{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:03:56Z","timestamp":1784588636240,"version":"3.55.0"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background The aim of this study was to evaluate the long-term treatment\n                    success and safety of ab externo canaloplasty in glaucoma patients.<\/jats:p>\n                  <jats:p>Methods and Material This study included 44 eyes undergoing canaloplasty.\n                    Patients were followed up at 2, 6, 12 months, 3 years and 5 years.<\/jats:p>\n                  <jats:p>Results The preoperative intraocular pressure (IOP) was 23.6\u2009\u00b1\u20096.4\u2009mmHg\n                    and was reduced to 15.8\u2009\u00b1\u20094.5\u2009mmHg at 12 months, 15.6\u2009\u00b1\u20093.8\u2009mmHg at 3 years and\n                    14.9\u2009\u00b1\u20093.9\u2009mmHg at 5 years after canaloplasty (p\u2009&lt;\u20090.0001). The relative IOP\n                    reduction was 33.6\u2009\u00b1\u200917.6% after 12 months, 30.4\u2009\u00b1\u200922.7% after 3\u00a0years and\n                    35.1\u2009\u00b1\u200917.7% after 5 years. Topical glaucoma medications were reduced from\n                    3.0\u2009\u00b1\u20091.3 to 1.2\u2009\u00b1\u20091.3 at 12 months, 1.3\u2009\u00b1\u20091.4 at 3 years and 1.2\u2009\u00b1\u20091.3 at 5\n                    years (p\u2009&lt;\u20090.0001). The complete surgical success rate (without topical\n                    glaucoma medications) was 32.3%, 26.9%, and 20.0% after 5 years for IOP\n                    &lt;\u200921\u2009mmHg, &lt;\u200918\u2009mmHg, and &lt;\u200916\u2009mmHg, respectively. The qualified\n                    surgical success (with topical glaucoma medications) was 72.0%, 65.8%, and\n                    43.1%, respectively. Six patients underwent 360\u00b0 trabeculotomy and five patients\n                    received laser Descemet puncture during the first 6 months after surgery.<\/jats:p>\n                  <jats:p>Conclusion Canaloplasty is a safe and effective procedure to achieve a\n                    significant reduction in IOP and glaucoma medications up to 5 years after\n                    surgery. Greater SC widths were associated with lower IOP values.<\/jats:p>","DOI":"10.1055\/a-2854-2826","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T23:03:17Z","timestamp":1782428597000},"page":"767-774","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the Long-term Success and Safety of Canaloplasty in\n                    Glaucoma Patients"],"prefix":"10.1055","volume":"243","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3473-7997","authenticated-orcid":false,"given":"Julia","family":"Prinz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, RWTH Aachen University,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Schellhase","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, RWTH Aachen University,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Fuest","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, RWTH Aachen University,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Walter","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, RWTH Aachen University,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Prokosch","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospital Cologne,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Plange","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, RWTH Aachen University,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kuerten","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, RWTH Aachen University,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1055\/a-2239-0290","article-title":"The Impact of Aging on the Function of Retinal Ganglion Cells","volume":"241","author":"J Prinz","year":"2024","journal-title":"Klin Monbl Augenheilkd"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: a\n                    systematic review and meta-analysis","volume":"121","author":"Y C 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