{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:01:08Z","timestamp":1790640068551,"version":"4.1.0"},"reference-count":67,"publisher":"Georg Thieme Verlag KG","issue":"11","funder":[{"name":"CAPES","award":["Finance Code 001. CNPq (National Council for Scientific and Technological Development\u2014Brazil)."],"award-info":[{"award-number":["Finance Code 001. CNPq (National Council for Scientific and Technological Development\u2014Brazil)."]}]},{"name":"FAPESP (Sao Paulo Research Foundation\u2014process number:","award":["2018\/22593-7; 2020\/01968-2)"],"award-info":[{"award-number":["2018\/22593-7; 2020\/01968-2)"]}],"id":[{"id":"https:\/\/ror.org\/02ddkpn78","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The aim of this study was to analyze, among lean adolescents, the changes in lipids associated with sports participation and the role of time spent in vigorous sports participation. Lean adolescents of both sexes were followed for 12 months (121 boys and 51 girls [aged 11\u201317 y]). Lipids were the dependent variables (total cholesterol, low density lipoprotein-cholesterol, high density lipoprotein-cholesterol, triacylglycerol and the atherogenic index of plasma). Adolescents were divided according to sports participation (engaged and not engaged), with sports participation intensity assessed by heart rate during sports. Multivariate models were adjusted by ethnicity, biological maturation, body fat, lean soft tissue, insulin resistance, and inflammation. The atherogenic index of plasma changed in favor of boys (engaged: \u22120.021 [95% confidence interval: \u22120.060 to 0.019] versus not engaged: 0.117 [95% confidence interval: 0.028 to 0.207]) and girls engaged in sports (engaged: \u22120.062 [95% confidence interval: \u22120.102 to \u22120.022] versus not engaged: 0.098 [95% confidence interval: \u22120.018 to 0.214]). The main determinants of changes in the atherogenic index of plasma among boys were changes in lean soft tissue (r=\u22120.415 and p=0.050) and vigorous physical activity among girls (r=\u22120.291 and p=0.012). In summary, sports participation was associated with improvements in lipid profile among lean adolescents.<\/jats:p>","DOI":"10.1055\/a-2882-1662","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T22:51:39Z","timestamp":1781218299000},"page":"820-828","source":"Crossref","is-referenced-by-count":0,"title":["Vigorous Sports Participation and Plasma Lipids in Lean Adolescents: ABCD Growth Study"],"prefix":"10.1055","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0733-5618","authenticated-orcid":false,"given":"Ana Elisa","family":"von Ah Morano","sequence":"additional","affiliation":[{"name":"Laboratory of Investigation in Exercise (LIVE), Department of Physical Education, Sao Paulo State University \u2014 UNESP, Sao Paulo, Brazil","place":["Presidente Prudente"]},{"name":"Public Health and Sport Sciences, University of Exeter, UK","place":["Exeter"],"department":["Children\u2019s Health and Exercise Research Centre"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6990-3596","authenticated-orcid":false,"given":"Jeff S.","family":"Coombes","sequence":"additional","affiliation":[{"name":"The University of Queensland, Queensland, Australia","place":["Brisbane"],"department":["School of Human Movement and Nutrition Sciences"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1576-8090","authenticated-orcid":false,"given":"Romulo","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Laboratory of Investigation in Exercise (LIVE), Department of Physical Education, Sao Paulo State University \u2014 UNESP, Sao Paulo, Brazil","place":["Presidente Prudente"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"4176","DOI":"10.3390\/nu13114176","article-title":"Obesity and cardiometabolic risk factors: From childhood to adulthood","volume":"13","author":"D Drozdz","year":"2021","journal-title":"Nutrients"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.ecl.2022.02.002","article-title":"Evaluation and management of lipids and lipoproteins in children and adolescents","volume":"51","author":"A Patel","year":"2022","journal-title":"Endocrinol Metab Clin North Am"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.pcad.2022.11.004","volume-title":"The associations between exercise and lipid biomarkers","author":"R M Sulague","year":"2022"},{"issue":"06","key":"ref4","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1249\/MSS.0000000000001934","article-title":"High-intensity interval training for cardiometabolic disease prevention","volume":"51","author":"W W Campbell","year":"2019","journal-title":"Med Sci Sports Exerc"},{"issue":"11","key":"ref5","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/j.jsams.2022.08.002","article-title":"Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?","volume":"25","author":"E