{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:31:32Z","timestamp":1793406692441,"version":"4.5.0"},"reference-count":64,"publisher":"Georg Thieme Verlag KG","issue":"12","funder":[{"name":"Ludeman Family Center for Women\u2019s Health Research at the University of Colorado","award":["Early-Career Faculty Research Development Award"],"award-info":[{"award-number":["Early-Career Faculty Research Development Award"]}],"id":[{"id":"https:\/\/ror.org\/031e8jz65","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Colorado Specialized Center of Research Excellence on Sex Differences","award":["U54 AG062319"],"award-info":[{"award-number":["U54 AG062319"]}]},{"name":"Colorado Nutrition Obesity Research Center","award":["P30 DK048520"],"award-info":[{"award-number":["P30 DK048520"]}]},{"name":"NIH\/NCATS Colorado CTSA","award":["UM1 TR004399, K12 TR004412"],"award-info":[{"award-number":["UM1 TR004399, K12 TR004412"]}],"id":[{"id":"https:\/\/ror.org\/03xsh7c04","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Amenorrhea in female athletes may be associated with cardiovascular disease risk factors. We aimed to implement a rigorous methodology to confirm menstrual status and examine differences in lipid and inflammatory markers between amenorrheic and eumenorrheic adolescent athletes. We included 13\u201318-year-old participants who were over 1-year post-menarchal and not using hormonal medications. Participants reporting\u22659 menstrual periods in the prior year underwent a prospective methodology to be classified as eumenorrheic. Those reporting no menstrual period for more than three consecutive months prior to enrollment were classified as amenorrheic. We compared lipid and inflammatory markers between eumenorrheic and amenorrheic groups. There were 32 participants included (n=12 eumenorrheic; n=10 amenorrheic; n=4 anovulatory; and n=6 oligomenorrheic), with 96.5% adherence to the menstrual tracking protocol. The amenorrheic group demonstrated higher high-density lipoprotein levels (60.8 vs. 52.7; p=0.04) and trended toward lower C-reactive protein levels (0.43 vs. 1.53; p=0.07) than the eumenorrheic group. Amenorrheic athletes did not demonstrate cardiovascular disease risk factors compared with eumenorrheic athletes, contrary to what has been observed in prior studies of adult athletes. We demonstrated feasibility and success in implementing a rigorous methodology to classify and confirm menstrual status in an adolescent athlete population that can be replicated in future studies.<\/jats:p>","DOI":"10.1055\/a-2896-9042","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:25:47Z","timestamp":1784939147000},"page":"945-955","source":"Crossref","is-referenced-by-count":0,"title":["Menstrual Profiles and Cardiovascular Markers Among a Cohort of Female Adolescent Athletes"],"prefix":"10.1055","volume":"47","author":[{"given":"Kaylee P.","family":"Blevins","sequence":"additional","affiliation":[{"name":"University of Colorado School of Medicine, Colorado, United States","place":["Aurora"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madison","family":"Brna","sequence":"additional","affiliation":[{"name":"University of North Carolina School of Medicine, North Carolina, United States","place":["Chapel 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