{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:04:26Z","timestamp":1780095866223,"version":"3.54.0"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Trigeminal trophic syndrome (TTS) is a rare neurocutaneous disorder defined by trigeminal anesthesia, facial paresthesia, and crescentic ulceration of the nasal ala. We describe an 86-year-old woman with long-standing trigeminal neuralgia who developed a suspicious ulcerated lesion on the left nasal ala. Although the initial biopsy showed atypical squamous cells suggestive of squamous cell carcinoma, the combined histopathologic, radiologic, and clinical findings supported a diagnosis of TTS. This case underscores the need to distinguish TTS from malignancy, particularly in elderly patients with neurologic comorbidities. Early recognition may prevent unnecessary invasive procedures and improve outcomes.<\/jats:p>","DOI":"10.1055\/a-2833-4794","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:01:11Z","timestamp":1773705671000},"page":"253-256","source":"Crossref","is-referenced-by-count":0,"title":["Trigeminal Trophic Syndrome: A Case Report and Literature Review"],"prefix":"10.1055","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5520-0250","authenticated-orcid":false,"given":"Han-Sang","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Korea University Ansan Hospital, Ansan, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3382-560X","authenticated-orcid":false,"given":"Il-Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Korea University Ansan Hospital, Ansan, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9997-2736","authenticated-orcid":false,"given":"Hi-Jin","family":"You","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Korea University Ansan Hospital, Ansan, Republic of Korea"},{"name":"Institute of Advanced Regeneration and Reconstruction, College of Medicine, Korea University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4225-002X","authenticated-orcid":false,"given":"Deok-Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Korea University Ansan Hospital, Ansan, Republic of Korea"},{"name":"Institute of Advanced Regeneration and Reconstruction, College of Medicine, Korea University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6511-5453","authenticated-orcid":false,"given":"Tae-Yul","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Korea University Ansan Hospital, Ansan, Republic of Korea"},{"name":"Institute of Advanced Regeneration and Reconstruction, College of Medicine, Korea University, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,5,29]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/ijd.14098","article-title":"Trigeminal trophic syndrome: An updated review","volume":"58","author":"A U Khan","year":"2019","journal-title":"Int J Dermatol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/BF01667573","article-title":"Klinische Beitr\u00e4ge zur Diagnostik acuter Herderkrankungen des verl\u00e4ngerten Markes und der Br\u00fccke","volume":"19","author":"A Wallenberg","year":"1901","journal-title":"Dtsch Z Nervenheilk"},{"issue":"12","key":"ref3","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1288\/00005537-198812000-00009","article-title":"Trigeminal trophic syndrome","volume":"98","author":"R Arasi","year":"1988","journal-title":"Laryngoscope"},{"issue":"06","key":"ref4","first-page":"949","article-title":"The trigeminal trophic syndrome: an unusual cause of nasal ulceration","volume":"50","author":"S U Monrad","year":"2004","journal-title":"J Am Acad Dermatol"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1136\/jnnp.39.2.105","article-title":"Trigeminal neuropathy with nasal ulceration: report of two cases and one necropsy","volume":"39","author":"J D Spillane","year":"1976","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/1346-8138.12490","article-title":"Trigeminal trophic syndrome: Report of a case and review of the published work","volume":"41","author":"T Sawada","year":"2014","journal-title":"J Dermatol"},{"issue":"05","key":"ref7","first-page":"807","article-title":"Trigeminal trophic syndrome\u2013report of four cases and review of the literature","volume":"30","author":"P Sadeghi","year":"2004","journal-title":"Dermatol Surg"},{"issue":"02","key":"ref8","first-page":"121","article-title":"Trigeminal trophic syndrome leading to orbital cellulitis","volume":"2","author":"L B Thompson","year":"2018","journal-title":"Clin Pract Cases Emerg Med"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0190-9622(82)80200-4","article-title":"Trigeminal trophic syndrome. 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