A Haapala","year":"2022","journal-title":"J Sci Med Sport"},{"issue":"07","key":"ref6","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1249\/MSS.0b013e318213fefb","article-title":"Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: Guidance for prescribing exercise","volume":"43","author":"C E Garber","year":"2011","journal-title":"Med Sci Sports Exerc"},{"issue":"04","key":"ref7","doi-asserted-by":"publisher","first-page":"e2021050810","DOI":"10.1542\/peds.2021-050810","article-title":"High-intensity interval training and cardiometabolic risk factors in children: A meta-analysis","volume":"148","author":"M Solera-Mart\u00ednez","year":"2021","journal-title":"Pediatrics"},{"issue":"06","key":"ref8","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1016\/j.jpeds.2005.01.055","article-title":"Evidence based physical activity for school-age youth","volume":"146","author":"W B Strong","year":"2005","journal-title":"Journal of Pediatrics"},{"issue":"07","key":"ref9","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1080\/17461391.2022.2098057","article-title":"Longitudinal association between moderate to vigorous physical activity and lipid profile indicators in adolescents","volume":"23","author":"A O Barbosa","year":"2023","journal-title":"Eur J Sport Sci"},{"issue":"05","key":"ref10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/ajhb.23387","article-title":"Sports participation improves metabolic profile in adolescents: ABCD growth study","volume":"32","author":"S U Cayres-Santos","year":"2020","journal-title":"Am J Hum Biol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1152\/japplphysiol.00663.2011.-Purpose","article-title":"High-intensity training improves airway responsiveness in inactive nonasthmatic children: Evidence from a randomized controlled trial","volume":"112","author":"S K Rosenkranz","year":"2012","journal-title":"J Appl Physiol"},{"issue":"01","key":"ref12","doi-asserted-by":"publisher","first-page":"16888","DOI":"10.1038\/s41598-022-21262-9","article-title":"Prevalence and factors associated with dyslipidemia among adolescents in Saudi Arabia","volume":"12","author":"S AlMuhaidib","year":"2022","journal-title":"Sci Rep"},{"issue":"05","key":"ref13","doi-asserted-by":"publisher","first-page":"e70060","DOI":"10.1002\/ajhb.70060","article-title":"Participants and non-participants in organized sports 11\u201314 years: Growth, maturity status, physical activity, motor coordination and physical fitness","volume":"37","author":"R M Malina","year":"2025","journal-title":"Am J Hum Biol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/s1054-139x(02)00485-8","article-title":"Growth at puberty","volume":"31","author":"A D Rogol","year":"2002","journal-title":"J Adolesc Health"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/72.5.1307s","volume-title":"Origin of atherosclerosis in childhood and adolescence","author":"J McGill","year":"2000"},{"issue":"01","key":"ref16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s12966-015-0274-5","article-title":"Objectively measured physical activity and sedentary time in youth: The International children\u2019s accelerometry database (ICAD)","volume":"12","author":"A R Cooper","year":"2015","journal-title":"Int Behav Nutr Phys Act"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1016\/j.jadohealth.2019.03.013","article-title":"Tracking of physical activity and sedentary behavior from adolescence to young adulthood: A systematic literature review","volume":"65","author":"G Hayes","year":"2019","journal-title":"J Adolesc Health"},{"issue":"01","key":"ref18","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1186\/s12966-015-0237-x","article-title":"Number of years of participation in some, but not all, types of physical activity during adolescence predicts level of physical activity in adulthood: Results from a 13-year study","volume":"12","author":"M B\u00e9langer","year":"2015","journal-title":"Int J Behav Nutr Phys Act"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"474","DOI":"10.21037\/tp-21-507","article-title":"Tracking of physical fitness levels from childhood and adolescence to adulthood: A systematic review and meta-analysis","volume":"11","author":"A Garc\u00eda-Hermoso","year":"2022","journal-title":"Transl Pediatr"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.ypmed.2016.11.027","article-title":"Global participation in sport and leisure-time physical activities: A systematic review and meta-analysis","volume":"95","author":"R M Hulteen","year":"2017","journal-title":"Prev Med (Baltim)"},{"issue":"10","key":"ref21","doi-asserted-by":"publisher","first-page":"6235","DOI":"10.3390\/ijerph19106235","article-title":"Physical activity and sports participation among