{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:43:43Z","timestamp":1782776623929,"version":"3.54.5"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To assess the impact of serial versus once-only transvaginal ultrasound (TVU) cervical length (CL) screening in twin pregnancies.<\/jats:p>\n                  <jats:p>Multicenter retrospective cohort study including twin pregnancies who underwent TVU CL screening from 160\/7 to 236\/7 weeks of gestation between 2017 and 2022. Twin pregnancies resulting from multifetal pregnancy reduction after 14 weeks of gestation, monochorionic monoamniotic twins, and those undergoing a history-indicated cerclage were excluded. Cases were stratified into two groups based on number of TVU CL assessments: twins who had more than one CL assessment from 160\/7 to 236\/7 weeks' gestation (i.e., serial CL group) versus twins who had only one CL assessment at the time of their detailed fetal anatomy ultrasound from 180\/7 to 216\/7 weeks' gestation (i.e., once-only CL group). Sensitivity, specificity, positive predictive value, and negative predictive value of CL screening for predicting preterm birth (PTB) at various gestational age cutoffs (&lt;34, &lt;32, and &lt;28 weeks of gestation) were calculated using thresholds of both \u226425 and \u226430\u2009mm and compared between the two groups. Statistical significance was set at p\u2009&lt;\u20090.05.<\/jats:p>\n                  <jats:p>Of the 1,917 patients included, 962 (50.2%) were in the serial CL group and 955 (49.8%) were in the once-only CL group. The incidence of a short CL \u2264 25\u2009mm was significantly higher in the serial CL group compared with the once-only CL group (12.6 vs. 0.9%, p &lt;0.001). The sensitivity of CL screening for predicting PTB, when using a threshold of \u226425\u2009mm, was higher in the serial CL group compared with the once-only CL group for each PTB cut-off (&lt;34 weeks: 27.9 vs. 4.2%; &lt;32 weeks: 40.7 vs. 7.4%; &lt;28 weeks: 47.2 vs. 11.8%, respectively).<\/jats:p>\n                  <jats:p>Serial TVU CL screening from 160\/7 to 236\/7 weeks of gestation should be considered in twin pregnancies.<\/jats:p>","DOI":"10.1055\/a-2889-9442","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T22:56:53Z","timestamp":1781045813000},"source":"Crossref","is-referenced-by-count":0,"title":["Serial versus Once-Only Cervical Length Screening in Twin Pregnancies"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1966-9578","authenticated-orcid":false,"given":"Moti","family":"Gulersen","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College of Thomas Jefferson University, Pennsylvania, United States","place":["Philadelphia"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]},{"name":"Feinstein Institutes for Medical Research, New York, United States","place":["Manhasset"],"department":["Northwell Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank I.","family":"Jackson","sequence":"additional","affiliation":[{"name":"South Shore University Hospital, New York, United States","place":["Bay Shore"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5534-6928","authenticated-orcid":false,"given":"Matthew J.","family":"Blitz","sequence":"additional","affiliation":[{"name":"Feinstein Institutes for Medical Research, New York, United States","place":["Manhasset"],"department":["Northwell Health"]},{"name":"South Shore University Hospital, New York, United States","place":["Bay Shore"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Insaf","family":"Kouba","sequence":"additional","affiliation":[{"name":"South Shore University Hospital, New York, United States","place":["Bay Shore"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burton","family":"Rochelson","sequence":"additional","affiliation":[{"name":"North Shore University Hospital, New York, United States","place":["Manhasset"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelby","family":"Keyser","sequence":"additional","affiliation":[{"name":"Axia Women's Health Management, Pennsylvania, United States","place":["Wynnewood"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Nicholas","sequence":"additional","affiliation":[{"name":"Axia Women's Health Management, Pennsylvania, United States","place":["Wynnewood"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8612-1825","authenticated-orcid":false,"given":"Mymy","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College of Thomas Jefferson University, Pennsylvania, United States","place":["Philadelphia"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashini","family":"Panchal","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College of Thomas Jefferson University, Pennsylvania, United States","place":["Philadelphia"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Bodycot","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College of Thomas Jefferson University, Pennsylvania, United States","place":["Philadelphia"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Berghella","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College of Thomas Jefferson University, Pennsylvania, United States","place":["Philadelphia"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Roman","sequence":"additional","affiliation":[{"name":"Sidney Kimmel Medical College of Thomas Jefferson University, Pennsylvania, United States","place":["Philadelphia"],"department":["Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"issue":"80","key":"ref1","first-page":"1","article-title":"Three decades of twin births in the United States, 1980-2009","author":"J A Martin","year":"2012","journal-title":"NCHS Data Brief"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"e145","DOI":"10.1097\/AOG.0000000000004397","article-title":"Multifetal gestations: twin, triplet, and higher-order multifetal pregnancies: ACOG practice bulletin, number 231","volume":"137","year":"2021","journal-title":"Obstet 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for the reduction of extreme preterm birth in twin pregnancies with a short cervix: a systematic review and meta-analysis","volume":"7","author":"L van Gils","year":"2025","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"01","key":"ref25","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1055\/s-0039-1694006","article-title":"Serial cervical length evaluation in low-risk women with shortened cervical lengths in the midtrimester: how many will dilate prior to 24 weeks?","volume":"37","author":"K B Zafman","year":"2020","journal-title":"Am J Perinatol"},{"issue":"02","key":"ref26","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/uog.29166","article-title":"ISUOG practice guidelines (updated): role of ultrasound in twin pregnancy","volume":"65","author":"A Khalil","year":"2025","journal-title":"Ultrasound Obstet Gynecol"}],"container-title":["American Journal of 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