{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T23:21:09Z","timestamp":1779405669998,"version":"3.53.1"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"06","funder":[{"DOI":"10.13039\/501100007687","name":"Swedish Society of Medicine","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007687","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Swedish Cancer Society"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Post-endoscopy esophageal cancer (PEEC) (i.e. esophageal cancer diagnosed shortly after an endoscopy in which no cancer was found) constitutes about 5%\u201310% of all esophageal cancers. Long-term survival in PEEC has not been reported previously.<\/jats:p>\n                  <jats:p>This population-based cohort study included patients with a newly diagnosed esophageal cancer in Denmark, Finland, and Sweden between 2004 and 2022. Patients with PEEC (i.e. history of upper endoscopy 6\u201336 months before esophageal cancer diagnosis) were compared with patients with all other esophageal cancers (i.e. those without upper endoscopy 6\u201336 months before diagnosis). Outcomes were 5-year disease-specific mortality and 5-year all-cause mortality. Multivariable Cox regression was used to calculate hazard ratios (HRs) with 95%CIs, adjusted for country, age, sex, calendar year, comorbidity, and tumor histology.<\/jats:p>\n                  <jats:p>Among 27 309 patients with esophageal cancer, 1588 (5.8%) were classified as having PEEC. The cumulative 5-year mortality among patients with PEEC was 74.6% (n = 1185), and 79.6% of these were disease-specific deaths (n = 943). PEEC was associated with decreased risks of both 5-year disease-specific mortality (HR 0.72, 95%CI 0.68\u20130.77) and 5-year all-cause mortality (HR 0.74, 95%CI 0.71\u20130.80). Stratified analysis found that the decreased 5-year disease-specific mortality in PEEC was limited to patients with adenocarcinoma (HR 0.57, 95%CI 0.52\u20130.62), whereas no such decrease was found among patients with squamous cell carcinoma (HR 1.04, 95%CI 0.95\u20131.15).<\/jats:p>\n                  <jats:p>5-year survival in patients with PEEC seemed to be better than in those with other esophageal cancer, but the survival was still poor.<\/jats:p>","DOI":"10.1055\/a-2807-8630","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T23:51:49Z","timestamp":1770421909000},"page":"588-594","source":"Crossref","is-referenced-by-count":0,"title":["Survival in post-endoscopy esophageal cancer: a Nordic population-based cohort study"],"prefix":"10.1055","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1000-5422","authenticated-orcid":false,"given":"Dag","family":"Holmberg","sequence":"additional","affiliation":[{"name":"Karolinska Institutet, 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Norway","place":["Trondheim"],"department":["Department of Public Health and Nursing"]},{"name":"Levanger Hospital, Nord-Tr\u00f8ndelag Hospital Trust, Norway","place":["Levanger"],"department":["Medical Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"My","family":"Von Euler-Chelpin","sequence":"additional","affiliation":[{"name":"University of Copenhagen, Denmark","place":["Copenhagen"],"department":["Department of Public Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joonas H.","family":"Kauppila","sequence":"additional","affiliation":[{"name":"Karolinska Institutet, Sweden","place":["Stockholm"],"department":["Department of Molecular Medicine and Surgery"]},{"name":"Oulu University Hospital and University of Oulu, Finland","place":["Oulu"],"department":["Department of Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giola","family":"Santoni","sequence":"additional","affiliation":[{"name":"Karolinska 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