{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T23:27:55Z","timestamp":1786663675044,"version":"build-2736575974"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The primary objective of breast-conserving surgery (BCS) is complete excision of the tumor with histologically negative margins (R0 resection). Intraoperative ultrasound (IOUS) has been shown to reduce re-excision rates (R1) for sonographically visible breast cancer. However, a standardized IOUS technique has not yet been established. This study aimed to evaluate whether standardization using the \u201cT\u00fcbingen Ultrasound Ruler\u201d can reduce R1 resection rates.<\/jats:p>\n                  <jats:p>This retrospective study included 273 patients who underwent BCS between January 2020 and December 2023 for unilateral or bilateral ductal carcinoma in situ and\/or invasive breast cancer, regardless of tumor biology, the presence of microcalcifications, or prior chemotherapy. All surgeries were performed by a single surgeon. Tumors were excised with a sonographically assessed margin of &gt;10 mm in all directions. After specimen imaging, additional margin shavings were obtained when indicated.<\/jats:p>\n                  <jats:p>A total of 282 specimens were analyzed, with a mean specimen weight of 110.5 g. Considering the main resection specimen alone, the R1 rate was 18.8%. Targeted IOUS-guided shavings significantly reduced the R1 rate to 8.5%. Compared with the mean R1 rate of the average figures of OnkoZert-certified breast centers reported between 2020 and 2023 (12.34%), the use of the \u201cT\u00fcbingen Ultrasound Ruler\u201d in combination with specimen imaging was associated with a significantly lower R1 rate (p = 0.043).<\/jats:p>\n                  <jats:p>Standardization of the IOUS technique combined with imaging-guided targeted shavings makes it possible to achieve a low R1 rate (8.5%) in breast-conserving surgery.<\/jats:p>","DOI":"10.1055\/a-2908-7510","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T22:53:55Z","timestamp":1786661635000},"source":"Crossref","is-referenced-by-count":0,"title":["Impact of Standardized Intraoperative Ultrasound on Re-excision Rates in Breast-Conserving Surgery"],"prefix":"10.1055","clinical-trial-number":[{"clinical-trial-number":"nct07519668","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5238-7521","authenticated-orcid":false,"given":"Bettina","family":"Boeer","sequence":"additional","affiliation":[{"name":"University Hospital T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Department of Women's Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Seltenreich","sequence":"additional","affiliation":[{"name":"University Hospital T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Department of Women's Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitt","family":"Sch\u00f6nfisch","sequence":"additional","affiliation":[{"name":"University Hospital T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Department of Women's Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8837-8758","authenticated-orcid":false,"given":"Selin","family":"Guergan","sequence":"additional","affiliation":[{"name":"University Hospital T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Department of Women's Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Gruber","sequence":"additional","affiliation":[{"name":"University Hospital T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Department of Women's Health"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannik","family":"Kandzi","sequence":"additional","affiliation":[{"name":"University Hospital T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Department of Women's 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