{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:57:50Z","timestamp":1785455870416,"version":"3.56.0"},"reference-count":103,"publisher":"Georg Thieme Verlag KG","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Planta Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Age-related diseases like dementia are increasing globally, with limited treatments. Extracts of Ginkgo biloba are often used alongside synthetic drugs. The aim of this article was to identify clinical guidelines from countries around the world to assess recommendations on the use of Ginkgo biloba in dementia, mild cognitive impairment, and prevention. PubMed was systematically searched for guidelines on dementia and mild cognitive impairment on the 25th of April 2023. A search update was conducted on the 3rd of March 2026. Additional guidelines were identified via citation searching and organisations. Seventy-seven guideline documents were included: 47 on dementia (subtype not further defined), 25 on Alzheimer\u02bcs disease, 19 on vascular dementia, 18 on mild cognitive impairment, and seven on prevention, with some guidelines including multiple mentions. The guidelines come from four continents and 28 countries, plus seven international guidelines. Regarding Ginkgo biloba, 52 give positive, 18 negative, and 26 neutral recommendations (double mentions possible); 27 do not mention it. Ginkgo biloba is referred to in guidelines worldwide, usually without reference to specific preparations. Preparation standardisation would be beneficial.<\/jats:p>","DOI":"10.1055\/a-2895-5345","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:00:57Z","timestamp":1785452457000},"source":"Crossref","is-referenced-by-count":0,"title":["Ginkgo biloba Leaf Extracts in Global Dementia and Mild Cognitive Impairment Guidelines. A Review"],"prefix":"10.1055","author":[{"given":"Katrin","family":"Pfuhlmann","sequence":"additional","affiliation":[{"name":"Department of Integrative Medicine, Medical Faculty, University of Duisburg-Essen, Duisburg-Essen, North Rhine-Westphalia, Germany"},{"name":"Department of Internal and Integrative Medicine, Sozialstiftung Bamberg, Bavaria, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Katharina","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Integrative Medicine, Medical Faculty, University of Duisburg-Essen, Duisburg-Essen, North Rhine-Westphalia, Germany"},{"name":"Department of Internal and Integrative Medicine, Sozialstiftung Bamberg, Bavaria, Germany"},{"name":"Charit\u00e9 Competence Center for Traditional and Integrative Medicine (CCCTIM), Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7900-181X","authenticated-orcid":false,"given":"Jost","family":"Langhorst","sequence":"additional","affiliation":[{"name":"Department of Integrative Medicine, Medical Faculty, University of Duisburg-Essen, Duisburg-Essen, North Rhine-Westphalia, Germany"},{"name":"Department of Internal and Integrative Medicine, Sozialstiftung Bamberg, Bavaria, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"ref1","volume-title":"Dementia","author":"World Health Organisation"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/alz.12328","article-title":"Alzheimer\u02bcs Association Report; 2021 Alzheimer\u02bcs disease facts and figures","volume":"17","author":"The Alzheimer\u02bcs Association","year":"2021","journal-title":"Alzheimers Dement"},{"key":"ref3","first-page":"470","article-title":"Dementia in Germany: Epidemiology and prevention potential","volume":"120","author":"I Blotenberg","year":"2023","journal-title":"Dtsch Arztebl International"},{"key":"ref4","first-page":"373","article-title":"Decline in incidence and prevalence of dementia: An analysis of outpatient claims data","volume":"122","author":"B Michalowsky","year":"2025","journal-title":"Dtsch Arztebl Int"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e443-e460","DOI":"10.1016\/S2468-2667(24)00120-8","article-title":"Changes in prevalence and incidence of dementia and risk factors for dementia: An analysis from cohort studies","volume":"9","author":"N Mukadam","year":"2024","journal-title":"Lancet Public Health"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/alz.12188","article-title":"Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations","volume":"17","author":"S AM Sikkes","year":"2021","journal-title":"Alzheimers Dement"},{"key":"ref7","first-page":"157","article-title":"[Pharmacological treatment of dementia]","volume":"147","author":"M Kirsch","year":"2022","journal-title":"Dtsch Med Wochenschr"},{"key":"ref8","volume-title":"Medikamente bei Alzheimer","author":"A Pfitzer-Bilsing"},{"key":"ref9","volume-title":"S3-Leitlinie Demenzen, Version 6.1, 24. 