{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:00:54Z","timestamp":1785452454475,"version":"3.56.0"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Transition von Jugendlichen mit Besonderheiten der Geschlechtsentwicklung (DSD) in die Erwachsenenmedizin stellt aufgrund medizinischer, psychosozialer und ethischer Anforderungen einen komplexen Prozess dar. Viele DSD-Diagnosen sind selten und in der Erwachsenenmedizin wenig bekannt, was eine strukturierte Vorbereitung unerl\u00e4sslich macht.Der Artikel fasst die Anforderungen aus Leitlinien, dem Berliner Transitionsprogramm sowie klinischen Erfahrungsberichten zusammen. Anhand typischer Fallkonstellationen (z.\u202fB. Hypospadie, AGS, CAIS, Gonadendysgenesie) werden Herausforderungen, Therapieziele und notwendige Kompetenzen im Transitionsprozess dargestellt.Die Analyse zeigt, dass eine gelingende Transition von klaren Informationswegen, interdisziplin\u00e4rer Zusammenarbeit, medizinischer Kontinuit\u00e4t und der F\u00f6rderung patientenseitiger Autonomie abh\u00e4ngt. Zentral sind u.\u202fa. das Management hormoneller Fragestellungen, die Bewertung struktureller Genitalver\u00e4nderungen, die Tumorrisikobeurteilung sowie psychosoziale Unterst\u00fctzung. Barrieren bestehen h\u00e4ufig in mangelnder Akzeptanz der Diagnose, fehlenden Ressourcen und Wissensl\u00fccken in der Erwachsenenmedizin.Ein individualisierter Transitionsplan, erg\u00e4nzt durch Epikrisen, Bildgebung und strukturierte Patientenschulungen, verbessert die Versorgung und st\u00e4rkt Selbstbestimmung sowie Teilhabe der Betroffenen. Der Transitionsprozess bietet Chancen zur Reflexion fr\u00fcherer Behandlungsentscheidungen, zur St\u00e4rkung der Eltern und zur Weiterentwicklung des medizinischen Verst\u00e4ndnisses von Identit\u00e4t, Gender und Sexualit\u00e4t.<\/jats:p>","DOI":"10.1055\/a-2897-1582","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T22:46:56Z","timestamp":1782946016000},"page":"366-372","source":"Crossref","is-referenced-by-count":0,"title":["Die Transition bei Besonderheiten der Geschlechtsentwicklung (DSD): Vom Menschen zur Person"],"prefix":"10.1055","volume":"57","author":[{"given":"Anne-Nele","family":"Schr\u00f6der","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Schleswig-Holstein Campus L\u00fcbeck, Germany","place":["L\u00fcbeck"],"department":["Klinik f\u00fcr Kinderchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"W\u00fcnsch","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Schleswig-Holstein Campus L\u00fcbeck, Germany","place":["L\u00fcbeck"],"department":["Klinik f\u00fcr Kinderchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina Karen","family":"Kujath","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Schleswig-Holstein Campus L\u00fcbeck, Germany","place":["L\u00fcbeck"],"department":["Klinik f\u00fcr Kinderchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1530\/EC-25-0798","article-title":"Mapping transition of care for rare endocrine conditions: findings from a cross-sectional survey by the Endo-ERN ToC Working Group","volume":"15","author":"F Carlomagno","year":"2026","journal-title":"Endocr Connect"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1037\/hea0000600","article-title":"Body image and self-esteem in disorders of sex development: A European multicenter study","volume":"37","author":"TC Van De Grift","year":"2018","journal-title":"Health Psychol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"5017","DOI":"10.3390\/ijms20205017","article-title":"Predicting Gonadal Germ Cell Cancer in People with Disorders of Sex Development; Insights from Developmental Biology","volume":"20","author":"LHJ Looijenga","year":"2019","journal-title":"Int J Mol Sci"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.jpurol.2019.04.010","article-title":"Mental health status of individuals with sexual development disorders: A review","volume":"15","author":"M Bohet","year":"2019","journal-title":"J Pediatr Urol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1016\/j.fertnstert.2017.08.013","article-title":"Fertility outcome and information on fertility issues in individuals with different forms of disorders of sex development: findings from the dsd-LIFE study","volume":"108","author":"J S\u0142owikowska-Hilczer","year":"2017","journal-title":"Fertil Steril"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1007\/s00431-009-1086-x","article-title":"Ethical principles and recommendations for the medical management of differences of sex development (DSD)\/intersex in children and adolescents","volume":"169","author":"C Wiesemann","year":"2010","journal-title":"Eur J Pediatr"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2025.102025","article-title":"Strategies for improving the knowledge of patients and carers","volume":"39","author":"U Neumann","year":"2025","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1002\/nau.25305","article-title":"What should be next in lifelong posterior hypospadias: Conclusions from the 2023 ERN eUROGEN and EJP-RD networking meeting","volume":"43","author":"RJM Lammers","year":"2024","journal-title":"Neurourol Urodyn"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1159\/000527433","article-title":"Challenges Waiting for an Adult with DSD","volume":"96","author":"HF Nowotny","year":"2023","journal-title":"Horm Res Paediatr"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/cen.14992","article-title":"Management aspects of congenital adrenal hyperplasia during adolescence and transition to adult care","volume":"101","author":"C Balagamage","year":"2024","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/S2213-8587(13)70138-4","article-title":"Management of adolescents with congenital adrenal hyperplasia","volume":"1","author":"DP Merke","year":"2013","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2025.1600343","article-title":"Molecular pathogenesis, diagnosis, and management challenges in complete androgen insensitivity syndrome","volume":"16","author":"C Wang","year":"2025","journal-title":"Front Endocrinol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2026.02.007","article-title":"Evolution of Gonadal Management in Complete Androgen Insensitivity Syndrome: A 25-Year Retrospective Cohort Study from a Dedicated Differences of Sex Development Service","author":"HI Learner","year":"2026","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2025.114857","article-title":"Perspective on postoperative hormone replacement therapy and fertility preservation in Swyer syndrome with dysgerminoma: a case series and literature review","volume":"317","author":"J Liang","year":"2026","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1097\/MED.0000000000000113","article-title":"Swyer syndrome","volume":"21","author":"TFJ King","year":"2014","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1093\/ejendo\/lvae154","article-title":"Gonadal function and pathology in 17beta-HSD 3 and 5alpha-reductase deficiency","volume":"192","author":"LS Boogers","year":"2025","journal-title":"Eur J Endocrinol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1016\/j.juro.2008.06.043","article-title":"Prostate Screening in Patients With 46,XY Disorders of Sex Development\u2014Is it Necessary?","volume":"180","author":"AH Salmasi","year":"2008","journal-title":"J Urol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/jsxmed\/qdaf382","article-title":"Standardized multidisciplinary care for children and adolescents with differences of sex development: a health intelligence approach","volume":"23","author":"LA Willemsen","year":"2026","journal-title":"J Sex Med"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.jpag.2011.11.003","article-title":"Transition from pediatric to adult care for adolescents and young adults with a disorder of sex development","volume":"25","author":"SE Hullmann","year":"2012","journal-title":"J Pediatr Adolesc Gynecol"}],"container-title":["Aktuelle Urologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2897-1582.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:51:23Z","timestamp":1785451883000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2897-1582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":19,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2026,7,30]]},"published-print":{"date-parts":[[2026,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2897-1582","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0001-7868","1438-8820"],"issn-type":[{"value":"0001-7868","type":"print"},{"value":"1438-8820","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]}}}