{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:13:58Z","timestamp":1778109238188,"version":"3.51.4"},"reference-count":58,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Embolisation der Arteria meningea media (MMAE) ist eine relativ neue Option in der Behandlung des chronischen Subduralh\u00e4matoms (CSDH). Im Jahr 2000 erstmals bei Patienten mit CSDH unter ausgepr\u00e4gter Koagulopathie angewendet, liegen aktuell mehrere gro\u00dfe randomisierte kontrollierte Studien zur Wirksamkeit der MMAE vor. Ausgehend von einem komplexen pathophysiologischen Modell des CSDH mit Fokus auf Inflammation, Fibrinolyse und Neoangiogenese beruht der Effekt der MMAE auf dem Verschluss von pathologischen Gef\u00e4\u00dfen der Membranen des CSDH, deren Aktivit\u00e4t die Resorption eines CSDH verhindern. Die Embolisation der A. meningea media erfordert genaue Kenntnisse der individuellen Anatomie, da durch Fehlembolisation bei kritischen Kollateralen schwere unerw\u00fcnschte Wirkungen folgen k\u00f6nnen. Als Embolisat stehen prinzipiell Partikel, Fl\u00fcssigembolisate und Coils zur Verf\u00fcgung, wobei in den bisher ver\u00f6ffentlichten randomisierten kontrollierten Studien Partikel und Fl\u00fcssigembolisate zum Einsatz kamen. Basierend auf den letzten gro\u00dfen Studien wird die MMAE im interdisziplin\u00e4ren Konsens aktuell bei Patienten mit de novo CSDH und Kontraindikationen zur operativen Therapie sowie bei Patienten mit Rezidiv als Adjunkt zur herk\u00f6mmlichen Therapie empfohlen. Eine Vielzahl von weiteren Studien zur MMAE ist bereits registriert, sodass in absehbarer Zeit weitere Daten zu bisher unbeantworteten Fragen erwartet werden k\u00f6nnen.<\/jats:p>","DOI":"10.1055\/a-2851-9748","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T22:37:52Z","timestamp":1778107072000},"source":"Crossref","is-referenced-by-count":0,"title":["Embolisation der Arteria meningea media bei chronischen Subduralh\u00e4matomen"],"prefix":"10.1055","author":[{"given":"Arwed E","family":"Michael","sequence":"additional","affiliation":[{"name":"University Medical Center of the Johannes Gutenberg University Mainz Department of Neuroradiology, RP, Germany","place":["Mainz"],"department":["Department of Neuroradiology"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Behme","sequence":"additional","affiliation":[{"name":"Otto-von-Guericke-Universit\u00e4t Magdeburg, Sachsen-Anhalt, Germany","place":["Magdeburg"],"department":["University Clinic for Neuroradiology"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omid","family":"Nikoubashman","sequence":"additional","affiliation":[{"name":"University Hospital OWL, Campus Bielefeld-Bethel, University of Bielefeld, Germany","place":["Bielefeld"],"department":["Department of Diagnostic and Interventional Neuroradiology"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2908-7560","authenticated-orcid":false,"given":"Jan","family":"Borggrefe","sequence":"additional","affiliation":[{"name":"Ruhr University Bochum, Germany","place":["Minden"],"department":["University Institute of Radiology, Neuroradiology and Nuclear Medicine"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/0090-3019(94)90400-6","article-title":"Chronic subdural hematoma associated with middle meningeal arteriovenous fistula treated by a combination of embolization and burr hole drainage","volume":"42","author":"M Komiyama","year":"1994","journal-title":"Surg Neurol"},{"issue":"04","key":"ref2","doi-asserted-by":"publisher","first-page":"686","DOI":"10.3171\/jns.2000.93.4.0686","article-title":"Middle meningeal artery embolization for refractory chronic subdural hematoma. 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