{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T02:44:57Z","timestamp":1792118697960,"version":"4.4.0"},"reference-count":88,"publisher":"Georg Thieme Verlag KG","issue":"02\/03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Drug Res (Stuttg)"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>Liposomes are artificially constructed, phospholipid-based vesicular systems\n                        that have emerged as vital components in pharmaceutical nanotechnology and\n                        advanced drug delivery. Their flexible bilayered structure enables the\n                        encapsulation of a broad spectrum of therapeutic agents, enhancing drug\n                        stability and bioavailability. Since their discovery, liposomes have been\n                        widely explored as efficient drug carriers and diagnostic tools due to their\n                        superior capacity to deliver active pharmaceutical ingredients precisely to\n                        target sites. Their inherent advantages including high biocompatibility, the\n                        enhanced permeability and retention effect for passive tumor targeting,\n                        customizable surface modification for improved targeting efficiency, and\n                        enhanced physicochemical stability collectively position them as promising\n                        nanocarriers for cancer therapy and other biomedical applications.\n                        Liposomes, as synthetic nanoscale vesicles, offer significant promise for\n                        immunotherapeutic interventions due to their capability to codeliver\n                        antigens and adjuvants while modulating immune cell behavior. Specialized\n                        formulations such as immunoliposomes, virosomes, and other immunostimulatory\n                        complexes engineered with specific ligands or immune active moieties exhibit\n                        unique structural and functional profiles that enhance anticancer immune\n                        responses. Furthermore, liposomes facilitate targeted cargo delivery to\n                        immune cells, influencing their phenotype and functional activity. This\n                        review presents an integrated overview of liposomal composition, structural\n                        attributes, mechanisms of drug delivery, therapeutic applications, and\n                        clinical progress. The use of liposomes in delivering small molecules,\n                        macromolecules, and nucleic acids has demonstrated significant advancements,\n                        underscoring their expanding role in modern therapeutics. Overall, this\n                        article provides a comprehensive and up-to-date examination of liposome\n                        technology and its clinical translational potential.<\/jats:p>","DOI":"10.1055\/a-2795-7008","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:31:28Z","timestamp":1772065888000},"page":"65-81","source":"Crossref","is-referenced-by-count":13,"title":["Translational Insights into Liposomal Drug Delivery: Recent Advances,\n                    Therapeutic Applications, and Clinical Trials"],"prefix":"10.1055","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9794-1390","authenticated-orcid":false,"given":"Abdul","family":"Shadab","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Integral University, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Faiz","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Basic Science 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Binaymotlagh","year":"2024","journal-title":"Gels"},{"issue":"02","key":"ref47","first-page":"117","article-title":"Vesicular nanocarrier based treatment of skin fungal infections: potential and\n                    emerging trends in nanoscale pharmacotherapy","volume":"14","author":"S Verma","year":"2019","journal-title":"Asian J Pharm Sci"},{"issue":"10","key":"ref48","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.3390\/pharmaceutics14102165","article-title":"Liposomal drug delivery systems for cancer therapy: the rotterdam\n                    experience","volume":"14","author":"M Amin","year":"2022","journal-title":"Pharmaceutics"},{"issue":"02","key":"ref49","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3390\/pharmaceutics9020012","article-title":"Liposomal formulations in clinical use: an updated review","volume":"9","author":"U Bulbake","year":"2017","journal-title":"Pharmaceutics"},{"issue":"01","key":"ref50","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3390\/pharmaceutics17010036","article-title":"Liposomal formulations: a recent update","volume":"17","author":"S S Agrawal","year":"2025","journal-title":"Pharmaceutics"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"326497","DOI":"10.1155\/2011\/326497","article-title":"Liposomes for use in gene delivery","volume":"2011","author":"D A Balazs","year":"2011","journal-title":"J Drug Deliv"},{"issue":"09","key":"ref52","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.3390\/pr12091970","article-title":"Innovative and patented liposome-based drug carriers","volume":"12","author":"S Ili\u0107-Stojanovi\u0107","year":"2024","journal-title":"Processes"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"100209","DOI":"10.1016\/j.nxnano.2025.100209","article-title":"Liposomes for drug delivery: classification, therapeutic 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Wang","year":"2015","journal-title":"Int J Nanomedicine"},{"issue":"20","key":"ref57","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.3390\/molecules29204889","article-title":"Recent progress in terrestrial biota derived antibacterial agents for medical\n                    applications","volume":"29","author":"T G Vladkova","year":"2024","journal-title":"Molecules"},{"issue":"04","key":"ref58","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s13139-019-00603-z","article-title":"Theranostics based on liposome: looking back and forward","volume":"53","author":"W Lee","year":"2019","journal-title":"Nucl Med Mol Imaging"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.addr.2019.03.003","article-title":"Lyophilized liposome-based parenteral drug development: reviewing complex\n                    product design strategies and current regulatory environments","volume":"151\u2013152","author":"Y Wang","year":"2019","journal-title":"Adv Drug Deliv Rev"},{"issue":"10","key":"ref60","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.3390\/pharmaceutics15102431","article-title":"Pediatric drug development: reviewing challenges and opportunities by tracking\n                    innovative therapies","volume":"15","author":"C Domingues","year":"2023","journal-title":"Pharmaceutics"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"100165","DOI":"10.1016\/j.medidd.2023.100165","article-title":"Lipid polymer hybrid nanoparticles as potent vehicles for drug delivery in\n                    cancer therapeutics","volume":"20","author":"S Parveen","year":"2023","journal-title":"Med Drug Discov"},{"issue":"04","key":"ref62","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s40265-016-0538-7","article-title":"Liposomal amphotericin B (AmBisome(\u00ae)): a review of the pharmacokinetics,\n                    pharmacodynamics, clinical experience and future 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Polym"},{"issue":"04","key":"ref69","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3390\/molecules23040907","article-title":"Liposomal drug delivery systems and anticancer drugs","volume":"23","author":"TO B Olusanya","year":"2018","journal-title":"Molecules"},{"issue":"10","key":"ref70","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.3390\/vaccines10101575","article-title":"The interplay of oxidative stress and ROS scavenging: antioxidants as a\n                    therapeutic potential in sepsis","volume":"10","author":"S Kumar","year":"2022","journal-title":"Vaccines (Basel)"},{"issue":"02","key":"ref71","doi-asserted-by":"crossref","first-page":"288","DOI":"10.3390\/molecules23020288","article-title":"Liposomes: clinical applications and potential for image-guided drug\n                    delivery","volume":"23","author":"N Lamichhane","year":"2018","journal-title":"Molecules"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"12485","DOI":"10.2147\/IJN.S538382","article-title":"Liposome-based nanoparticle delivery systems for lung diseases: opportunities\n                    and challenges","volume":"20","author":"X Zhang","year":"2025","journal-title":"Int J Nanomedicine"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3390\/antiox9020181","article-title":"Collagen hydrolysates for skin protection: oral administration and topical\n                    formulation","volume":"9","author":"G Aguirre-Cruz","year":"2020","journal-title":"Antioxidants"},{"issue":"20","key":"ref74","doi-asserted-by":"crossref","first-page":"12487","DOI":"10.3390\/ijms232012487","article-title":"The role of cryoprotective agents in liposome stabilization and\n                    preservation","volume":"23","author":"G F Boafo","year":"2022","journal-title":"Int J Mol 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