{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:56:15Z","timestamp":1781308575050,"version":"3.54.1"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Nantes Universit\u00e9","award":["Ann\u00e9e Recherche"],"award-info":[{"award-number":["Ann\u00e9e Recherche"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background Small bowel (SB) capsule endoscopy (SBCE) is a key tool for Crohn\u2019s disease (CD), but interpretation is time-consuming. Artificial intelligence (AI) could assist, yet automated SB segmentation, a prerequisite for analysis, may be challenging in patients with CD.<\/jats:p>\n                  <jats:p>Aims To evaluate an AI model detecting the pylorus and ileocolonic junction in CD SBCEs.<\/jats:p>\n                  <jats:p>Methods SBCE videos from 60 patients with CD were annotated by three readers. A ResNet-18 convolutional neural network classified frames into stomach, SB, or colon, with Viterbi-based anatomically constrained segmentation, using five-fold cross-validation. Accuracy was assessed by discrepancies relative to expert annotations. Univariate analysis explored associated factors. Expert review was conducted for poorly localized cases.<\/jats:p>\n                  <jats:p>Results The model was trained on 596,980 images, including 426,674 SB images. Median localization error was 2 frames (1 s) for the pylorus and 118.5 frames (~5 min) for the ileocolonic junction. In 26 videos (43.3%), the model localized both junctions with a temporal discrepancy &lt;1 min compared with experts. In 53.3% of cases, AI detection of the ileocolonic junction preceded expert annotation by a median of 46 min, potentially leading to missed terminal ileal lesions. No factors were significantly associated with localization accuracy. Expert review highlighted inadequate cleanliness, capsule stagnation, and back-and-forth movements as main contributors to poor AI performance.<\/jats:p>\n                  <jats:p>Conclusions Our model successfully localizes both SB junctions in nearly half of SBCE videos from patients with CD. It consistently identifies the pylorus but shows modest performance at the ileocolonic junction. Capsule dynamics and bowel cleanliness remain major challenges for automated SB segmentation.<\/jats:p>","DOI":"10.1055\/a-2884-1351","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T23:08:20Z","timestamp":1779836900000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Artificial Intelligence-Based Localization of Small Bowel Anatomic Transition Zones in Crohn\u2019s Disease Using Capsule Endoscopy"],"prefix":"10.1055","volume":"14","author":[{"given":"Rapha\u00eblle","family":"Rouveyre","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, Pays de la Loire, France","place":["Nantes"],"department":["Institut des Maladies de l\u2019Appareil Digestif (IMAD), H\u00e9pato-Gastro-Ent\u00e9rologie et Assistance Nutritionnelle, Inserm CIC 1413"]},{"name":"Nantes Universit\u00e9, F-44000, Pays de la Loire, France","place":["Nantes"],"department":["Ecole Centrale Nantes, CNRS, LS2N, UMR 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