{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:48:42Z","timestamp":1782258522309,"version":"3.54.5"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background and study aims Accurate measurement of colorectal polyp size is important for planning resection and post-polypectomy surveillance. This study evaluated a through-the-scope laser-based probe for polyp sizing during colonoscopy.<\/jats:p>\n                  <jats:p>Patients and methods A prospective pilot study was conducted at CHUM, where polyps were measured using a laser-based probe. The primary outcome was accuracy of the laser-based probe, defined as mean bias with microscopic sizing as the reference standard. Secondary outcomes included agreement with the reference, implementation rate, technical success rate, reasons for failure, and per-polyp measurement time.<\/jats:p>\n                  <jats:p>Results Among 323 patients, 402 colorectal polyps were detected. Laser-based measurement was attempted in 237 polyps (59.0% 237\/402; 95% confidence interval [CI] 54.0\u201363.8), of which 149 had microscopic reference measurements. The technical success rate was 40.9% (97\/237; 95% CI 34.6\u201347.5), with a mean measurement time of 1:35. Accounting for non-en-bloc resections, 41 of 149 polyps (27.5%; 95% CI 20.7\u201335.5) had paired laser-microscopy measurements for the primary analysis. Laser-based measurement showed minimal bias (\u22120.10 mm; 95% CI \u22120.30 to 0.10; P = 0.328), meeting the prespecified noninferiority margin of 0.4 mm. Agreement with the reference standard was high (intraclass correlation coefficient = 0.91; 95% CI 0.83\u20130.95), with near-perfect categorical concordance (\u03ba = 0.85) and 95.1% classification accuracy (39\/41; 95% CI 82.2\u201399.2). Bland\u2013Altman limits of agreement ranged from \u22121.34 to 1.14 mm.<\/jats:p>\n                  <jats:p>Conclusions Laser-based measurement provided accurate polyp sizing when obtained. However, technical success was limited by longer measurement times and device issues.<\/jats:p>","DOI":"10.1055\/a-2872-7167","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T23:36:22Z","timestamp":1778283382000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Endoscopic Polyp Size Measurement Using a Laser-Based Sizing Probe: Pilot Study"],"prefix":"10.1055","volume":"14","author":[{"given":"Mohamed Zineddine","family":"Mahdadi","sequence":"additional","affiliation":[{"name":"Centre Hospitalier de l\u2019Universite de Montr\u00e9al, Canada","place":["Montreal"],"department":["Medicine"]},{"name":"University of Montreal, Canada","place":["Montreal"],"department":["Hospital Research Center (CRCHUM)"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9ric","family":"Cristea","sequence":"additional","affiliation":[{"name":"Centre Hospitalier de l\u2019Universite de Montr\u00e9al, 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