02. 2026","author":"DGN e.V. & DGPPN e. V. (Hrsg.)"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"779","DOI":"10.3233\/JAD-180766","article-title":"Treatment combinations for alzheimer\u02bcs disease: Current and future pharmacotherapy options","volume":"67","author":"J L Cummings","year":"2019","journal-title":"J Alzheimers Dis"},{"key":"ref11","volume-title":"Ginkgo folium \u2013 herbal medicinal product","author":"European Medicines Agency Committee on Herbal Medicinal Products"},{"issue":"2009","key":"ref12","first-page":"CD003120","article-title":"Ginkgo biloba for cognitive impairment and dementia","author":"J Birks","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"156565","DOI":"10.1016\/j.phymed.2025.156565","article-title":"Ginkgo biloba leaf extract EGb 761\u00ae for the treatment of various diseases: Overview of systematic reviews","volume":"141","author":"K Pfuhlmann","year":"2025","journal-title":"Phytomedicine"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/15622975.2024.2446830","article-title":"Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia \u2013 a meta-analysis of patient subgroups in randomised controlled trials","volume":"26","author":"M Riepe","year":"2025","journal-title":"World J Biol Psychiatry"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1017\/S1041610217001892","article-title":"Treatment effects of Ginkgo biloba extract EGb 761\u00ae on the spectrum of behavioral and psychological symptoms of dementia: Meta-analysis of randomized controlled trials","volume":"30","author":"E Savaskan","year":"2018","journal-title":"Int Psychogeriatr"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1007\/s40120-023-00504-6","article-title":"A systematic review of clinical practice guidelines for alzheimer\u02bcs disease and strategies for future advancements","volume":"12","author":"A A Tahami Monfared","year":"2023","journal-title":"Neurol Ther"},{"key":"ref17","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions. Version 6.5 (updated August 2024)","author":"J PT Higgins"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s41073-019-0064-8","article-title":"SANRA\u2013a scale for the quality assessment of narrative review articles","volume":"4","author":"C Baethge","year":"2019","journal-title":"Res Integr Peer Rev"},{"key":"ref19","volume-title":"THAI dementia clinical practice guideline 2020","author":"A Rojana-Udomsart"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3109\/15622975.2010.538083","article-title":"World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of Alzheimer\u02bcs disease and other dementias","volume":"12","author":"R Ihl","year":"2011","journal-title":"World J Biol Psychiatry"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/cns.13095","article-title":"Treatment of dementia and mild cognitive impairment with or without cerebrovascular disease: Expert consensus on the use of Ginkgo biloba extract, EGb 761\u00ae","volume":"25","author":"N Kandiah","year":"2019","journal-title":"CNS Neurosci Ther"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/cns.13536","article-title":"Strategies for the use of Ginkgo biloba extract, EGb 761\u00ae, in the treatment and management of mild cognitive impairment in Asia: Expert consensus","volume":"27","author":"N Kandiah","year":"2021","journal-title":"CNS Neurosci Ther"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2174\/1573401317666210910120735","article-title":"Ginkgo Biloba: A famous living fossil tree and an ancient herbal Traditional Chinese Medicine","volume":"18","author":"M H Shahrajabian","year":"2022","journal-title":"Current Nutrition & Food Science"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1007746","DOI":"10.3389\/fphar.2022.1007746","article-title":"Ginkgo biloba leaf extract EGb 761\u00ae as a paragon of the product by process concept","volume":"13","author":"Z Kulic","year":"2022","journal-title":"Front Pharmacol"},{"key":"ref25","volume-title":"Trockenextrakt (35 \u2013 67: 1) aus Ginkgo-biloba-Bl\u00e4ttern, extrahiert mit Aceton-Wasser. Monographie BGA\/BfArM (Kommission E). Bundesanzeiger, 19. 