{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T08:35:26Z","timestamp":1793262926271,"version":"4.5.0"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"09","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020192","name":"Medtronic Europe","doi-asserted-by":"crossref","award":["ESGE (European Society of Gastrointestinal Endoscopy)"],"award-info":[{"award-number":["ESGE (European Society of Gastrointestinal Endoscopy)"]}],"id":[{"id":"10.13039\/100020192","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The effect of computer-aided detection (CADe) on performance of endoscopists with different experience levels is not well understood. This study assessed whether CADe use promotes learning or deskilling.<\/jats:p>\n                  <jats:p>We performed a prospective, multicenter, registry-based, pragmatic clinical trial. The primary end point was change in the proportion of colonoscopies with detection of at least one polyp \u22655 mm (PDR-5). Each endoscopist performed colonoscopies in three successive phases: 1) before CADe exposure, 2) during CADe use, and 3) after CADe removal. To assess the impact of CADe on PDR-5, we compared phase 1 with phases 2 and 3, adjusting for patient and endoscopist characteristics and endoscopy performance measures. Generalized linear mixed models were used and presented according to endoscopist experience.<\/jats:p>\n                  <jats:p>13 endoscopists (7 inexperienced, 6 experienced) performed 5013 colonoscopies; median patient age was 59 years (interquartile range 44\u201371) and 2703 (53.9%) were women. Patient sex and age were similar across the two experience groups, whereas indications differed (e.g. more inflammatory bowel disease in the inexperienced group). CADe temporarily increased PDR-5 among inexperienced endoscopists from phase 1 to 2 (31.9% [216\/678] to 39.5% [257\/651]; odds ratio [OR] 1.43, 95%CI 1.11\u20131.84). There was no significant change between phases 1 and 3 (31.9% [216\/678] to 36.3% [173\/476]; OR 1.03, 95%CI 0.79\u20131.34). There was no significant CADe effect on PDR-5 among experienced endoscopists between phases.<\/jats:p>\n                  <jats:p>PDR-5 of inexperienced endoscopists increased when CADe was used. In non-CADe-assisted colonoscopy, no upskilling or deskilling was observed following a period of CADe exposure.<\/jats:p>","DOI":"10.1055\/a-2858-7084","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:46:08Z","timestamp":1780526768000},"page":"1003-1014","source":"Crossref","is-referenced-by-count":7,"title":["Learning and deskilling effects of artificial intelligence in colonoscopy among endoscopists with different levels of experience: a pragmatic, prospective trial"],"prefix":"10.1055","volume":"58","clinical-trial-number":[{"clinical-trial-number":"nct05322993","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0290-0567","authenticated-orcid":false,"given":"Tom Andre","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Haukeland University Hospital, Norway","place":["Bergen"],"department":["Department of Medicine"]},{"name":"Haraldsplass Deaconess Hospital, Norway","place":["Bergen"],"department":["Department of Medicine"]},{"name":"University of Bergen, Norway","place":["Bergen"],"department":["Bergen Research Group for Advanced Gastrointestinal Endoscopy (BRAGE), Department of Clinical Medicine (K1)"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2262-0334","authenticated-orcid":false,"given":"Yuichi","family":"Mori","sequence":"additional","affiliation":[{"name":"University of Oslo, Norway","place":["Oslo"],"department":["Clinical Effectiveness Research Group"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Botteri","sequence":"additional","affiliation":[{"name":"Cancer Registry of Norway, Norwegian Institute of Public Health, Norway","place":["Oslo"],"department":["Department of Colorectal Cancer Screening"]},{"name":"Cancer Registry of Norway, Norwegian Institute of Public Health, Norway","place":["Oslo"],"department":["Department of Research"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trond","family":"Engjom","sequence":"additional","affiliation":[{"name":"Haukeland University Hospital, Norway","place":["Bergen"],"department":["Department of Medicine"]},{"name":"University of Bergen, Norway","place":["Bergen"],"department":["Department of Clinical Medicine (K1)"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitte","family":"Seip","sequence":"additional","affiliation":[{"name":"Vestfold Hospital Trust, Norway","place":["T\u00f8nsberg"],"department":["Department of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg Gjorgji","family":"Dimcevski","sequence":"additional","affiliation":[{"name":"Kanalspesialistene AS, Norway","place":["Bergen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roald Flesland","family":"Havre","sequence":"additional","affiliation":[{"name":"Haukeland University Hospital, Norway","place":["Bergen"],"department":["Department of Medicine"]},{"name":"University of Bergen, Norway","place":["Bergen"],"department":["Bergen Research Group for Advanced Gastrointestinal Endoscopy (BRAGE), Department of Clinical Medicine (K1)"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1056\/NEJMoa0907667","article-title":"Quality indicators for colonoscopy and the risk of interval cancer","volume":"362","author":"MF Kaminski","year":"2010","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1056\/NEJMoa1309086","article-title":"Adenoma detection rate and risk of colorectal cancer and death","volume":"370","author":"DA Corley","year":"2014","journal-title":"N Engl J 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Troya","year":"2024","journal-title":"Endoscopy"}],"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2858-7084.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T22:35:41Z","timestamp":1787351741000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2858-7084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,3]]},"references-count":32,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2026,8,21]]},"published-print":{"date-parts":[[2026,9]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2858-7084","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,3]]}}}