{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:10:35Z","timestamp":1778227835790,"version":"3.51.4"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Endoscopic resection of large, broad-based pedunculated and semi-pedunculated polyps can be technically difficult. Conventional snare resection risks immediate bleeding and piecemeal excision. We evaluated the safety and efficacy of a scissor-type endoscopic submucosal dissection (ST-ESD) knife for these lesions.<\/jats:p>\n                  <jats:p>A single-center retrospective study was conducted of all patients who underwent ST-ESD resection of pedunculated or semi-pedunculated polyps with head size \u2267 20 mm and stalk width \u2267 10 mm. Primary outcomes were en bloc resection, intraprocedural and delayed bleeding, and perforation. Secondary outcomes were R0 resection and recurrence at first follow-up.<\/jats:p>\n                  <jats:p>Fifty-eight resections were identified (75.6% male; median age 60 years). Median head size was 30 mm (range 20\u201370) with median stalk width 15 mm (range 10\u201350). Of them, 74.1% were in the sigmoid colon. Successful resection was achieved in 52 of 58 (89.7%); 44 (75.9%) by ST-ESD alone and eight (13.8%) snare-assisted. Six (10.3%) were abandoned; five due to visible muscle retraction and one dense stalk fibrosis. All successful resections were en bloc with R0 in 52 of 52 (100%). Minor intraprocedural bleeding occurred in nine of 58 (15.5%) and was controlled endoscopically. Forty-seven of 52 defects (90.4%) were closed prophylactically with endoscopic clips. There were no incidences of delayed bleeding or perforation. Histopathology was benign in 51 of 52 (98.1%). One adenocarcinoma was treated surgically for high-risk features. Endoscopic follow-up was available in 41 of 52 (78.8%) with no recurrence seen. Zero of six abandoned cases referred for surgery contained evidence of malignancy in the surgical specimen.<\/jats:p>\n                  <jats:p>ST-ESD is safe and effective for resection of large, broad-based pedunculated and semi-pedunculated colorectal polyps.<\/jats:p>","DOI":"10.1055\/a-2788-3249","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T23:51:19Z","timestamp":1768521079000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Resection of large, broad-based pedunculated and semi-pedunculated colorectal polyps using a scissor-type endoscopic submucosal dissection knife"],"prefix":"10.1055","volume":"14","author":[{"given":"Robert","family":"Eckersley","sequence":"additional","affiliation":[{"name":"Wolfson Unit for Endoscopy, St Mark's Hospital and Academic Institute, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Wolfson Unit for Endoscopy, St Mark's Hospital and Academic Institute, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Saunders","sequence":"additional","affiliation":[{"name":"Wolfson Unit for Endoscopy, St Mark's Hospital and Academic Institute, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Humphries","sequence":"additional","affiliation":[{"name":"Wolfson Unit for Endoscopy, St Mark's Hospital and Academic Institute, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2364","DOI":"10.3748\/wjg.14.2364","article-title":"Efficacy, risk factors and complications of endoscopic polypectomy: Ten year experience at a single center","volume":"14","author":"P Consolo","year":"2008","journal-title":"World J Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1007\/s00464-003-9214-6","article-title":"Prophylactic submucosal saline-adrenaline injection in colonoscopic polypectomy: Prospective randomized study","volume":"18","author":"S Dobrowolski","year":"2004","journal-title":"Surg Endosc Other Intervent Techniq"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.3748\/wjg.v13.i21.2973","article-title":"Comparison of postpolypectomy bleeding between epinephrine and saline submucosal injection for large 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Albouys","year":"2024","journal-title":"Gastrointest Endosc"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"E757","DOI":"10.1055\/a-2316-7755","article-title":"Outcomes in colorectal endoscopic submucosal dissection for large protruded lesions: A retrospective multicenter study","volume":"12","author":"H Chiba","year":"2024","journal-title":"Endosc Int Open"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"E1437","DOI":"10.1055\/a-2427-1948","article-title":"Endoscopic submucosal dissection of colorectal pedunculated polyps","volume":"12","author":"JK Jakobs","year":"2024","journal-title":"Endosc Int Open"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/a-1194-4413","article-title":"Endoscopic submucosal dissection of large pedunculated polyps with wide stalks: A retrospective multicenter study","volume":"53","author":"H 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