7. 1994, Heftnr. 113., ATC-Code: N07XF","author":"Bundesgesundheitsamt (BGA)\/Bundesinstitut f\u00fcr Arzneimittel und Medizinprodukte (BfArM) (Kommission E)"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10590501.2016.1278298","article-title":"Review of Ginkgo biloba-induced toxicity, from experimental studies to human case reports","volume":"35","author":"N Mei","year":"2017","journal-title":"J Environ Sci Health C"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1211\/0022357021778970","article-title":"Pharmaceutical quality of different Ginkgo biloba brands","volume":"54","author":"S Kressmann","year":"2002","journal-title":"J Pharm Pharmacol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1002\/rcm.2646","article-title":"Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography\/mass spectrometry","volume":"20","author":"S Ding","year":"2006","journal-title":"Rapid Commun Mass Spectrom"},{"key":"ref29","first-page":"335","article-title":"Comparative analysis of pharmaceuticals and dietary supplements containing extracts from the leaves of Ginkgo biloba L","volume":"67","author":"A Gawron-Gzella","year":"2010","journal-title":"Acta Pol Pharm"},{"key":"ref30","first-page":"54","article-title":"Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba","volume":"2010","author":"H P Fransen","year":"2010","journal-title":"Food Nutr Res"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"9226","DOI":"10.1039\/D2FO01827F","article-title":"A critical review of ginkgolic acids in Ginkgo biloba leaf extract (EGb): Toxicity and technologies to remove ginkgolic acids and their promising bioactivities","volume":"13","author":"I D Boateng","year":"2022","journal-title":"Food Funct"},{"key":"ref32","volume-title":"IARC monographs on the evaluation of carcinogenic risks to humans. International Agency for Research on Cancer (IARC) working group on the evaluation of carcinogenic risks to humans. Some drugs and herbal products","author":"International Agency for Research on Cancer and World Health Organization"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1067\/mjd.2001.118545","article-title":"Diffuse morbilliform eruption after consumption of ginkgo biloba supplement","volume":"46","author":"A E Chiu","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"ref34","volume-title":"Review of available information pertaining to the safety of Ginkgo biloba extract for use in conventional foods","author":"Public Health Service Food and Drug Administration"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"M J Page","year":"2021","journal-title":"BMJ"},{"key":"ref37","volume-title":"Konsensus-Statement 2025 Demenzerkrankungen. \u00d6sterreichische Gesellschaft f\u00fcr Neuropsychopharmakologie und Biologische Psychiatrie (\u00d6GPB). JATROS Neurologie & Psychiatrie","author":"D Rujescu"},{"key":"ref38","first-page":"67","article-title":"[Consensus statement \u201cDementia 2010\u201d of the Austrian Alzheimer Society]","volume":"24","author":"R Schmidt","year":"2010","journal-title":"Neuropsychiatr"},{"key":"ref39","volume-title":"Dementia, disability and frailty in later life \u2013 midlife approaches to delay or prevent onset. NICE guideline","author":"National Institute for Health and Care Excellence"},{"key":"ref40","volume-title":"National Institute for Health and Care Excellence: Guidelines","author":"National Collaborating Centre for Mental Health","year":"2007"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1177\/0269881116680924","article-title":"Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology","volume":"31","author":"J T O\u02bcBrien","year":"2017","journal-title":"J Psychopharmacol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1177\/0269881110387547","article-title":"Clinical practice with anti-dementia drugs: A revised (second) consensus statement from the British Association for Psychopharmacology","volume":"25","author":"J T O\u02bcBrien","year":"2011","journal-title":"J Psychopharmacol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1093\/ageing\/afaa228","article-title":"Mild cognitive impairment: The Manchester consensus","volume":"50","author":"R A Dunne","year":"2021","journal-title":"Age Ageing"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"afae147","DOI":"10.1093\/ageing\/afae147","article-title":"Guideline summary: Assessment, diagnosis, care and support for people with dementia