adolescents: Associations with sports-related knowledge and attitudes","volume":"19","author":"L Oja","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"S197","DOI":"10.1139\/apnm-2015-0663","article-title":"Systematic review of the relationships between objectively measured physical activity and health indicators in school-aged children and youth","volume":"41","author":"V J Poitras","year":"2016","journal-title":"Appl Physiol Nutr Metab"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"891906","DOI":"10.3389\/fpsyg.2022.891906","article-title":"Editorial: Advances in sport science: Latest findings and new scientific proposals","volume":"13","author":"R Maneiro","year":"2022","journal-title":"Front Psychol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"1081675","DOI":"10.3389\/fcvm.2023.1081675","article-title":"Cardiovascular health and potential cardiovascular risk factors in young athletes","volume":"10","author":"C Grabitz","year":"2023","journal-title":"Front Cardiovasc Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"53","DOI":"10.2217\/cer.12.74","article-title":"Pros and cons of pragmatic clinical trials","volume":"2","author":"J D Lurie","year":"2013","journal-title":"J Comp Eff Res"},{"issue":"05","key":"ref26","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.jclinepi.2008.12.011","article-title":"A pragmatic-explanatory continuum indicator summary (PRECIS): A tool to help trial designers","volume":"62","author":"K E Thorpe","year":"2009","journal-title":"J Clin Epidemiol"},{"issue":"01","key":"ref27","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1080\/02640418708729763","article-title":"Standard score assessment on physique and performance of brazilian athletes in a six tiered competitive sports model","volume":"5","author":"VK R Matsudo","year":"1987","journal-title":"J Sports Sci"},{"issue":"03","key":"ref28","doi-asserted-by":"publisher","first-page":"358","DOI":"10.2105\/ajph.82.3.358","article-title":"Body fatness and risk for elevated blood pressure, total cholesterol, and serum lipoprotein ratios in children and adolescents","volume":"82","author":"D P Williams","year":"1992","journal-title":"Am J Public Health"},{"issue":"03","key":"ref29","doi-asserted-by":"publisher","first-page":"358","DOI":"10.2105\/ajph.82.3.358","article-title":"Body fatness and risk for elevated blood pressure, total cholesterol, and serum lipoprotein ratios in children and adolescents","volume":"82","author":"D P Williams","year":"1992","journal-title":"Am J Public Health"},{"issue":"12","key":"ref30","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.2337\/diacare.21.12.2191","article-title":"Correct homeostasis model assessment (HOMA) evaluation uses the computer program","volume":"21","author":"J C Levy","year":"1998","journal-title":"Diabetes Care"},{"issue":"07","key":"ref31","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/s0009-9120(01)00263-6","article-title":"The plasma parameter log (TG\/HDL-C) as an atherogenic index: Correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER(HDL))","volume":"34","author":"M Dobi\u00e1sov\u00e1","year":"2001","journal-title":"Clin Biochem"},{"issue":"06","key":"ref32","doi-asserted-by":"publisher","first-page":"e20190997","DOI":"10.1542\/peds.2019-0997","article-title":"Organized sports for children, preadolescents, and adolescents","volume":"143","author":"K Logan","year":"2019","journal-title":"Pediatrics"},{"issue":"11","key":"ref33","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1016\/j.jsams.2019.06.012","article-title":"Validity of the polar team pro sensor for measuring speed and distance indoors","volume":"22","author":"J L Fox","year":"2019","journal-title":"J Sci Med Sport"},{"issue":"05","key":"ref34","doi-asserted-by":"publisher","first-page":"303","DOI":"10.2165\/00007256-198805050-00002","article-title":"Heart rate and exercise intensity during sports activities","volume":"5","author":"J Karvonen","year":"1988","journal-title":"Pract Appl Sports Med"},{"issue":"01","key":"ref35","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1186\/s12887-017-0868-.","article-title":"Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish\/North-European White children and adolescents","volume":"17","author":"TR H Nielsen","year":"2017","journal-title":"BMC Pediatr"},{"issue":"03","key":"ref36","doi-asserted-by":"publisher","first-page":"252","DOI":"10.2223\/JPED.2093","article-title":"Associa\u00e7\u00e3o transversal entre h\u00e1bitos alimentares saud\u00e1veis e n\u00e3o saud\u00e1veis e atividade f\u00edsica de lazer em adolescentes","volume":"87","author":"R A Fernandes","year":"2011","journal-title":"J Pediatr (Rio J)"},{"issue":"10","key":"ref37","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1007\/s00431-018-3206-y","article-title":"Unhealthy