{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:10:04Z","timestamp":1778227804516,"version":"3.51.4"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100022274","name":"Daiichi Sankyo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100022274","id-type":"DOI","asserted-by":"crossref"}]},{"name":"AstraZeneca"},{"name":"Boston Scientific Corporation"},{"DOI":"10.13039\/100014421","name":"EA Pharma","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014421","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Takeda Pharmaceutical"},{"name":"National Cancer"},{"DOI":"10.13039\/100009734","name":"Olympus","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009734","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100013899","name":"FUJIFILM","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100013899","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Cancer Center Research and Development","award":["2024-A-15"],"award-info":[{"award-number":["2024-A-15"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Off-the-job training (OFF-JT) ensures that all trainees receive a standardized level of ESD training, regardless of the clinical workload or the regional context. This study aimed to evaluate the efficacy of OFF-JT using a next-generation laptop-based mock-up endoscopy simulator (NLMES) in improving endoscopic submucosal dissection (ESD) skills among international trainees.<\/jats:p>\n                  <jats:p>This study was a single-center, prospective pilot study employing a crossover design. International trainees in Group A underwent designated NLMES training and ESD observation during the early phase (Days 1\u201314), followed by ESD observation during the late phase (Days 15\u201328), whereas those in Group B followed the reverse schedule. On Days 1, 15, and 29, the trainees performed ESD using a biomaterial-free ESD model, and the ESD skills were assessed at each time point. The primary endpoint was the between-group comparison of improvement in dissection speed on Day 15.<\/jats:p>\n                  <jats:p>A total of 10 international trainees were enrolled in this study. On Day 15, the improvement in dissection speed was greater in Group A than in Group B, although the statistical difference was not significant (6.40 mm2\/min; 95% confidence interval [CI] 0.50\u201312.31] vs. -0.76 mm2\/min; 95% CI -8.91 to 7.39], P = 0.087). The within-group comparison of dissection speed between before and after NLMES training demonstrated significant differences in both groups.<\/jats:p>\n                  <jats:p>OFF-JT using NLMES might be a promising approach improving international trainee ESD skills. Dissection speed increased during the period when NLMES training was received, highlighting the importance of OFF-JT.<\/jats:p>","DOI":"10.1055\/a-2840-7240","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:22:40Z","timestamp":1774570960000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Efficacy of next-generation endoscopy training simulator in improving international trainee endoscopic submucosal dissection skills"],"prefix":"10.1055","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2115-8029","authenticated-orcid":false,"given":"Takeshi","family":"Uozumi","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2736-6921","authenticated-orcid":false,"given":"Seiichiro","family":"Abe","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]},{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Division of Science and Technology for Endoscopy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7827-3900","authenticated-orcid":false,"given":"Reona","family":"Kawamura","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Mizuguchi","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoji","family":"Ichijima","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Nonaka","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]},{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Division of Science and Technology for Endoscopy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhisa","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Nihon University School of Medicine, Japan","place":["Tokyo"],"department":["Department of Medicine, Division of Gastroenterology and Hepatology"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1909-3556","authenticated-orcid":false,"given":"Yutaka","family":"Saito","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Endoscopy Division"]},{"name":"National Cancer Center Hospital, Tokyo, Japan","place":["Chuo-ku"],"department":["Division of Science and Technology for Endoscopy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1136\/gut.48.2.225","article-title":"Endoscopic mucosal resection for treatment of early gastric cancer","volume":"48","author":"H Ono","year":"2001","journal-title":"Gut"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1053\/j.gastro.2021.02.036","article-title":"Endoscopic submucosal dissection in North America: A large prospective multicenter study","volume":"160","author":"PV Draganov","year":"2021","journal-title":"Gastroenterology"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1055\/s-0030-1256413","article-title":"Endoscopic submucosal dissection in a European setting. 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