{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:00:18Z","timestamp":1785279618679,"version":"3.55.0"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","funder":[{"DOI":"10.13039\/100018693","name":"HORIZON EUROPE","doi-asserted-by":"crossref","award":["HORIZON-HLTH-2022-TOOL-11-01"],"award-info":[{"award-number":["HORIZON-HLTH-2022-TOOL-11-01"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In patients with unprovoked venous thromboembolism (VTE), indefinite anticoagulation is recommended to prevent recurrence but may expose some patients to unnecessary long-term bleeding risk. Current clinical scores and biomarkers have limited discriminative performance, do not capture the time-dependent nature of VTE, and do not incorporate patients' perspectives or support shared decision-making.<\/jats:p>\n                  <jats:p>To develop and validate time-dependent, multicomponent risk prediction scores and socio-anthropological scales (TDMI) integrated in a shared decision-making process to optimize long-term anticoagulation management after unprovoked VTE.<\/jats:p>\n                  <jats:p>MORPHEUS is an international, multidisciplinary research programme conducted in eight European countries. The TDMI will combine clinical, biological, imaging, and pharmacological biomarkers with socio-anthropological scales reflecting patients' lived experiences, preferences, and perceptions of risk. Candidate components will be identified through systematic literature review, Delphi consensus, qualitative interviews with patients and physicians, and pooled analyses of large prospective European VTE cohorts including clinical outcomes, biobanks, and imaging data. Dynamic, multi-level, time-dependent prediction models for recurrent VTE and anticoagulant-related bleeding will be derived using advanced statistical and machine-learning approaches. The clinical effectiveness and acceptability of TDMI integrated in a shared decision-making process will be evaluated in a stepped-wedge cluster randomized trial enrolling 2,400 patients with a first unprovoked VTE.<\/jats:p>\n                  <jats:p>The TDMI is expected to improve individualized risk stratification, reduce unnecessary extended anticoagulation, lower bleeding complications, and improve patient satisfaction, treatment adherence, and quality of life.<\/jats:p>\n                  <jats:p>The MORPHEUS project will support personalized anticoagulation decisions and improve long-term outcomes in patients after unprovoked VTE.<\/jats:p>","DOI":"10.1055\/a-2913-2857","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:51:42Z","timestamp":1784069502000},"source":"Crossref","is-referenced-by-count":0,"title":["Prognosis Prediction and Shared Decision-Making for Personalized Anticoagulant Therapy after Unprovoked Venous Thromboembolism: The MORPHEUS Project"],"prefix":"10.1055","clinical-trial-number":[{"clinical-trial-number":"nct06731244","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Francis","family":"Couturaud","sequence":"additional","affiliation":[{"name":"Brest University Hospital Centre, Bretagne, France","place":["Brest"],"department":["Department of Internal Medicine and Chest Diseases"]},{"name":"INSERM U1304 GETBO (Groupe d'\u00c9tude de la Thrombose de Bretagne Occidentale), Univ Brest, Bretagne, France","place":["Brest"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4571-7721","authenticated-orcid":false,"given":"David","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Ram\u00f3n y Cajal Hospital, IRYCIS and Alcal\u00e1 de Henares University, Madrid, Spain","place":["Madrid"],"department":["Department of Medicine, Division of Respiratory"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Descartes, Sorbonne Paris Cit\u00e9, and INSERM UMR S 1140, France, France","place":["Paris"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Turrini","sequence":"additional","affiliation":[{"name":"Institute of Public Goods and Policies, Consejo Superior de Investigaciones Cient\u00edficas Instituto de Ciencias Agrarias, Community of Madrid, Spain","place":["Madrid"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Odeberg","sequence":"additional","affiliation":[{"name":"KTH Royal Institute of Technology, Sweden","place":["Stockholm"],"department":["Department of Protein Science"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9961-0754","authenticated-orcid":false,"given":"Frederikus A.","family":"Klok","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center, Zud-Holland, Netherlands","place":["Leiden"],"department":["Department of Thrombosis and Hemostasis"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Presles","sequence":"additional","affiliation":[{"name":"Inserm CIE3, CHU Saint Etienne, Loire, France","place":["Saint Etienne"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Bourgain","sequence":"additional","affiliation":[{"name":"Inserm988, CERMES3, \u00cele-de-France, France","place":["Villejuif"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6359-7279","authenticated-orcid":false,"given":"Stavros V.","family":"Konstantinides","sequence":"additional","affiliation":[{"name":"University