{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:28:19Z","timestamp":1787272099714,"version":"build-2736575974"},"reference-count":58,"publisher":"Georg Thieme Verlag KG","issue":"03\/06","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":232,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100018693","name":"HORIZON EUROPE Framework Programme","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100019185","name":"HORIZON EUROPE Global Challenges and European Industrial Competitiveness","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100019185","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100018700","name":"HORIZON EUROPE Climate, Energy and Mobility","doi-asserted-by":"crossref","award":["101155958"],"award-info":[{"award-number":["101155958"]}],"id":[{"id":"10.13039\/100018700","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Methods Inf Med"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The invasive mosquito Aedes aegypti is a major vector of arboviruses, such as Dengue, Zika, Chikungunya and Yellow Fever.<\/jats:p>\n                  <jats:p>As a first step toward a transmission model for vector-borne diseases, a weather-dependent population dynamic simulation for Ae. aegypti was developed, suitable for high weather short-term variability in the Austrian region.<\/jats:p>\n                  <jats:p>We developed an agent-based model, incorporating temperature- and precipitation-dependent development, mortality, movement, feeding behavior, and egg-laying. Species-specific parameters were derived from published experimental studies. Simulations were run for observed weather data from 2024 and for EURO-CORDEX climate projections (\u00d6KS15) for 2050 and 2080 under RCP4.5 and RCP8.5. Daily immigration of one adult female was assumed to mimic human-mediated introduction along major transport routes.<\/jats:p>\n                  <jats:p>Under all scenarios, population development began in late May and ceased by late September. Observed 2024 conditions produced the highest population sizes (area under the curve [AUC]\u2009=\u2009361,343 individuals), whereas all future projections resulted in substantially lower abundances, despite higher mean temperatures.<\/jats:p>\n                  <jats:p>This discrepancy was driven by stronger fluctuations in temperature and precipitation, as well as the absence of urban heat-island effects in climate projections. Under no scenario did mosquitoes survive winter, indicating that long-term establishment is highly unlikely. The model provides a foundation for future extension toward spatially explicit virus transmission simulations, and for assessing the public health implications of climate change in alpine regions.<\/jats:p>","DOI":"10.1055\/a-2854-0579","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T22:55:26Z","timestamp":1776812126000},"page":"071-079","source":"Crossref","is-referenced-by-count":0,"title":["Agent-Based Modeling Approach for Population Dynamics of the Biological Vector Aedes Aegypti"],"prefix":"10.1055","volume":"64","author":[{"given":"Alexandra","family":"Schwaiger","sequence":"additional","affiliation":[{"name":"Division for Digital Health and Telemedicine, UMIT TIROL, Hall in Tirol, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Schweitzer","sequence":"additional","affiliation":[{"name":"Division for Digital Health and Telemedicine, UMIT TIROL, Hall in Tirol, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner O.","family":"Hackl","sequence":"additional","affiliation":[{"name":"Division for Digital Health and Telemedicine, UMIT TIROL, Hall in Tirol, Austria"},{"name":"Department of Clinical Epidemiology, Tirol Kliniken GmbH, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Pfeifer","sequence":"additional","affiliation":[{"name":"Division for Digital Health and Telemedicine, UMIT TIROL, Hall in Tirol, Austria"},{"name":"Department of Clinical Epidemiology, Tirol Kliniken GmbH, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"e1009590","DOI":"10.1371\/journal.ppat.1009590","article-title":"Frequency matters: How successive feeding episodes by blood-feeding insect vectors influences disease 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