and their carers [Scottish Intercollegiate Guidelines Network SIGN Guideline 168]","volume":"53","author":"J K Burton","year":"2024","journal-title":"Age Ageing"},{"key":"ref45","first-page":"228","article-title":"[Pharmacological treatment of dementia: When, how and for how long. Recommendations of the Working Group on Dementia of the Catalan Society of Geriatrics and Gerontology]","volume":"47","author":"D Rodr\u00edguez","year":"2012","journal-title":"Rev Esp Geriatr Gerontol"},{"key":"ref46","volume-title":"Doporu\u010den\u00e9 diagnostick\u00e9 a terapeutick\u00e9 postupy pro v\u0161eobecn\u00e9 praktick\u00e9 l\u00e9ka\u0159e DEMENCE (Recommended diagnostic and therapeutic procedures for general practitioners DEMENTIA). Centrum doporu\u010den\u00fdch postup\u016f pro praktick\u00e9 l\u00e9ka\u0159e","author":"A Mat\u011bjkov\u00e1"},{"key":"ref47","volume-title":"Czech and Slovak neurology and neurosurgery. Recommendations for the diagnosis and management of Alzheimer\u02bcs disease and other disorders associated with dementia","author":"K Sheardov\u00e1"},{"key":"ref48","volume-title":"Doporu\u010den\u00e9 diagnostick\u00e9 a terapeutick\u00e9 postupy pro v\u0161eobecn\u00e9 praktick\u00e9 l\u00e9ka\u0159e. Demence. Centrum doporu\u010den\u00fdch postup\u016f pro praktick\u00e9 l\u00e9ka\u0159e Spole\u010dnost v\u0161eobecn\u00e9ho l\u00e9ka\u0159stv\u00ed","author":"H Mat\u011bjovsk\u00e1 Kube\u0161ov\u00e1"},{"key":"ref49","volume-title":"Novinky v L\u00e9\u010db\u011b Alzheimerovy Nemoci (New Developments in the Treatment of Alzheimer\u02bcs Disease). S\u00f9kl \u2013 State Institute of Drug Control","author":"Z Dole\u017eel"},{"key":"ref50","volume-title":"Psychiatrick\u00e1 spole\u010dnost \u010cLS JEP, \u010cesk\u00e1 psychiatrick\u00e1 spole\u010dnost o. s. Psychiatrie: Doporu\u010den\u00e9 postupy psychiatrick\u00e9 p\u00e9\u010de IV (Psychiatry: Recommended practices in psychiatric care IV)","author":"J Raboch"},{"key":"ref52","volume-title":"Nationale kliniske anbefalinger for mennesker med demens med adf\u00e6rdsm\u00e6ssige og psykiske symptomer (National clinical recommendations for people with dementia with behavioral and psychological symptoms). Sundhedsstyrelsen","author":"A B Kristensen"},{"key":"ref53","first-page":"868","article-title":"[Consensus statement on severe dementia]","volume":"161","author":"B Vellas","year":"2005","journal-title":"Rev Neurol (Paris)"},{"key":"ref54","volume-title":"Maladie d\u02bcAlzheimer et maladies apparent\u00e9es: Diagnostic et prise en charge (Alzheimer\u02bcs disease and related disorders: Diagnosis and management)","author":"Haute Autorit\u00e9 de Sant\u00e9"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.neurol.2012.02.009","article-title":"Recommendations for the detection and therapeutic management of cognitive impairment in multiple sclerosis","volume":"168","author":"C Bensa","year":"2012","journal-title":"Rev Neurol (Paris)"},{"key":"ref56","volume-title":"Eg\u00e9szs\u00e9g\u00fcgyi szakmai ir\u00e1nyelv: A demencia k\u00f3rism\u00e9z\u00e9se, kezel\u00e9se \u00e9s gondoz\u00e1sa (Health professional guideline: Dementia diagnosis, treatment and care). EG\u00c9SZS\u00c9G\u00dcGYI SZAKMAI KOLL\u00c9GIUM","author":"K Borb\u00e9ly"},{"key":"ref57","first-page":"202","article-title":"Aj\u00e1nl\u00e1s demenci\u00e1k kivizsg\u00e1l\u00e1s\u00e1ra \u00e9s gy\u00f3gykezel\u00e9s\u00e9re","volume":"17","author":"P Tariska","year":"2002","journal-title":"Psych Hung"},{"key":"ref58","volume-title":"Dementia Diagnosis & Management in General Practice Quick Reference Guide. Quality and Safety in Practice Committee","author":"T Foley","year":"2019"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00002512-200522001-00002","article-title":"Guidelines for the treatment of alzheimer\u02bcs disease from the Italian association of psychogeriatrics","volume":"22","author":"C Caltagirone","year":"2005","journal-title":"Drugs & Aging"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"afae250","DOI":"10.1093\/ageing\/afae250","article-title":"The Italian guideline on diagnosis and treatment of dementia and mild cognitive impairment","volume":"53","author":"E Fabrizi","year":"2024","journal-title":"Age Ageing"},{"key":"ref61","volume-title":"Demencia pri Alzheimerovej chorobe. Ministerstvo zdravotn\u00edctva Slovenskej republiky","author":"M Kr\u00e1lov\u00e1"},{"key":"ref62","volume-title":"Gu\u00edas diagn\u00f3sticas y terap\u00e9uticas de la Sociedad Espa\u00f1ola de Neurolog\u00eda 2018. 