Medical Centre, Johannes Gutenberg University Mainz, n\/a, Germany","place":["Mainz"],"department":["Centre for Thrombosis and Haemostasis"]},{"name":"University Medical Centre, Johannes Gutenberg University Mainz, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menno V.","family":"Huisman","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center, North Holland, Netherlands","place":["Leiden"],"department":["Department of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre Emmanuel","family":"Morange","sequence":"additional","affiliation":[{"name":"Inserm, France, France","place":["Marseille"],"department":["Department of Hematology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Germain","sequence":"additional","affiliation":[{"name":"Inserm U1219, Universit\u00e9 Bordeaux 1, Nouvelle-Aquitaine, France","place":["Bordeaux"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette N.","family":"Svendsen","sequence":"additional","affiliation":[{"name":"University of Copenhagen, Faculty of Health and Medical Sciences, Capital Region of Denmark, Denmark","place":["Copenhagen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Ollier","sequence":"additional","affiliation":[{"name":"Univ Lyon, France","place":["Saint-Etienne"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecile","family":"Tromeur","sequence":"additional","affiliation":[{"name":"Brest University Hospital, Brittany, France","place":["BREST"],"department":["EA 3878 (GETBO), Department of Internal Medicine and Chest Diseases"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Yves","family":"Salaun","sequence":"additional","affiliation":[{"name":"Brest University Hospital, Brittany, France","place":["Brest"],"department":["Department of Nuclear Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Alexandre","family":"Tregouet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Bordeaux, INSERM UMR 1219, Bordeaux Population Health Research Centre, France","place":["Bordeaux"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarhan","family":"Yaiche","sequence":"additional","affiliation":[{"name":"European Clinical Research Infrastructure Network, \u00cele-de-France, France","place":["Paris"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette","family":"Bresson Ladegaard Knox","sequence":"additional","affiliation":[{"name":"University of Copenhagen, Faculty of Health and Medical Sciences, Capital Region of Denmark, Denmark","place":["Copenhagen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Munsch","sequence":"additional","affiliation":[{"name":"INSERM U1304 GETBO (Groupe d'\u00c9tude de la Thrombose de Bretagne Occidentale), Univ Brest, Bretagne, France","place":["Brest"]},{"name":"Brest University Hospital Centre, Bretagne, France","place":["Brest"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Fortin-Prunier","sequence":"additional","affiliation":[{"name":"INSERM1304, Brest University Hospital Centre, Bretagne, France","place":["Brest"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Righini","sequence":"additional","affiliation":[{"name":"Geneva University Hospitals and Faculty of Medicine, Gen\u00e8ve, Switzerland","place":["Geneve"],"department":["Department of Medicine, Division of Angiology and Hemostasis"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Pruszczyk","sequence":"additional","affiliation":[{"name":"The Medical University of Warsaw, mazowieckie, Poland","place":["Warszawa"],"department":["Department of Internal Medicine & Cardiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Schreiber","sequence":"additional","affiliation":[{"name":"Danish Hospital for Rheumatic Diseases, Denmark","place":["S\u00f8nderborg"]},{"name":"University of Southern Denmark, Syddanmark, Denmark","place":["Odense"],"department":["Department of Regional Health Research"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tijana","family":"Patteri","sequence":"additional","affiliation":[{"name":"Todaytomorrow, Netherlands","place":["Rotterdam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Van de Merwe","sequence":"additional","affiliation":[{"name":"Todaytomorrow, Netherlands","place":["Rotterdam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Camilleri","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center, ZH, Netherlands","place":["Leiden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Eikenboom","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center, ZH, Netherlands","place":["Leiden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothea","family":"Becker","sequence":"additional","affiliation":[{"name":"Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Rhineland-Palatine, Germany","place":["Mainz"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Martin","sequence":"additional","affiliation":[{"name":"Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Rhineland-Palatine, Germany","place":["Mainz"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brieg","family":"Dissaux","sequence":"additional","affiliation":[{"name":"Brest University Hospital Centre, Bretagne, France","place":["Brest"],"department":["Department of