{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:06:55Z","timestamp":1779408415821,"version":"3.53.1"},"reference-count":4,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study aimed to compare temporal trends in congenital syphilis with adult primary and secondary syphilis incidence in Texas, United States.<\/jats:p>\n                  <jats:p>Population-based retrospective trend analysis using Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research data from 2016 to 2023.<\/jats:p>\n                  <jats:p>Congenital syphilis incidence increased from 17.5 to 238.6 per 100,000 live births, representing a 12.6-fold increase. The annual percent change (APC) was 29.7% (95% CI: 27.9\u201331.6; p\u2009&lt;\u20090.001). Adult primary and secondary syphilis increased from 7.0 to 15.0 per 100,000 population (113% increase), with an APC of 13.1% (95% CI: 12.5\u201313.8; p\u2009&lt;\u20090.001). The increase in congenital syphilis significantly outpaced adult trends (interaction p\u2009&lt;\u20090.001).<\/jats:p>\n                  <jats:p>Congenital syphilis in Texas, United States, has increased at a markedly greater rate than adult syphilis, suggesting failures in prenatal screening, treatment, or care access beyond rising community transmission alone.<\/jats:p>","DOI":"10.1055\/a-2869-3893","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T22:43:08Z","timestamp":1778107388000},"source":"Crossref","is-referenced-by-count":0,"title":["Disproportionate Rise in Congenital Syphilis Compared with Adult Syphilis Trends in Texas, United States: A Population-Based Analysis, 2016-2023"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4865-6255","authenticated-orcid":false,"given":"Diana","family":"Toro","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Health San Antonio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Chiu","sequence":"additional","affiliation":[{"name":"Long School of Medicine, University of Texas Health San Antonio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila","family":"Alkassar","sequence":"additional","affiliation":[{"name":"Long School of Medicine, University of Texas Health San Antonio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Stansbury","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, University of Texas Health San Antonio, UT Health San Antonio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"key":"ref1","volume-title":"Sexually Transmitted Infections Surveillance, 2023","author":"Centers for Disease Control and Prevention","year":"2024"},{"key":"ref2","first-page":"85","volume-title":"Sexually Transmitted Infections Surveillance, 2023","author":"Centers for Disease Control and Prevention","year":"2024"},{"issue":"44","key":"ref3","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.15585\/mmwr.mm6444a3","article-title":"Increase in incidence of congenital syphilis - United States, 2012-2014","volume":"64","author":"V Bowen","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.ajog.2016.11.1052","article-title":"Syphilis during pregnancy: a preventable threat to maternal-fetal health","volume":"216","author":"M W Rac","year":"2017","journal-title":"Am J Obstet Gynecol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2869-3893.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T23:08:34Z","timestamp":1779404914000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2869-3893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,6]]},"references-count":4,"URL":"https:\/\/doi.org\/10.1055\/a-2869-3893","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,5,6]]},"published":{"date-parts":[[2026,5,6]]}}}