{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:04:11Z","timestamp":1784588651230,"version":"3.55.0"},"reference-count":89,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Das akute Lungenversagen (ARDS) geh\u00f6rt zu den komplexesten Krankheitsbildern der Intensivmedizin und stellt Kliniker*innen durch seine Heterogenit\u00e4t t\u00e4glich vor neue Herausforderungen. Mit einer Mortalit\u00e4t von 35\u201345% bleibt es eine bedeutsame klinische Herausforderung, doch aktuelle Entwicklungen er\u00f6ffnen vielversprechende Therapieoptionen.Die moderne ARDS-Behandlung entwickelt sich stetig weiter: Parameter wie Driving Pressure und Mechanical Power erg\u00e4nzen bew\u00e4hrte Konzepte der lungenprotektiven Beatmung und erm\u00f6glichen eine pr\u00e4zisere Therapiesteuerung. Transpulmonale Druckmessung unterst\u00fctzt die individuelle PEEP-Titration, w\u00e4hrend automatisierte Regelkreissysteme die Zeit in lungenprotektiven Bereichen signifikant verl\u00e4ngern k\u00f6nnen.Die VV-ECMO hat sich als wichtige Rescue-Therapie etabliert und erh\u00e4lt in der neuen S3-Leitlinie 2025 erstmals eine konditionelle Empfehlung. Ultraprotektive Beatmungsstrategien unter ECMO erm\u00f6glichen eine deutliche Reduktion der mechanischen Belastung und unterst\u00fctzen das Konzept des \u201elung rest\u201c.Von der Epidemiologie und Pathophysiologie \u00fcber neue Krankheitsbilder wie EVALI bis zu innovativen Monitoringverfahren \u2013 dieser \u00dcbersichtsartikel bietet einen aktuellen \u00dcberblick \u00fcber die Grundlagen des Syndroms wie auch die moderne Diagnostik und Therapie des ARDS und zeigt, wie sich diese Erkenntnisse gewinnbringend in der t\u00e4glichen Praxis umsetzen lassen.<\/jats:p>","DOI":"10.1055\/a-2867-9658","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T22:39:08Z","timestamp":1780439948000},"page":"500-513","source":"Crossref","is-referenced-by-count":0,"title":["Akutes Lungenversagen"],"prefix":"10.1055","volume":"80","author":[{"given":"Ulrike","family":"Olgem\u00f6ller","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin G\u00f6ttingen, Deutschland","place":["G\u00f6ttingen"],"department":["Klinik f\u00fcr Kardiologie und Pneumologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Becker","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin G\u00f6ttingen, Deutschland","place":["G\u00f6ttingen"],"department":["Klinik f\u00fcr Kardiologie und Pneumologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars-Olav","family":"Harnisch","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin G\u00f6ttingen, Deutschland","place":["G\u00f6ttingen"],"department":["Klinik f\u00fcr An\u00e4sthesiologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/s0140-6736(67)90168-7","article-title":"Acute respiratory distress in adults","volume":"2","author":"DG 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