{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T23:26:56Z","timestamp":1786577216084,"version":"build-2736575974"},"reference-count":130,"publisher":"Georg Thieme Verlag KG","issue":"08","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geburtshilfe Frauenheilkd"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Objective The aim of the German-language S3 guideline on lichen sclerosus (LS) is to provide an evidence- and consensus-based foundation for the diagnosis and management of this disease. The present publication offers a concise summary of the relevant content, focusing on genital LS in girls and women. This first part addresses, among other aspects, the definition, symptomatology, and diagnosis of LS, as well as its management during pregnancy. The separately published second part focuses on the treatment of LS.<\/jats:p>\n                  <jats:p>Methods The German-language, evidence- and consensus-based S3 guideline on LS was developed under the leadership of the German Society of Gynecology and Obstetrics (DGGG) and the German Dermatological Society (DDG), based on the European \u201cEuroGuiDerm Guideline on Lichen Sclerosus.\u201d The interdisciplinary guideline panel included 24 experts from 16\u00a0professional societies and actively involved patient representatives in the development process.<\/jats:p>\n                  <jats:p>Recommendations LS is a chronic inflammatory skin disease with predominant manifestation in the anogenital region. It may be associated with pruritus, pain, sexual dysfunction, urinary symptoms, and constipation, although it can occasionally remain asymptomatic. Awareness of the broad spectrum of symptoms, as well as reversible and irreversible clinical signs, is essential to enable early diagnosis and appropriate treatment. Early and adequate therapy can not only alleviate symptoms but also reduce the risk of permanent damage and the development of associated carcinomas. During pregnancy, treatment with topical glucocorticoids should be continued as needed to control disease activity and prevent complications.<\/jats:p>","DOI":"10.1055\/a-2871-3377","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T22:32:15Z","timestamp":1786573935000},"page":"693-719","source":"Crossref","is-referenced-by-count":0,"title":["Lichen sclerosus. Part 1. Guideline of the DGG, DGGG, OEGGG and SGGG (S3-Level, AWMF Registry No.\u2009013-105, July 2025"],"prefix":"10.1055","volume":"86","author":[{"given":"Gudula","family":"Kirtschig","sequence":"additional","affiliation":[{"name":"Medbase Health Centre Frauenfeld, Frauenfeld, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"G\u00fcnthert","sequence":"additional","affiliation":[{"name":"gyn-zentrum Luzern Cham Kriens, Luzern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Kinberger","sequence":"additional","affiliation":[{"name":"Division of Evidence-Based Medicine (dEBM), Klinik f\u00fcr Dermatologie, Venerologie und Allergologie, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Becker","sequence":"additional","affiliation":[{"name":"Kinderchirurgische Praxis Bonn, Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Ciresa-K\u00f6nig","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Gyn\u00e4kologie und Geburtshilfe, Med. Universit\u00e4t, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Fischer","sequence":"additional","affiliation":[{"name":"Verein Lichen sclerosus Schweiz, Dottikon, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Fricke-Otto","sequence":"additional","affiliation":[{"name":"P\u00e4diatrische Endokrinologie und Diabetologie, Kindernotaufnahme, Kinderschutzteam Helios-Klinikum Krefeld, Krefeld, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"G\u00fcnther","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Carl Gustav Carus Dresden, Klinik und Poliklinik f\u00fcr Dermatologie, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Hirchenhain","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Carl Gustav Carus Dresden, Klinik und Poliklinik f\u00fcr Frauenheilkunde und Geburtshilfe, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narayani Helga","family":"K\u00f6llmann","sequence":"additional","affiliation":[{"name":"Verein Lichen sclerosus Schweiz, Dottikon, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Kreuter","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Dermatologie, Venerologie und Allergologie, Helios St.\u00a0Elisabeth Klinik Oberhausen, Oberhausen, Germany"},{"name":"Klinik f\u00fcr Dermatologie, Venerologie und Allergologie, Helios St.\u00a0Johannes Klinik Duisburg, Duisburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bartosz","family":"Malisiewicz","sequence":"additional","affiliation":[{"name":"Main Medic. 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