{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:04:46Z","timestamp":1784588686068,"version":"3.55.0"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Musculoskelet Radiol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Nodular soft tissue abnormalities are common in the foot and ankle and often demonstrate overlapping magnetic resonance imaging features, typically showing high signal intensity on T2-weighted sequences. In contrast, T2-weighted hypointense soft tissue nodules are less common and encompass a range of neoplastic and pseudotumoral entities. Among these, Morton's neuroma is likely the most prevalent abnormality; however, other less common but clinically relevant lesions may appear with similar imaging features.<\/jats:p>\n                  <jats:p>This article focuses on three such conditions: rheumatoid nodules, tophaceous gout, and tenosynovial giant cell tumor. Although the imaging findings of these lesions themselves are often nonspecific, the associated features can provide important diagnostic clues. Rheumatoid nodules typically occur around the metatarsophalangeal joints, in areas subject to repeated mechanical stress, and usually present as multiple lesions with accompanying intermetatarsal bursitis. In contrast, tophaceous gout is rarely associated with interdigital bursitis, but more commonly it shows diffuse fatty muscle infiltration. Tenosynovial giant cell tumors are typically limited to a single joint space or tendon sheath and usually not associated with bursitis, pseudobursae, or fatty infiltration of the muscles.<\/jats:p>","DOI":"10.1055\/a-2808-2134","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:35:56Z","timestamp":1777588556000},"page":"505-514","source":"Crossref","is-referenced-by-count":0,"title":["Magnetic Resonance Imaging of T2-weighted Hypointense Nodular Lesions of the Foot and Ankle: A Pictorial Review of Rheumatoid Nodules, Tophaceous Gout, and Tenosynovial Giant Cell Tumor"],"prefix":"10.1055","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4625-989X","authenticated-orcid":false,"given":"Fabian Nicolas","family":"Jud","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cantonal Hospital Baden, Baden, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja","family":"Mamisch-Saupe","sequence":"additional","affiliation":[{"name":"Department of Musculoskeletal Radiology, Clinic Hirslanden, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Fritz","sequence":"additional","affiliation":[{"name":"Department of Radiology, Balgrist University Hospital and University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Zanetti","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cantonal Hospital Baden, Baden, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"101872","DOI":"10.1016\/j.jcot.2022.101872","article-title":"MRI imaging of soft tissues tumours and tumour like lesions-SLAM approach","volume":"28","author":"R Vadapalli","year":"2022","journal-title":"J Clin Orthop Trauma"},{"issue":"09","key":"ref2","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.3113\/FAI.2007.1007","article-title":"An anatomical study of Morton's interdigital neuroma: the relationship between the occurring site and the deep transverse metatarsal ligament (DTML)","volume":"28","author":"J Y Kim","year":"2007","journal-title":"Foot Ankle Int"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0140-6736(16)30173-8","article-title":"Rheumatoid arthritis","volume":"388","author":"J S Smolen","year":"2016","journal-title":"Lancet"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1055\/s-0045-1802952","article-title":"Imaging updates in rheumatoid arthritis","volume":"29","author":"W R Walter","year":"2025","journal-title":"Semin Musculoskelet Radiol"},{"issue":"09","key":"ref5","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1002\/art.27584","article-title":"2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"62","author":"D Aletaha","year":"2010","journal-title":"Arthritis Rheum"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1186\/s12891-019-2773-z","article-title":"Prevalence of feet and ankle arthritis and their impact on clinical indices in patients with rheumatoid arthritis: a cross-sectional study","volume":"20","author":"S W Lee","year":"2019","journal-title":"BMC Musculoskelet Disord"},{"issue":"02","key":"ref7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jaad.2004.07.023","article-title":"Rheumatoid arthritis: a review of the cutaneous manifestations","volume":"53","author":"A Sayah","year":"2005","journal-title":"J Am Acad Dermatol"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.autrev.2011.09.001","article-title":"Extra-articular manifestations of rheumatoid arthritis: an update","volume":"11","author":"M Prete","year":"2011","journal-title":"Autoimmun Rev"},{"issue":"02","key":"ref9","first-page":"279","article-title":"Rheumatoid nodules. 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