eating habits and participation in organized leisure-time activities in Czech adolescents","volume":"177","author":"J Vor\u00e1\u010dov\u00e1","year":"2018","journal-title":"Eur J Pediatr"},{"issue":"03","key":"ref38","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1152\/physrev.00038.2012","article-title":"Exercise, GLUT4, and skeletal muscle glucose uptake","volume":"93","author":"E A Richter","year":"2013","journal-title":"Physiol Rev"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1136\/bmj.323.7321.1123","article-title":"Statistics Notes Analysing controlled trials with baseline and follow up measurements","volume":"323","author":"A J Vickers","year":"2001","journal-title":"Bmj"},{"issue":"03","key":"ref40","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/sms.14261","article-title":"Association of physical activity with metabolic profile from adolescence to adulthood","volume":"33","author":"M Lehtovirta","year":"2023","journal-title":"Scand J Med Sci Sports"},{"issue":"07","key":"ref41","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1001\/jama.2012.156","article-title":"Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents","volume":"307","author":"U Ekelund","year":"2012","journal-title":"JAMA"},{"issue":"23","key":"ref42","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2015-095903","article-title":"Cardiorespiratory fitness cut points to avoid cardiovascular disease risk in children and adolescents; What level of fitness should raise a red flag? A systematic review and meta-analysis","volume":"50","author":"J R Ruiz","year":"2016","journal-title":"Br J Sports Med"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1038\/s41581-023-00781-2","article-title":"Sex differences in energy metabolism: natural selection, mechanisms and consequences","volume":"20","author":"F Mauvais-Jarvis","year":"2024","journal-title":"Nat Rev Nephrol"},{"issue":"02","key":"ref44","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jshs.2015.06.001","article-title":"Influence of different sports on fat mass and lean mass in growing girls","volume":"6","author":"E Ubago-Guisado","year":"2017","journal-title":"J Sport Health Sci"},{"issue":"13","key":"ref45","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1136\/bjsports-2015-094623","article-title":"Biological maturation of youth athletes: Assessment and implications","volume":"49","author":"R M Malina","year":"2015","journal-title":"Br J Sports Med"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"241","DOI":"10.3389\/fendo.2014.00241","article-title":"Sex-specific differences in lipid and glucose metabolism","volume":"5","author":"O Varlamov","year":"2014","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s13102-026-01544-9","article-title":"Effects of different exercise modalities on lipid profiles in overweight and obese children and adolescents: A systematic review and network meta-analysis of randomized controlled trials","volume":"18","author":"Q Liu","year":"2026","journal-title":"BMC Sports Sci Med Rehabil"},{"issue":"03","key":"ref48","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1139\/apnm-2013-0187","article-title":"Is high-intensity interval training a time-efficient exercise strategy to improve health and fitness?","volume":"39","author":"J B Gillen","year":"2014","journal-title":"App Physiol Nutr Metab"},{"issue":"08","key":"ref49","doi-asserted-by":"publisher","first-page":"e42","DOI":"10.1161\/01.atv.0000089628.63625.d4","article-title":"Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease","volume":"23","author":"P D Thompson","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"01","key":"ref50","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12944-022-01692-0","article-title":"The emerging role of skeletal muscle as a modulator of lipid profile the role of exercise and nutrition","volume":"21","author":"T Nomikos","year":"2022","journal-title":"Lipids Health Dis"},{"issue":"02","key":"ref51","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.atherosclerosis.2006.04.019","article-title":"Aerobic exercise and lipids and lipoproteins in children and adolescents: A meta-analysis of randomized controlled trials","volume":"191","author":"G A Kelley","year":"2007","journal-title":"Atherosclerosis"},{"issue":"07","key":"ref52","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1001\/jama.2012.156","article-title":"Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents","volume":"307","author":"U Ekelund","year":"2012","journal-title":"JAMA"},{"issue":"05","key":"ref53","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1038\/s41430-022-01242-y","article-title":"Intensity matters: Impact of physical activity energy expenditure at moderate and vigorous intensity on