{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:34:58Z","timestamp":1786120498742,"version":"build-2736575974"},"reference-count":56,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die bronchoalveol\u00e4re Lavage (BAL) ist ein minimalinvasives Verfahren, das h\u00e4ufig zur Abkl\u00e4rung pulmonaler Erkrankungen eingesetzt wird. Die Hauptindikationen umfassen die Entz\u00fcndungs- und Infektionsdiagnostik sowie die Abkl\u00e4rung interstitieller Lungenerkrankungen. Dar\u00fcber hinaus kommt der Methode eine Bedeutung in der Tumordiagnostik, bei der Erkennung von Absto\u00dfungsreaktionen nach Lungentransplantation sowie in der Diagnostik von Berufserkrankungen (z.B. Berylliose, Asbestose) zu.Wenngleich die BAL allein meist keine definitive Diagnose erm\u00f6glicht, liefert die Analyse der BAL-Fl\u00fcssigkeit wichtige Befunde, die im klinischen Kontext unverzichtbar sind. Voraussetzung f\u00fcr eine erfolgreiche Befunderhebung und Interpretation sind eine sorgf\u00e4ltige Materialentnahme und deren rasche Verarbeitung. Die Aufarbeitung ist technisch einfach und die Routinef\u00e4rbung (Giemsa) wenig aufwendig. Die BAL ist breit verf\u00fcgbar, kosteng\u00fcnstig und im Rahmen der Diagnostik pulmonaler Erkrankungen ein unverzichtbares Werkzeug.<\/jats:p>","DOI":"10.1055\/a-2890-6912","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T22:57:12Z","timestamp":1786057032000},"source":"Crossref","is-referenced-by-count":0,"title":["Bronchoalveol\u00e4re Lavage (BAL) \u2013 ein aktueller \u00dcberblick"],"prefix":"10.1055","author":[{"given":"Niels","family":"Schr\u00f6der","sequence":"additional","affiliation":[{"name":"Ruhrlandklinik, Universit\u00e4tsmedizin Essen, Deutschland","place":["Essen"],"department":["Zentrum f\u00fcr interstitielle und seltene Lungenerkrankungen, Klinik f\u00fcr Pneumologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Breyer","sequence":"additional","affiliation":[{"name":"Asklepios Kliniken GmbH & Co KGaA, Deutschland","place":["Hamburg"],"department":["Pneumologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Breyer","sequence":"additional","affiliation":[{"name":"Krankenhaus St. Elisabeth und St. Barbara Halle\/Saale, Medizinische Klinik 3, Deutschland","place":["Halle\/Saale"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Bonella","sequence":"additional","affiliation":[{"name":"Ruhrlandklinik, Universit\u00e4tsmedizin Essen, Deutschland","place":["Essen"],"department":["Zentrum f\u00fcr interstitielle und seltene Lungenerkrankungen, Klinik f\u00fcr Pneumologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Heine","sequence":"additional","affiliation":[{"name":"Krankenhaus St. Elisabeth und St. Barbara Halle\/Saale, Medizinische Klinik 3, Deutschland","place":["Halle\/Saale"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"4991","DOI":"10.21037\/jtd-20-651","article-title":"Bronchoalveolar lavage as a diagnostic procedure: a review of known cellular and molecular findings in various lung diseases","volume":"12","author":"KR Davidson","year":"2020","journal-title":"J Thorac Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1002\/dc.24574","article-title":"Role of bronchoalveolar lavage in diagnosing pulmonary infections and malignancies: Experience from a tertiary care center","volume":"48","author":"A Zaidi","year":"2020","journal-title":"Diagn Cytopathol"},{"key":"ref3","article-title":"Galactomannan detection in broncho-alveolar lavage fluid for invasive aspergillosis in immunocompromised patients","volume":"5","author":"K de Heer","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"ref4","volume-title":"Bronchoalveol\u00e4re Lavage","author":"J M\u00fcller-Quernheim","year":"1998"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.3390\/diagnostics12122949","article-title":"Bronchoalveolar Lavage Fluid-Isolated Biomarkers for the Diagnostic and Prognostic Assessment of Lung Cancer","volume":"12","author":"A Kalkanis","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1055\/s-2007-991527","article-title":"Bronchoalveolar lavage as a diagnostic tool","volume":"28","author":"KC Meyer","year":"2007","journal-title":"Semin Respir Crit Care Med"},{"key":"ref7","first-page":"230","article-title":"Bronchoalveolar lavage fluid assessment facilitates precision medicine for lung cancer","volume":"21","author":"H Zhang","year":"2023","journal-title":"Cancer Biol Med"},{"key":"ref8","first-page":"e2","article-title":"Diagnosis and assessment of the occupational silica dust lung disease (silicosis) - 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