Internal Medicine and Chest Diseases"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bourhis","sequence":"additional","affiliation":[{"name":"Brest University Hospital Centre, Bretagne, France","place":["Brest"],"department":["Department of Nuclear Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Bertoletti","sequence":"additional","affiliation":[{"name":"CHU Saint-\u00c9tienne, Rh\u00f4ne-Alpes, France","place":["Saint-Etienne"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Fischer","sequence":"additional","affiliation":[{"name":"Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Rhineland-Palatine, Germany","place":["Mainz"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Murano","sequence":"additional","affiliation":[{"name":"Universidad Complutense de Madrid, Community of Madrid, Spain","place":["Madrid"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Hartlev","sequence":"additional","affiliation":[{"name":"Faculty of Law, University of Copenhagen, Capital Region of Denmark, Denmark","place":["Copenhagen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia","family":"Hurst","sequence":"additional","affiliation":[{"name":"Institute for Biomedical Ethics, Universit\u00e9 de Gen\u00e8ve, GE, Switzerland","place":["Geneva"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvy","family":"Laporte","sequence":"additional","affiliation":[{"name":"CHU Saint-Etienne, France","place":["Saint-Etienne"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Lemari\u00e9","sequence":"additional","affiliation":[{"name":"INSERM U1304 GETBO (Groupe d'\u00c9tude de la Thrombose de Bretagne Occidentale), Univ Brest, Bretagne, France","place":["Brest"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"issue":"11","key":"ref1","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1161\/ATVBAHA.114.304488","article-title":"Thrombosis: a major contributor to global disease burden","volume":"34","author":"G E Raskob","year":"2014","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"04","key":"ref2","first-page":"756","article-title":"Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality","volume":"98","author":"A T Cohen","year":"2007","journal-title":"Thromb Haemost"},{"issue":"43","key":"ref3","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1093\/eurheartj\/ehu283","article-title":"2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism","volume":"35","author":"S V Konstantinides","year":"2014","journal-title":"Eur Heart J"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.thromres.2014.07.002","article-title":"Treatment patterns of venous thromboembolism in a real-world population: the Q-VTE study cohort","volume":"134","author":"V Tagalakis","year":"2014","journal-title":"Thromb Res"},{"issue":"05","key":"ref5","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1160\/TH16-03-0205","article-title":"Current incidence of venous thromboembolism and comparison with 1998: a community-based study in Western France","volume":"116","author":"A Delluc","year":"2016","journal-title":"Thromb Haemost"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1001\/jama.2015.7046","article-title":"Six months vs extended oral anticoagulation after a first episode of pulmonary embolism: the PADIS-PE randomized clinical trial","volume":"314","author":"F Couturaud","year":"2015","journal-title":"JAMA"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"l4363","DOI":"10.1136\/bmj.l4363","article-title":"Long term risk of symptomatic recurrent venous thromboembolism after discontinuation of anticoagulant treatment for first unprovoked venous thromboembolism event: systematic review and meta-analysis","volume":"366","author":"F Khan","year":"2019","journal-title":"BMJ"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.chest.2015.11.026","article-title":"Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report","volume":"149","author":"C Kearon","year":"2016","journal-title":"Chest"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/bcpt.13625","article-title":"Effectiveness and safety of oral anticoagulation treatment beyond 1 year after venous thromboembolism in patients at intermediate recurrence risk","volume":"129","author":"S P Johnsen","year":"2021","journal-title":"TBasic Clin Pharmacol Toxicol"},{"issue":"11","key":"ref10","doi-asserted-by":"crossref","first-page":"893","DOI":"10.7326\/0003-4819-139-11-200312020-00007","article-title":"Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: a meta-analysis","volume":"139","author":"L A Linkins","year":"2003","journal-title":"Ann Intern Med"},{"issue":"08","key":"ref11","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJMoa1113697","article-title":"Extended use of dabigatran, warfarin, or placebo in venous thromboembolism","volume":"368","author":"S Schulman","year":"2013","journal-title":"N Engl J Med"},{"issue":"26","key":"ref12","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1056\/NEJMoa1007903","article-title":"Oral rivaroxaban for symptomatic venous thromboembolism","volume":"363","author":"R Bauersachs","year":"2010","journal-title":"N Engl J