5. Gu\u00eda oficial de pr\u00e1ctica cl\u00ednica en demencias","author":"Sociedad Espa\u00f1ola de Neurolog\u00eda"},{"key":"ref63","volume-title":"Gu\u00eda de Pr\u00e1ctica Cl\u00ednica sobre la atenci\u00f3n integral a las personas con enfermedad de Alzheimer y otras demencias. Plan de Calidad para el Sistema Nacional de Salud del Ministerio de Sanidad, Pol\u00edtica Social e Igualdad. Ag\u00e8ncia d\u02bcInformaci\u00f3, Avaluaci\u00f3 i Qualitat en Salut de Catalu\u00f1a; 2010. Gu\u00edas de Pr\u00e1ctica Cl\u00ednica en el SNS: AIAQS N\u00fam. 2009\/07","author":"Grupo de trabajo de la Gu\u00eda de Pr\u00e1ctica Cl\u00ednica sobre la atenci\u00f3n integral a las personas con enfermedad de Alzheimer y otras demencias"},{"key":"ref64","volume-title":"Practical Guide for Alzheimer\u02bcs Professionals","author":"Fundacion Reina Sofia"},{"key":"ref65","volume-title":"Deteriorio cognitivo leve en el adulto mayor. Documento de consenso. Sociedad Espa\u00f1ola de Geriatr\u00eda y Gerontolog\u00eda","author":"E Arriola Manchola"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0212-6567(18)30365-2","article-title":"Actividades preventivas en los mayores. Actualizaci\u00f3n PAPPS 2018","volume":"50","author":"M DC de Hoyos Alonso","year":"2018","journal-title":"Aten Primaria"},{"key":"ref67","volume-title":"Guideline Demenz. mednetbern AG","author":"A Giani"},{"key":"ref68","volume-title":"Guideline Demenz. Medix Guidelines","author":"I Bopp-Kistler"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1024\/1661-8157\/a001547","article-title":"Empfehlungen zur Diagnostik und Therapie der behavioralen und psychologischen Symptome der Demenz (BPSD)","volume":"103","author":"E Savaskan","year":"2014","journal-title":"Praxis"},{"key":"ref70","first-page":"187","article-title":"[The Swiss memory clinics recommendations for the treatment of dementia]","volume":"113","author":"S Kl\u00f6ppel","year":"2024","journal-title":"Praxis (Bern 1994)"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/agm2.12073","article-title":"Clinical practice guideline for cognitive impairment of cerebral small vessel disease","volume":"2","author":"D Peng","year":"2019","journal-title":"Aging Med"},{"key":"ref72","volume-title":"Dementia in India 2020","author":"Alzheimer\u02bcs and Related Disorders Society of India (ARDSI)"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"S312-s328","DOI":"10.4103\/0019-5545.224472","article-title":"Clinical practice guidelines for management of dementia","volume":"60","author":"K S Shaji","year":"2018","journal-title":"Indian J Psychiatry"},{"key":"ref74","volume-title":"Paduan praktik klinik demensia (Dementia clinic practice guidelines)"},{"key":"ref75","volume-title":"Clinical practice guideline for dementia 2017","author":"Japanese Society of Neurology"},{"key":"ref76","volume-title":"Clinical Practice Guidelines. Management of Dementia. Third edition. Ministry of Health Malaysia. Malaysian Health Technology Assessment Section. Putrajaya, Malaysia","author":"C Y Fai"},{"key":"ref77","volume-title":"Clinical practice guidelines for management of dementia. Academy of Medicine of Malaysia","author":"S Yusoff"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"6","DOI":"10.17116\/jnevro20211211036","article-title":"Clinical guidelines for cognitive disorders in elderly and older patients","volume":"121","author":"A Bogolepova","year":"2021","journal-title":"Zh Nevrol Psikhiatr im SS Korsakova"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"7","DOI":"10.17116\/jnevro2025125337","article-title":"[Clinical guidelines \u00abCognitive disorders in the elderly and senile persons\u00bb]","volume":"125","author":"O N Tkacheva","year":"2025","journal-title":"Zh Nevrol Psikhiatr Im S S Korsakova"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"293","DOI":"10.11622\/smedj.2013112","article-title":"Ministry of health clinical practice guidelines: dementia","volume":"54","author":"K Nagaendran","year":"2013","journal-title":"Singapore Med J"},{"key":"ref81","first-page":"292","article-title":"Taiwan Dementia Treatment Guideline","volume":"15","author":"L K Huang","year":"2021","journal-title":"International Journal of Gerontology"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"120","DOI":"10.5770\/cgj.15.49","article-title":"Recommendations