{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:33:44Z","timestamp":1786120424946,"version":"build-2736575974"},"reference-count":40,"publisher":"Georg Thieme Verlag KG","issue":"05","funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82072773"],"award-info":[{"award-number":["82072773"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82203456"],"award-info":[{"award-number":["82203456"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82302627"],"award-info":[{"award-number":["82302627"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82472683"],"award-info":[{"award-number":["82472683"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"The Postdoctoral Research Fund, Sichuan University","award":["2024SCU12016"],"award-info":[{"award-number":["2024SCU12016"]}]},{"name":"The Postdoctoral Research Fund, West China Hospital, Sichuan University","award":["2023HXBH070"],"award-info":[{"award-number":["2023HXBH070"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pediatric meningiomas are extremely rare. The clinical features and prognosis of these patients remain unclear, especially due to the lack of large-scale clinical data.<\/jats:p>\n                  <jats:p>Pediatric and adult patients with meningiomas diagnosed between 2000 and 2021 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. The clinical characteristics (age, sex, race, tumor laterality, tumor behavior, treatment methods, etc.) of the included patients were reviewed, and the survival analysis was estimated via the Kaplan\u2012Meier method.<\/jats:p>\n                  <jats:p>A total of 364 pediatric patients were identified from the database. Pediatric meningiomas accounted for 0.2% to 0.6% of all meningiomas per year. The average age of pediatric patients was 12 years, and that of adult patients was 65 years. Adult meningioma patients were more commonly female, whereas no significant gender difference was observed in pediatric cases (p\u2009&lt;\u20090.001). Moreover, a higher proportion of borderline and malignant tumors was found in pediatric meningioma patients compared with adults (p\u2009&lt;\u20090.001). Survival analysis revealed that pediatric patients had a better survival prognosis than adult patients (p\u2009&lt;\u20090.001). Pediatric patients with coexisting tumors had a worse prognosis than those without coexisting tumors (p\u2009&lt;\u20090.001).<\/jats:p>\n                  <jats:p>This study comprehensively investigated the clinical features and survival outcomes of pediatric meningioma patients. Pediatric meningiomas are extremely uncommon and account for 0.2% to 0.6% of all meningiomas annually. Pediatric meningiomas have different clinical characteristics and better survival prognoses than those of adult patients.<\/jats:p>","DOI":"10.1055\/a-2846-3421","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T23:05:28Z","timestamp":1776121528000},"page":"338-345","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Features and Survival Outcomes of Pediatric Meningioma Patients: An Integrative Analysis Based on the SEER Database"],"prefix":"10.1055","volume":"87","author":[{"given":"Rui","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Li","sequence":"first","affiliation":[{"name":"Clinical Trial Center, National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Innovative Drugs, West China Hospital, Sichuan University, Chengdu, China"},{"name":"West China School of Nursing, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8099-0339","authenticated-orcid":false,"given":"Yanming","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuekang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4750-812X","authenticated-orcid":false,"given":"Xiaodong","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China"},{"name":"Department of Thoracic Surgery\/Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"issue":"S 03","key":"ref1","doi-asserted-by":"crossref","first-page":"iii1","DOI":"10.1093\/neuonc\/noae047","article-title":"CBTRUS Statistical Report: American Brain Tumor Association & NCI Neuro-Oncology Branch Adolescent and Young Adult Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2016-2020","volume":"26","author":"M Price","year":"2024","journal-title":"Neuro 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A review of advances in the treatment of meningiomas","volume":"10","author":"I Maggio","year":"2021","journal-title":"CNS Oncol"},{"issue":"01","key":"ref38","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/02688690701842208","article-title":"Children's Cancer and Leukaemia Group (CCLG): Guidelines for the management of intracranial meningioma in children and young people","volume":"22","author":"H Traunecker","year":"2008","journal-title":"Br J Neurosurg"},{"issue":"03","key":"ref39","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s11060-010-0368-5","article-title":"Fractionated radiotherapy for intracranial meningiomas","volume":"99","author":"V Gondi","year":"2010","journal-title":"J Neurooncol"},{"issue":"13","key":"ref40","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/S1470-2045(11)70275-3","article-title":"Meningiomas in children and adolescents: a meta-analysis of individual patient data","volume":"12","author":"R S Kotecha","year":"2011","journal-title":"Lancet Oncol"}],"container-title":["Journal of Neurological Surgery Part A: Central European Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2846-3421.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T22:41:01Z","timestamp":1786056061000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2846-3421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,13]]},"references-count":40,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2026,8,6]]},"published-print":{"date-parts":[[2026,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2846-3421","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2193-6315","2193-6323"],"issn-type":[{"value":"2193-6315","type":"print"},{"value":"2193-6323","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,4,13]]},"published":{"date-parts":[[2026,4,13]]}}}