{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T05:10:32Z","timestamp":1777785032825,"version":"3.51.4"},"reference-count":39,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Photon-counting computed tomography (PCCT) offers new possibilities for optimizing image quality while reducing radiation dose. However, the influence of acquisition parameters such as tube voltage and spectral shaping with tin filtration on chest imaging remains insufficiently understood.<\/jats:p>\n                  <jats:p>Adult male and female anthropomorphic phantoms were scanned using a dual-source PCCT system across a broad range of image quality levels (IQL 1\u2013100). Radiation dose and signal-to-noise ratio (SNR) were evaluated for protocols using 120 kVp and 140 kVp without tin filtration, and 100 kVp with tin filtration.<\/jats:p>\n                  <jats:p>The male phantom required a significantly higher tube current and radiation dose than the female, reflecting sex-based attenuation differences. Increasing the tube voltage to 140 kVp raised the radiation dose with minimal SNR improvement. Tin filtration substantially reduced the dose despite a higher mAs, with the radiation dose and tube current plateauing near IQL 80. In the low-dose range (IQL 1\u201320), tin filtration enabled dose reduction without saturation. Slight SNR trade-offs between bone and mediastinum highlight the need for tissue-specific considerations when optimizing PCCT chest protocols.<\/jats:p>\n                  <jats:p>Sex- and tissue-specific differences with tin filtration and varying tube voltages underscore baseline differences in radiation dose and image quality behavior between representative adult body geometries. These baseline relationships provide a technical foundation for future patient-specific protocol optimization.<\/jats:p>","DOI":"10.1055\/a-2829-0195","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T23:39:02Z","timestamp":1774395542000},"source":"Crossref","is-referenced-by-count":1,"title":["Influence of Tube Voltage, Tin Filtration, and Sex on Radiation Dose and Image Quality in Adult Chest Photon-Counting CT: A Phantom-Based Signal-to-Noise-Based Analysis"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7850-3589","authenticated-orcid":false,"given":"Laura Valentina","family":"Kl\u00fcner","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2997-0740","authenticated-orcid":false,"given":"Sebastian","family":"Zensen","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"aus der Wiesche","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Duisburg-Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Ebenau","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, West German Cancer Center, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9585-9787","authenticated-orcid":false,"given":"Denise","family":"Bos","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raya","family":"Ocker-Serger","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berk","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0719-2207","authenticated-orcid":false,"given":"Mathias","family":"Holtkamp","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Salh\u00f6fer","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nika","family":"Guberina","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, West German Cancer Center, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Buescher","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Ruhrlandklinik, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Welsner","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Ruhrlandklinik, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedikt","family":"Schaarschmidt","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel","family":"Drews","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lale","family":"Umutlu","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology and Neuroradiology, University 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