{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:59:22Z","timestamp":1790272762459,"version":"4.1.0"},"reference-count":105,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Musculoskelet Radiol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Spinal interventional radiology has witnessed substantial progress in recent years. Notable recent advances include expanded adoption of vertebral augmentation techniques, targeted thermal ablation combined with cement augmentation to treat spinal metastases, electrochemotherapy for radioresistant epidural metastases, improved precision in facet joint, medial branch, and sacroiliac interventions, basivertebral nerve ablation for vertebrogenic back pain and emerging applications of restorative neurostimulation, and minimally invasive neuromodulation for chronic mechanical back pain. This review provides an overview of recent advances in the field, emerging treatments, and predictions for future breakthroughs.<\/jats:p>","DOI":"10.1055\/a-2820-0900","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T22:47:11Z","timestamp":1774910831000},"page":"361-378","source":"Crossref","is-referenced-by-count":1,"title":["Recent Advances and Immediate Future of Spinal Intervention"],"prefix":"10.1055","volume":"30","author":[{"given":"Patrick","family":"Baker","sequence":"additional","affiliation":[{"name":"Buckinghamshire Healthcare NHS Trust, Stoke Mandeville Hospital, Aylesbury, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devpriyo","family":"Pal","sequence":"additional","affiliation":[{"name":"Buckinghamshire Healthcare NHS Trust, Stoke Mandeville Hospital, Aylesbury, United 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Buchbinder","year":"2009","journal-title":"N Engl J Med"},{"issue":"06","key":"ref61","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1056\/NEJMoa0900563","article-title":"A randomized trial of vertebroplasty for osteoporotic spinal fractures","volume":"361","author":"D F Kallmes","year":"2009","journal-title":"N Engl J Med"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"k1551","DOI":"10.1136\/bmj.k1551","article-title":"Vertebroplasty versus sham procedure for painful acute osteoporotic vertebral compression fractures (VERTOS IV): randomised sham controlled clinical trial","volume":"361","author":"C E Firanescu","year":"2018","journal-title":"BMJ"},{"issue":"16","key":"ref63","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1001\/jama.297.16.1772-b","article-title":"Effect of 10 days of bed rest on skeletal muscle in healthy older adults","volume":"297","author":"P 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Puijk","year":"2021","journal-title":"Radiology"},{"issue":"09","key":"ref84","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s00270-016-1402-6","article-title":"Image-guided spinal ablation: a review","volume":"39","author":"G Tsoumakidou","year":"2016","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"02","key":"ref85","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1200\/JCO.2004.03.097","article-title":"Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study","volume":"22","author":"M P Goetz","year":"2004","journal-title":"J Clin Oncol"},{"issue":"22","key":"ref87","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1097\/BRS.0b013e3181b8b6f5","article-title":"Radiotherapy and radiosurgery for metastatic spine disease: what are the options, indications, and outcomes?","volume":"34","author":"P C 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