{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:58:36Z","timestamp":1791241116567,"version":"4.1.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T00:00:00Z","timestamp":1783382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Monkeypox (Mpox) is a viral infection that has shown increased global incidence, particularly affecting immunocompromised populations. We present a case of a 45-year-old human immunodeficiency virus (HIV)-positive man with progressive penile ulceration and necrosis. Mpox was confirmed via polymerase chain reaction testing of skin and oropharyngeal lesions. Despite antiviral therapy and antibiotics, the patient developed full-thickness necrosis of the penile shaft, scrotum, and suprapubic region. Surgical incision, drainage, and debridement were performed, followed by reconstruction using a pedicled anterolateral thigh flap. Secondary intention healing was selected for the penile shaft to preserve tissue elasticity and erectile function. The patient achieved complete wound healing within 3 months without complications. This case highlights a severe and rare manifestation of mpox in the setting of advanced HIV infection, emphasizing the importance of early diagnosis, multidisciplinary management, and tailored surgical planning to optimize both functional and aesthetic outcomes in immunocompromised patients.<\/jats:p>","DOI":"10.1055\/a-2856-5092","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:51:42Z","timestamp":1783464702000},"page":"395-401","source":"Crossref","is-referenced-by-count":0,"title":["Monkeypox-Associated Genital Necrosis in an Immunocompromised Patient: Case Report and Literature Review of Genital Mpox Reconstruction"],"prefix":"10.1055","volume":"53","author":[{"given":"Nae-Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Research Inst. of Clinical Medicine of Jeonbuk National University-Biomedical Research Inst. of Jeonbuk National Univ. Hospital, Jeonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2359-0272","authenticated-orcid":false,"given":"Beom Jin","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Research Inst. of Clinical Medicine of Jeonbuk National University-Biomedical Research Inst. of Jeonbuk National Univ. Hospital, Jeonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Yong","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Research Inst. of Clinical Medicine of Jeonbuk National University-Biomedical Research Inst. of Jeonbuk National Univ. Hospital, Jeonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon Kyu","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Research Inst. of Clinical Medicine of Jeonbuk National University-Biomedical Research Inst. of Jeonbuk National Univ. Hospital, Jeonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2865-0075","authenticated-orcid":false,"given":"Si-Gyun","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Research Inst. of Clinical Medicine of Jeonbuk National University-Biomedical Research Inst. of Jeonbuk National Univ. Hospital, Jeonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,7,7]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jiph.2023.02.003","article-title":"Monkeypox (mpox) virus: classification, origin, transmission, genome organization, antiviral drugs, and molecular diagnosis","volume":"16","author":"A Karagoz","year":"2023","journal-title":"J Infect Public Health"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/s41392-023-01675-2","article-title":"Mpox (formerly monkeypox): pathogenesis, prevention, and treatment","volume":"8","author":"J Lu","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"08","key":"ref3","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1056\/NEJMoa2207323","article-title":"Monkeypox virus infection in humans across 16 countries - April-June 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sufficient for the treatment of Mpox (monkeypox) in advanced HIV patients with a low CD4 cell count?","volume":"96","author":"J H Hwang","year":"2024","journal-title":"J Med Virol"},{"issue":"05","key":"ref8","doi-asserted-by":"crossref","first-page":"e190","DOI":"10.1016\/S1473-3099(22)00869-6","article-title":"Novel severe oculocutaneous manifestations of human monkeypox virus infection and their historical analogues","volume":"23","author":"S Carrubba","year":"2023","journal-title":"Lancet Infect Dis"},{"issue":"08","key":"ref9","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/hiv.13622","article-title":"The effect of HIV and mpox co-infection on clinical outcomes: systematic review and meta-analysis","volume":"25","author":"A M Taha","year":"2024","journal-title":"HIV Med"},{"issue":"02","key":"ref10","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/1346-8138.17605","article-title":"Atypical mucocutaneous manifestations of Mpox: a systematic 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Spyropoulou","year":"2013","journal-title":"Urology"},{"issue":"12","key":"ref20","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/S1473-3099(23)00427-9","article-title":"Clinical characteristics and predictors of human mpox outcome during the 2022 outbreak in Nigeria: a cohort study","volume":"23","author":"D Ogoina","year":"2023","journal-title":"Lancet Infect Dis"},{"issue":"08","key":"ref21","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jiac.2024.01.004","article-title":"Human mpox presenting with penile edema and ulcer: a case report","volume":"30","author":"Y Miyazaki","year":"2024","journal-title":"J Infect Chemother"},{"issue":"02","key":"ref22","first-page":"e78509","article-title":"Necrotizing fasciitis as a novel complication of penile edema in a patient with monkeypox: a case report","volume":"17","author":"S S Gawargeous","year":"2025","journal-title":"Cureus"},{"issue":"10","key":"ref23","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/cup.14499","article-title":"Disseminated and penile mpox with histopathologic correlation: two separate case reports","volume":"50","author":"S S Koh","year":"2023","journal-title":"J Cutan Pathol"},{"issue":"09","key":"ref24","first-page":"e92052","article-title":"Mpox in a gynecological setting: a case report","volume":"17","author":"Y Abrefa Safo","year":"2025","journal-title":"Cureus"},{"issue":"04","key":"ref25","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/DAD.0000000000002643","article-title":"Mpox case presenting with genital lesions and proctitis","volume":"46","author":"Y Alhalaseh","year":"2024","journal-title":"Am J Dermatopathol"}],"container-title":["Archives of Plastic 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