{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T22:53:53Z","timestamp":1782168833053,"version":"3.54.5"},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"13","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Bundesministerium f\u00fcr Bildung und Forschung, Netzwerks Universit\u00e4tsmedizin (NUM), Teilprojekt NUM-PREPARED","award":["01KX2121"],"award-info":[{"award-number":["01KX2121"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Dengue-Fieber ist eine m\u00fccken\u00fcbertragene virale Infektionskrankheit mit global gesch\u00e4tzten 100\u2013400 Millionen Infektionen j\u00e4hrlich. Die aktuell h\u00f6chsten Fallzahlen schlagen sich auch in den spezialisierten Zentren in Deutschland nieder. Ein Pilotprojekt zur Surveillance hoch-infekti\u00f6ser importierter Erkrankungen der tropenmedizinischen Zentren in Berlin, Heidelberg und Augsburg nutzte Dengue-Fieber zur Pilotierung gemeinsamer Datenerfassung, -\u00fcbermittlung, und -analyse.<\/jats:p>\n                  <jats:p>Patienten und Patientinnen mit Dengue-Fieber wurden in die Erhebung eingeschlossen. Demografische, anamnestische und klinisch-laborchemische Daten wurden erfasst und anschlie\u00dfend in eine online, f\u00fcr alle beteiligten Zentren zug\u00e4ngliche, Datenbank (RedCap) \u00fcbertragen.<\/jats:p>\n                  <jats:p>In der Pilotphase (August bis Dezember 2023) wurden 42 Patienten und Patientinnen eingeschlossen (Altersmedian: 35,5 Jahre; Reisedauer: Median 20 Tage). Die Infektionsl\u00e4nder lagen in S\u00fcd(ost)asien (64,3%), Mittelamerika (30,9%) und Afrika (4,8%). Die meist klassischen Symptome (Fieber, Kopfschmerzen, Gelenk- und Muskelschmerzen, Exanthem) begannen bei nahezu zwei Drittel bereits w\u00e4hrend der Reise. Die Diagnose beruhte bei 71,4% auf dem Nachweis des NS1-Antigens und bei 28,6% auf der Serologie. Das pilotierte System erwies sich als praktikabel zur Erfassung von infekti\u00f6sen Bedrohungen im Sinne einer Pandemic Preparedness.<\/jats:p>\n                  <jats:p>Die gemeinsame Erfassung einer Infektionskrankheit wurde erfolgreich pilotiert. Dengue-Fieber zeigte sich in klassischer Auspr\u00e4gung. Wachsende Fallzahlen und das Risiko einer autochthonen \u00dcbertragung r\u00fccken Dengue-Fieber auch in Deutschland zunehmend in den differentialdiagnostischen Fokus.<\/jats:p>","DOI":"10.1055\/a-2828-3673","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T22:41:32Z","timestamp":1776811292000},"page":"e42-e46","source":"Crossref","is-referenced-by-count":0,"title":["Charakterisierung importierter Dengue-Fieber-F\u00e4lle in Deutschland"],"prefix":"10.1055","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7373-0897","authenticated-orcid":false,"given":"Mia","family":"Wintel","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin; Charit\u00e9 Center for Global Health, Institut f\u00fcr Internationale Gesundheit, Deutschland","place":["Berlin"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Bernhard","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin; Charit\u00e9 Center for Global Health, Institut f\u00fcr Internationale Gesundheit, Deutschland","place":["Berlin"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia S.","family":"Beck","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Heidelberg, Zentrum f\u00fcr Infektiologie, Abteilung Infektions- und Tropenmedizin, Deutschland","place":["Heidelberg"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Augsburg, III. 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