRD), for resection of gastrointestinal lesions. In selected cases, clip removal is required. Conventional techniques often demand costly devices and may be time-consuming. This study evaluated a novel, simple technique for endoscopic removal of OTS and FTRD clips using an endoloop, focusing on feasibility and safety.<\/jats:p>\n                  <jats:p>This prospective single-center study included patients who had undergone OTS or FTRD clip placement and required clip removal between March 2021 and October 2024. The removal procedure involved positioning an endoloop underneath the clip. Follow-up endoscopy within 6 months assessed clip detachment. The primary endpoint was the success rate for clip removal; the secondary endpoint was incidence of adverse events (AEs).<\/jats:p>\n                  <jats:p>A total of 18 patients underwent endoloop-assisted removal of OTS (50%, 9\/18) or FTRD (50%, 9\/18) clips. Endoloop placement was performed at a median of 94 days (range: 27\u2013472) after OTS clip placement and 97 days (range: 0\u2013274) after EFTR. Follow-up endoscopy confirmed clip detachment after a median of 107 days (range: 33\u2013220) for OTS and 114 days (range: 5\u2013203) for FTRD clips. Clip removal was successful in all patients (100%), with no AEs observed.<\/jats:p>\n                  <jats:p>Endoloop-assisted removal of OTS and FTRD clips appears to be effective and safe, representing an addition to current options for endoscopic clip removal.<\/jats:p>","DOI":"10.1055\/a-2784-8740","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:57:32Z","timestamp":1767920252000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Endoloop-assisted endoscopic removal of over-the-scope and full-thickness resection device clips: Prospective study"],"prefix":"10.1055","volume":"14","author":[{"given":"Tobias","family":"Blasberg","sequence":"additional","affiliation":[{"name":"Gastroenterology, Gastrointestinal Oncology and Interventional Endoscopy, Sana Klinikum Offenbach GmbH, Offenbach, Germany"},{"name":"Department of Hepatology and Gastroenterology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Campus Charite Mitte, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Hiebel","sequence":"additional","affiliation":[{"name":"Clinic for Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moritz","family":"Meiborg","sequence":"additional","affiliation":[{"name":"Gastroenterology, Gastrointestinal Oncology and Interventional Endoscopy, Sana Klinikum Offenbach GmbH, Offenbach, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Richl","sequence":"additional","affiliation":[{"name":"Gastroenterology, Gastrointestinal Oncology and Interventional Endoscopy, Sana Klinikum Offenbach GmbH, Offenbach, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian Alexander","family":"Michael","sequence":"additional","affiliation":[{"name":"Department of Medicine I Gastroenterology Hepatology Pneumology Allergology Endocrinology Diabetology, Medical Clinic 1, University Hospital Frankfurt, Frankfurt, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Seif Amir Hosseini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Interventional Radiology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Amanzada","sequence":"additional","affiliation":[{"name":"Clinic for Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volker","family":"Ellenrieder","sequence":"additional","affiliation":[{"name":"Clinic for Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juergen","family":"Hochberger","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Gastroenterology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Campus Charite Mitte, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wedi","family":"Edris","sequence":"additional","affiliation":[{"name":"Gastroenterology, Gastrointestinal Oncology and Interventional Endoscopy, Sana Klinikum Offenbach GmbH, Offenbach, Germany"},{"name":"Clinic for Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.gie.2007.01.034","article-title":"A new endoscopic over-the-scope clip system for treatment of lesions and bleeding in the GI tract: first clinical experiences","volume":"66","author":"A Kirschniak","year":"2007","journal-title":"Gastrointest Endosc"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1844","DOI":"10.3748\/wjg.v22.i5.1844","article-title":"One hundred and one over-the-scope-clip applications for severe gastrointestinal bleeding, leaks and fistulas","volume":"22","author":"E Wedi","year":"2016","journal-title":"World J Gastroenterol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/jgh.14402","article-title":"Over-the-scope clip system: A review of 1517 cases over 9 years","volume":"34","author":"H Kobara","year":"2019","journal-title":"J Gastroenterol Hepatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1055\/a-2304-3219","article-title":"Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 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Jung","year":"2020","journal-title":"Endoscopy"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1080\/13645706.2019.1590417","article-title":"Long-term assessment of over-the-scope clip (OTSC) behavior after gastric application","volume":"29","author":"J Hu","year":"2020","journal-title":"Minim Invasive Ther Allied Technol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1136\/gutjnl-2016-313677","article-title":"Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in various indications","volume":"67","author":"A Schmidt","year":"2018","journal-title":"Gut"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1055\/a-2328-4753","article-title":"Technical failure during colorectal endoscopic full-thickness resection: the \"through thick and thin\" study","volume":"56","author":"G Gibiino","year":"2024","journal-title":"Endoscopy"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1111\/den.14631","article-title":"Device-assisted endoscopic full-thickness resection in colorectum: Systematic review and meta-analysis","volume":"36","author":"Z Nabi","year":"2024","journal-title":"Dig Endosc"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.gie.2010.07.033","article-title":"Endoscopic closure of GI fistulae by using an over-the-scope clip (with videos)","volume":"72","author":"D von Renteln","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1055\/s-0029-1245871","article-title":"Removal of over the scope clips (OTSC) with an Nd:YAG Laser","volume":"49","author":"M Fahndrich","year":"2011","journal-title":"Z Gastroenterol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1111\/den.12925","article-title":"Argon plasma coagulation for successful fragmentation and removal of an over-the-scope clip","volume":"29","author":"S Kapadia","year":"2017","journal-title":"Dig Endosc"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1016\/j.gie.2013.11.010","article-title":"An over-the-scope clipping device inadvertently sealing the pylorus: first description of a removal method","volume":"79","author":"A Sedarat","year":"2014","journal-title":"Gastrointest Endosc"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1016\/j.gie.2015.05.029","article-title":"Two endoscopic resection methods for the removal of an over-the-scope clip","volume":"82","author":"S Mumtaz","year":"2015","journal-title":"Gastrointest 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endoscopic full-thickness resection (EFTR) with the over-the-scope device (FTRD): A multicenter Italian experience","volume":"51","author":"G Andrisani","year":"2019","journal-title":"Dig Liver Dis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s00464-019-06839-2","article-title":"Endoscopic full-thickness resection of gastric subepithelial tumors with the gFTRD-system: a prospective pilot study (RESET trial)","volume":"34","author":"B Meier","year":"2020","journal-title":"Surg Endosc"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s00464-017-5676-9","article-title":"Safe and successful resection of difficult GI lesions using a novel single-step full-thickness resection device (FTRD)","volume":"32","author":"PV Valli","year":"2018","journal-title":"Surg Endosc"}],"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2784-8740.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T07:16:42Z","timestamp":1778224602000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2784-8740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,8]]},"references-count":31,"journal-issue":{"issue":"CP","published-online":{"date-parts":[[2026,1,13]]},"published-print":{"date-parts":[[2026]]}},"alternative-id":["a27848740"],"URL":"https:\/\/doi.org\/10.1055\/a-2784-8740","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1,8]]},"published":{"date-parts":[[2026,1,8]]}}}