{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T22:49:26Z","timestamp":1782341366153,"version":"3.54.5"},"reference-count":69,"publisher":"Georg Thieme Verlag KG","funder":[{"name":"Bayerisches Zenturm f\u00fcr Krebsforschung","award":["Studiengruppenf\u00f6rderung P\u00e4diatrische Hirntumore"],"award-info":[{"award-number":["Studiengruppenf\u00f6rderung P\u00e4diatrische Hirntumore"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Padiatr"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>With the advent of multi-omic molecular profiling techniques, central nervous\n                    system tumor types previously not recognized by conventional neuropathological\n                    assessment have emerged, particularly among tumors formerly termed as \u201cCNS-\n                    primitive neuroectodermal tumors.\u201d Given the diverse histopathological,\n                    molecular, radiological, and clinical characteristics of these tumors,\n                    diagnostic approaches and treatment strategies need to be adapted to our\n                    increasing knowledge. The small number of patients per year for individual tumor\n                    types precludes large cohort studies and mandates international cooperation and\n                    harmonization. To this end, the SIOPE Brain Tumor Group together with the\n                    European Reference Network for Pediatric Cancers has published the European\n                    Standards of Clinical Practice guidelines for rare embryonal and sarcomatous\n                    tumors.<\/jats:p>","DOI":"10.1055\/a-2889-3506","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T22:33:00Z","timestamp":1782340380000},"source":"Crossref","is-referenced-by-count":0,"title":["Guidance for the Diagnosis and Treatment of Rare Embryonal and\n                    Sarcomatous Brain Tumors\u2014a Report from the Central Nervous System-International\n                    Registry for Rare Embryonal and Sarcomatous Tumors German Society of Pediatric\n                    Oncology and Hematology Study 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U.","family":"Schuhmann","sequence":"additional","affiliation":[{"name":"University of T\u00fcbingen, Germany","place":["T\u00fcbingen"],"department":["Division of Pediatric Neurosurgery, Department of\n                    Neurosurgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Schwarz","sequence":"additional","affiliation":[{"name":"University Medical Center\n                    Hamburg-Eppendorf, HH, Germany","place":["Hamburg"],"department":["Department of Radiotherapy and Radiooncology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Tietze","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology, Germany","place":["Berlin"],"department":["Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin\n                    and Humboldt-Universit\u00e4t zu Berlin"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Wagner","sequence":"additional","affiliation":[{"name":"University Hospital Augsburg, BY, Germany","place":["Augsburg"],"department":["Department of Neuroradiology and HIT reference center"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beate","family":"Timmermann","sequence":"additional","affiliation":[{"name":"University Essen, Germany","place":["Essen"],"department":["Westgerman Protontherapycenter Essen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"von Zezschwitz","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie\n                    Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin, Germany","place":["Berlin"],"department":["Department of Paediatric Hematology and 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