{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:56:36Z","timestamp":1791240996261,"version":"4.1.0"},"reference-count":58,"publisher":"Georg Thieme Verlag KG","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Die Schmerztherapie hat mittlerweile eine immens hohe Bedeutung in der klinischen Praxis erlangt und ist nicht mehr wegzudenken, so vor allem im Hinblick auf ein suffizientes perioperatives\/-interventionelles Fallmanagement als auch im Vorgehen bei bestimmten (Problem-)Diagnosen (Diagnosefeldern), Syndromen bzw. Symptomkonstellationen.<\/jats:p>\n                  <jats:p>Gew\u00e4hrleistung eines schnellen, standardisierten Zugriffs durch kompetente Entwicklung einer kompakten \u201eStandard Operating Procedure\u201c (SOP) zur interdisziplin\u00e4ren und mit breitem Diagnoseprofil aufgestellten Schmerztherapie bei Tumorpatienten eines subspezialisierten Zentrums, basierend auf i) Erfahrungen aus langj\u00e4hriger klinischer Praxis sowie ii) aktuellen Referenzen der medizinisch-wissenschaftlichen Literatur (ohne Vorab-Publikationen und Lehrbuchinhalte komplett ersetzen zu wollen).<\/jats:p>\n                  <jats:p>Narrative Kurz\u00fcbersicht zur \u201eSOP \u2013 Schmerztherapie bei Tumorerkrankungen\/-patienten\u201c (als QR-Code-basierter Anhang).<\/jats:p>\n                  <jats:p>Bei Tumorschmerzen sind Opioide die prim\u00e4r zu erw\u00e4gende Medikamentengruppe. Eingeschr\u00e4nkt wird die Opioid-Anwendung durch Leber- bzw. Niereninsuffizienz, Art des Opioids (Tapentadol wirkt nicht ausreichend), weitere Kontraindikationen (Morphinsulfat bei \u201echronic obstructive pulmonary disease\u201c [COPD]) bzw. Art der Applikation (Patienten k\u00f6nnen nicht schlucken oder sind bewusstseinsgest\u00f6rt). Bei Patienten mit Tumorschmerz ist immer auch nach Angst zu fragen.<\/jats:p>\n                  <jats:p>Bereits vor Jahren wurden von der interdisziplinar besetzten Arbeitsgruppe des Universit\u00e4tsklinikums Magdeburg A. o. R. SOP\u2019s zur Diagnose-bezogenen und perioperativen\/-interventionellen Schmerztherapie in der Allgemein- und Viszeralchirurgie sowie Gef\u00e4\u00dfchirurgie\/-medizin etabliert.<\/jats:p>\n                  <jats:p>Tumorschmerzen geh\u00f6ren neben den Geburtsschmerzen und den postoperativen Schmerzen zu den am besten beherrschbaren Schmerzformen. Dies ist eine Aufforderung zum Handeln. Dabei geht es um die konsequente, ad\u00e4quate, ausreichend dosierte Gabe von Medikamenten des WHO-Schemas (WHO I dabei nicht zwingend), von Psychopharmaka sowie nichtmedikament\u00f6sen Verfahren.<\/jats:p>","DOI":"10.1055\/a-2911-5864","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:40:45Z","timestamp":1791240045000},"page":"1132-1144","source":"Crossref","is-referenced-by-count":0,"title":["\u201eStandard Operating Procedure\u201c (SOP) \u2013 Schmerztherapie bei Tumorkonstellationen"],"prefix":"10.1055","volume":"151","author":[{"given":"Michael","family":"Brinkers","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Schmerztherapie; Klinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie; Otto-von-Guericke-Universit\u00e4t mit Universit\u00e4tsklinikum; Magdeburg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giselher","family":"Pfau","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Schmerztherapie; Klinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie; Otto-von-Guericke-Universit\u00e4t mit Universit\u00e4tsklinikum; Magdeburg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Bergner","sequence":"additional","affiliation":[{"name":"Bereich Palliativmedizin; Klinik f\u00fcr An\u00e4sthesiologie und Intensivtherapie; Otto-von-Guericke-Universit\u00e4t mit Universit\u00e4tsklinikum; Magdeburg, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0402-0626","authenticated-orcid":false,"given":"Frank","family":"Meyer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Allgemein-, Viszeral-, Gef\u00e4\u00df- und Transplantationschirurgie; Otto-von-Guericke-Universit\u00e4t mit Universit\u00e4tsklinikum, GERMANY","place":["Magdeburg"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1007\/s00761-023","article-title":"SOP \u2013 Schmerztherapie bei Patienten mit einer Tumorerkrankung in Palliativsituation","volume":"29","author":"B Dasch","year":"2023","journal-title":"Die Onkologie"},{"key":"ref2","volume-title":"Tumorschmerz","author":"W Larbig","year":"2002"},{"key":"ref3","first-page":"16","author":"M Brinkers","year":"2017"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1007\/s00772-024-01158-w","article-title":"Moderne medikament\u00f6se Schmerztherapie \u2013 was der Gef\u00e4\u00dfchirurg dar\u00fcber wissen sollte anhand einer einrichtungsspezifischen SOP","volume":"29","author":"M Brinkers","year":"2024","journal-title":"Gef\u00e4sschirurgie"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"591","DOI":"10.3390\/cancers15030591","article-title":"Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis","volume":"15","author":"RAH Snijders","year":"2023","journal-title":"Cancers (Basel)"},{"key":"ref6","first-page":"229","volume-title":"Tumorschmerz","author":"HA Schele","year":"1997"},{"key":"ref7","volume-title":"Tumorschmerztherapie","author":"U Hankemeier","year":"2000"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"iv166","DOI":"10.1093\/annonc\/mdy152","article-title":"Management of cancer pain in adult patients: ESMO Clinical Practice Guidelines","volume":"29","author":"M Fallon","year":"2018","journal-title":"Ann Oncol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"e39","DOI":"10.1055\/s-0041-111219","article-title":"Pain therapy in in-patients with cancer. 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