{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T23:23:28Z","timestamp":1787354608569,"version":"build-2736575974"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>Background\u2002Endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD) is emerging as an alternative to choledochoduodenostomy (EUS-CDS) for malignant distal biliary obstruction (MDBO) after failed endoscopic retrograde cholangiopancreatography (ERCP). Comparative data on long-term patency are limited.<\/jats:p>\n                  <jats:p>Methods\u2002This retrospective international study analyzed two historical cohorts of patients who underwent EUS-GBD or EUS-CDS for MDBO after failed ERCP between March 2017 and May 2024.\u200aEligible patients were aged \u2265\u200a18 years with at least 6 months\u2019 follow-up or confirmed death. The primary outcome, after 1 : 1 propensity score matching, was 12-month biliary patency. Secondary outcomes included technical and clinical success, adverse events (AEs), reintervention rates, and overall survival.<\/jats:p>\n                  <jats:p>Results\u2002Before matching, 294 patients were included (142 EUS-GBD; 152 EUS-CDS). After matching, 200 patients were analyzed (100 per group). Technical success was 100\u200a% for EUS-GBD and 97\u200a% for EUS-CDS (P\u200a=\u200a0.25). Clinical success was 80.5\u200a% for EUS-GBD and 90.6\u200a% for EUS-CDS (P\u200a=\u200a0.08). At 12 months, the probability of biliary patency was significantly higher with EUS-GBD than EUS-CDS (86.2\u200a% [95\u200a%CI 74.2\u200a%\u201392.9\u200a%] vs. 63.8\u200a% [95\u200a%CI 49.5\u201375.0]; P\u200a=\u200a0.01). Biliary reintervention-free survival was significantly longer with EUS-GBD (log-rank, P\u200a&lt;\u200a0.001). Periprocedural AEs occurred in 7.0\u200a% vs. 10.0\u200a% (P\u200a=\u200a0.61), delayed AEs in 27.0\u200a% vs. 30.0\u200a% (P\u200a=\u200a0.75), and reintervention rates were comparable (23.0\u200a% vs. 26.0\u200a%; P\u200a=\u200a0.74). Overall survival did not differ significantly (log-rank, P\u200a=\u200a0.59).<\/jats:p>\n                  <jats:p>Conclusion\u2002In patients with MDBO after failed ERCP, EUS-GBD achieved higher 12-month biliary patency than EUS-CDS, with comparable rates of technical and clinical success, morbidity, reintervention, and overall survival.<\/jats:p>","DOI":"10.1055\/a-2837-9342","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T22:59:33Z","timestamp":1781650773000},"page":"978-988","source":"Crossref","is-referenced-by-count":2,"title":["CHOLEBLADEUS: long-term results of endoscopic ultrasound-guided gallbladder versus bile duct drainage of malignant biliary obstruction after failed ERCP: a propensity-matched study"],"prefix":"10.1055","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3785-6948","authenticated-orcid":false,"given":"Antoine","family":"Debourdeau","sequence":"first","affiliation":[{"name":"CHU N\u00eemes, N\u00eemes, France"},{"name":"Montpellier University, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00e9mie","family":"Albouys","sequence":"first","affiliation":[{"name":"Limoges University Hospital, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Privat","sequence":"additional","affiliation":[{"name":"Vichy Hospital, Vichy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carme","family":"Loras","sequence":"additional","affiliation":[{"name":"Hospital Universitari M\u00fatua de Terrassa, Terrassa and Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBEREHD), Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jules","family":"Daniel","sequence":"additional","affiliation":[{"name":"CHU N\u00eemes, N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Goudot","sequence":"additional","affiliation":[{"name":"Montpellier University, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Bourgaux","sequence":"additional","affiliation":[{"name":"CHU N\u00eemes, N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"Caillo","sequence":"additional","affiliation":[{"name":"CHU N\u00eemes, N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2984-5176","authenticated-orcid":false,"given":"Sergio","family":"Bazaga","sequence":"additional","affiliation":[{"name":"Hospital General de Granollers, Granollers, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2481-671X","authenticated-orcid":false,"given":"Pierre","family":"Mayer","sequence":"additional","affiliation":[{"name":"Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Legros","sequence":"additional","affiliation":[{"name":"Limoges University Hospital, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timoth\u00e9e","family":"Wallenhorst","sequence":"additional","affiliation":[{"name":"Rennes University Hospital, Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Schaefer","sequence":"additional","affiliation":[{"name":"Nancy University Hospital, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5866-8132","authenticated-orcid":false,"given":"Bertrand","family":"Napol\u00e9on","sequence":"additional","affiliation":[{"name":"H\u00f4pital Priv\u00e9 Jean Mermoz, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Leblanc","sequence":"additional","affiliation":[{"name":"H\u00f4pital Priv\u00e9 Jean Mermoz, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"G\u00e9rard","sequence":"additional","affiliation":[{"name":"CHU Lille, Service des Maladies de l\u2019Appareil Digestif, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick","family":"Moryoussef","sequence":"additional","affiliation":[{"name":"Poissy-Saint-Germain Hospital, Poissy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salom\u00e9","family":"Ouazana","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint Antoine (CRSA) & H\u00f4pital Saint Antoine, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2566-3866","authenticated-orcid":false,"given":"Marine","family":"Camus","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint Antoine (CRSA) & H\u00f4pital Saint Antoine, APHP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Williet","sequence":"additional","affiliation":[{"name":"Saint-Etienne University Hospital, Saint-Etienne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alban","family":"Benezech","sequence":"additional","affiliation":[{"name":"Avignon Hospital, Avignon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"Beaujon Hospital, Clichy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia Escuer","family":"Turu","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital; University of Barcelona; Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8857-3556","authenticated-orcid":false,"given":"Joan B.","family":"Gornals","sequence":"additional","affiliation":[{"name":"Bellvitge University Hospital; University of Barcelona; Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00e9mie","family":"Jacques","sequence":"additional","affiliation":[{"name":"Limoges University Hospital, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"and collaborators in the EUS-GBD Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1055\/a-0659-9864","article-title":"Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline\u202f \u2013 Updated October 2017","volume":"50","author":"J-M Dumonceau","year":"2018","journal-title":"Endoscopy"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1080\/00365521.2020.1867894","article-title":"Antibiotic prophylaxis in ERCP with failed cannulation","volume":"56","author":"G Olsson","year":"2021","journal-title":"Scand J 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