of the 4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD4)","volume":"15","author":"S Gauthier","year":"2012","journal-title":"Can Geriatr J"},{"key":"ref84","first-page":"433","article-title":"Fourth canadian consensus conference on the diagnosis and treatment of dementia: Recommendations for family physicians","volume":"60","author":"A Moore","year":"2014","journal-title":"Can Fam Physician"},{"key":"ref85","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1002\/alz.12105","article-title":"Recommendations of the 5th Canadian Consensus Conference on the diagnosis and treatment of dementia","volume":"16","author":"Z Ismail","year":"2020","journal-title":"Alzheimers Dement"},{"key":"ref86","volume-title":"Gu\u00eda de Pr\u00e1ctica Cl\u00ednica, Diagn\u00f3stico y Tratamiento del Deterioro Cognoscitivo en el Adulto Mayor en el Primer Nivel de Atenci\u00f3n","author":"Secretaria de Salud M\u00e9xico"},{"key":"ref87","volume-title":"Gu\u00eda de Referencia R\u00e1pida. Diagn\u00f3stico y Tratamiento de la Demencia tipo Alzheimer (Quick Reference Guide. Diagnosis and Treatment of Alzheimer\u02bcs Dementia)","author":"Gobierno Federal Estados unidos mixicanos"},{"key":"ref88","volume-title":"Gu\u00eda de Referencia R\u00e1pida. Diagn\u00f3stico y Tratamiento de la Demencia Vascular (Quick Reference Guide. Diagnosis and Treatment of Vascular Dementia)","author":"Gobierno Federal Estados unidos mixicanos"},{"key":"ref89","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1046\/j.1365-2389.2003.51272.x","article-title":"Guidelines abstracted from the American Academy of Neurology\u02bcs Dementia Guidelines for Early Detection, Diagnosis, and Management of Dementia","volume":"51","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"ref90","doi-asserted-by":"crossref","first-page":"370","DOI":"10.7326\/0003-4819-148-5-200803040-00008","article-title":"Current pharmacologic treatment of dementia: A clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians","volume":"148","author":"A Qaseem","year":"2008","journal-title":"Ann Intern Med"},{"key":"ref91","first-page":"5","article-title":"American Psychiatric Association practice guideline for the treatment of patients with Alzheimer\u02bcs disease and other dementias. Second edition","volume":"164","author":"P V Rabins","year":"2007","journal-title":"Am J Psychiatry"},{"key":"ref92","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1212\/WNL.56.9.1154","article-title":"Practice parameter: management of dementia (an evidence-based review). 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Treatment","volume":"65","author":"J L Cummings","year":"2002","journal-title":"Am Fam Physician"},{"key":"ref96","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1212\/WNL.0000000000004826","article-title":"Practice guideline update summary: Mild cognitive impairment: Report of the guideline development, dissemination, and implementation subcommittee of the American academy of neurology","volume":"90","author":"R C Petersen","year":"2018","journal-title":"Neurology"},{"key":"ref97","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.mayocp.2013.04.024","article-title":"The national task group on intellectual disabilities and dementia practices consensus recommendations for the evaluation and management of dementia in adults with intellectual disabilities","volume":"88","author":"J A Moran","year":"2013","journal-title":"Mayo Clin Proc"},{"key":"ref98","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1212\/01.wnl.0000187889.17253.b1","article-title":"Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium","volume":"65","author":"I G McKeith","year":"2005","journal-title":"Neurology"},{"key":"ref99","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.apmr.2025.05.007","article-title":"What is Mild Cognitive Impairment (MCI)? 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Sydney","author":"Guideline Adaptation Committee"},{"key":"ref103","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1111\/ene.14412","article-title":"A European Academy of Neurology guideline on medical management issues in dementia","volume":"27","author":"K S Frederiksen","year":"2020","journal-title":"Eur J Neurol"},{"key":"ref104","volume-title":"Risk reduction of cognitive decline and dementia: WHO guidelines. 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