{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:06:13Z","timestamp":1783987573675,"version":"3.55.0"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background and study aims Malignant gastric outlet obstruction (MGOO) is a debilitating condition requiring effective palliation. Surgical gastrojejunostomy (SGJ) has been the traditional standard but is associated with relevant morbidity. Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) has emerged as a minimally invasive alternative, though comparative efficacy and safety remain incompletely defined. This systematic review and meta-analysis compared EUS-GE and SGJ for palliative management of MGOO.<\/jats:p>\n                  <jats:p>Methods This review was registered in PROSPERO (CRD420261283768). MEDLINE, Embase, Cochrane CENTRAL, Scopus, and LILACS were searched from January 2015 to October 2025. Random-effects meta-analyses were performed using risk ratios for technical and clinical success, odds ratios for adverse events, serious adverse events, symptom recurrence, reintervention, and 30-day mortality, and mean differences for length of hospital stay. Prespecified subgroup and sensitivity analyses were conducted to assess the robustness of findings.<\/jats:p>\n                  <jats:p>Results Ten studies (two randomized trials and eight observational studies) including 1,087 patients (659 EUS-GE, 428 SGJ) were analyzed. Technical success was comparable between groups. EUS-GE was associated with higher clinical success (RR 1.06; 95% CI 1.01\u20131.12), fewer overall AE (OR 0.35; 95% CI 0.22\u20130.56), and SAE (OR 0.52; 95% CI 0.28\u20130.93). EUS-GE resulted in lower symptom recurrence (OR 0.39; 95% CI 0.18\u20130.85) and shorter LOS (mean difference \u22124.11 days; 95% CI \u22125.29 to \u22122.92). Reintervention rates and 30-day mortality were similar.<\/jats:p>\n                  <jats:p>Conclusions EUS-GE is a safe and effective minimally invasive alternative to SGJ for palliation of MGOO. These findings support the growing role of EUS-GE as a preferred palliative strategy in specialized centers.<\/jats:p>","DOI":"10.1055\/a-2904-9873","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:08:18Z","timestamp":1782860898000},"source":"Crossref","is-referenced-by-count":0,"special_numbering":"S","title":["Endoscopic or Surgical Gastroenterostom for Malignant Gastric Outlet Obstruction: A Systematic Review and Meta-analysis"],"prefix":"10.1055","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0463-5671","authenticated-orcid":false,"given":"Leonardo","family":"Marinho","sequence":"additional","affiliation":[{"name":"Universidade de Fortaleza, CE, Brazil","place":["Fortaleza"],"department":["Postgraduate Studies in Medical Sciences"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6029-8781","authenticated-orcid":false,"given":"Alessandrino T.","family":"de 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