total and abdominal obesity in children","volume":"77","author":"L B Sardinha","year":"2023","journal-title":"Eur J Clin Nutr"},{"issue":"01","key":"ref54","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s13102-019-0150-8","article-title":"Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: The troms\u00f8 study, fit futures","volume":"11","author":"N A Aars","year":"2019","journal-title":"BMC Sports Sci Med Rehabil"},{"issue":"05","key":"ref55","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1007\/s00421-008-0743-5","article-title":"Vigorous physical activity and cytokines in adolescents","volume":"103","author":"D A Rubin","year":"2008","journal-title":"Eur J Appl Physiol"},{"issue":"03","key":"ref56","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1002\/cphy.c120033","article-title":"Muscle as a secretory organ","volume":"3","author":"B K Pedersen","year":"2013","journal-title":"Compr Physiol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/s41580-023-00606-x","article-title":"Exercise metabolism and adaptation in skeletal muscle","volume":"24","author":"JA B Smith","year":"2023","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"01","key":"ref58","doi-asserted-by":"publisher","first-page":"444","DOI":"10.3390\/ijerph20010444","article-title":"Impact of moderate-to-vigorous sports participation combined with resistance training on metabolic and cardiovascular outcomes among lean adolescents: ABCD Growth Study","volume":"20","author":"A E von Ah Morano","year":"2023","journal-title":"Int J Environ Res Public Health"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"103304","DOI":"10.1016\/j.eclinm.2025.103304","article-title":"World health Organization\u2019s guidance for tracking non-communicable diseases towards sustainable development goals 3.4: An initiative for facility-based monitoring","volume":"85","author":"A Quiambao","year":"2025","journal-title":"EClinicalMedicine"},{"issue":"32","key":"ref60","doi-asserted-by":"publisher","first-page":"2459","DOI":"10.1093\/eurheartj\/ehx144","article-title":"Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement fromthe European Atherosclerosis Society Consensus Panel","volume":"38","author":"B A Ference","year":"2017","journal-title":"Eur Heart J"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1016\/S0140-6736(21)00684-X","volume-title":"The Lancet women and cardiovascular disease Commission: Reducing the global burden by 2030","author":"B Vogel","year":"2021"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nrendo.2012.49","article-title":"Muscles, exercise and obesity: Skeletal muscle as a secretory organ","volume":"8","author":"B K Pedersen","year":"2012","journal-title":"Nat Rev Endocrinol"},{"issue":"04","key":"ref63","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1038\/icb.2014.16","article-title":"From cytokine to myokine\u202f: The emerging role of interleukin-6 in metabolic regulation","volume":"92","author":"M Pal","year":"2014","journal-title":"Immunol Cell Biol"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/s41580-023-00606-x","article-title":"Exercise metabolism and adaptation in skeletal muscle","volume":"24","author":"JA B Smith","year":"2023","journal-title":"Nat Rev Mol Cell Biol"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1007\/s40618-025-02726-x","article-title":"Estrogen in skeletal muscle: Metabolism, mechanisms, and exercise-induced changes","volume":"49","author":"Y Feng","year":"2025","journal-title":"J Endocrinol Invest"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"109306","DOI":"10.1016\/j.steroids.2023.109306","article-title":"An overview on androgen-mediated actions in skeletal muscle and adipose tissue","volume":"199","author":"J Rizk","year":"2023","journal-title":"Steroids"},{"issue":"02","key":"ref67","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1123\/pes.2021-0229","article-title":"Metabolic flexibility during exercise in children with overweight\/obesity versus children who are lean","volume":"35","author":"B Dykstra","year":"2023","journal-title":"Pediatr Exerc Sci"}],"container-title":["International Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2882-1662.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:30:40Z","timestamp":1790638240000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2882-1662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,11]]},"references-count":67,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,9,25]]},"published-print":{"date-parts":[[2026,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2882-1662","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0172-4622","1439-3964"],"issn-type":[{"value":"0172-4622","type":"print"},{"value":"1439-3964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,11]]}}}