Med"},{"issue":"10","key":"ref13","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1160\/TH13-02-0132","article-title":"Dynamics of case-fatality rates of recurrent thromboembolism and major bleeding in patients treated for venous thromboembolism","volume":"110","author":"R Lecumberri","year":"2013","journal-title":"Thromb Haemost"},{"issue":"10","key":"ref14","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.7326\/M21-1094","article-title":"Long-term risk for major bleeding during extended oral anticoagulant therapy for first unprovoked venous thromboembolism: a systematic review and meta-analysis","volume":"174","author":"F Khan","year":"2021","journal-title":"Ann Intern Med"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0140-6736(24)02842-3","article-title":"Extended treatment of venous thromboembolism with reduced-dose versus full-dose direct oral anticoagulants in patients at high risk of recurrence: a non-inferiority, multicentre, randomised, open-label, blinded endpoint trial","volume":"405","author":"F Couturaud","year":"2025","journal-title":"Lancet"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"j1065","DOI":"10.1136\/bmj.j1065","article-title":"Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study","volume":"356","author":"M A Rodger","year":"2017","journal-title":"BMJ"},{"issue":"05","key":"ref17","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1183\/13993003.00280-2016","article-title":"Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment","volume":"48","author":"F A Klok","year":"2016","journal-title":"Eur Respir J"},{"issue":"05","key":"ref18","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.3390\/jcm9051582","article-title":"Predicting the risk of recurrent venous thromboembolism: current challenges and future opportunities","volume":"9","author":"H Stevens","year":"2020","journal-title":"J Clin Med"},{"issue":"09","key":"ref19","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1111\/jth.14535","article-title":"Risk prediction of recurrent venous thrombosis; where are we now and what can we add?","volume":"17","author":"J F Timp","year":"2019","journal-title":"J Thromb Haemost"},{"issue":"11","key":"ref20","doi-asserted-by":"crossref","first-page":"e0142070","DOI":"10.1371\/journal.pone.0142070","article-title":"A qualitative study to appraise patients and family members perceptions, knowledge, and attitudes towards venous thromboembolism risk","volume":"10","author":"C Haxaire","year":"2015","journal-title":"PLoS One"},{"key":"ref21","volume-title":"Shared decision making","author":"National Institute for Health and Care Excellence (NICE)","year":"2021"},{"issue":"09","key":"ref22","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1111\/jth.14534","article-title":"Predicting the risk of recurrent venous thrombosis: what the future might bring","volume":"17","author":"W M Lijfering","year":"2019","journal-title":"J Thromb Haemost"},{"issue":"15","key":"ref23","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1182\/bloodadvances.2022007027","article-title":"Predicting major bleeding during extended anticoagulation for unprovoked or weakly provoked venous thromboembolism","volume":"6","author":"P S Wells","year":"2022","journal-title":"Blood Adv"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"112903","DOI":"10.1016\/j.socscimed.2020.112903","article-title":"Genomic susceptibility in practice: the regulatory trajectory of non-rare thrombophilia (NRT) genetic tests in the clinical management of venous thrombo-embolism (VTE)","volume":"304","author":"M Turrini","year":"2022","journal-title":"Soc Sci Med"},{"key":"ref25","volume-title":"Constructing Grounded Theory","author":"K Charmaz","year":"2014","edition":"2nd ed."},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1111\/j.1475-6773.2005.00438.x","article-title":"Development and testing of a short form of the patient activation measure","volume":"40","author":"J H Hibbard","year":"2005","journal-title":"Health Serv Res"},{"issue":"12","key":"ref27","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.1111\/j.1538-7836.2010.04092.x","article-title":"A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolism","volume":"8","author":"G Antoni","year":"2010","journal-title":"J Thromb Haemost"},{"issue":"07","key":"ref28","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.3324\/haematol.2018.210971","article-title":"Six months versus two years of oral anticoagulation after a first episode of unprovoked deep-vein thrombosis","volume":"104","author":"F Couturaud","year":"2019","journal-title":"Haematologica"}],"container-title":["Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2913-2857.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T22:41:56Z","timestamp":1785278516000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2913-2857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,14]]},"references-count":28,"URL":"https:\/\/doi.org\/10.1055\/a-2913-2857","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0340-6245","2567-689X"],"issn-type":[{"value":"0340-6245","type":"print"},{"value":"2567-689X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,7,14]]},"published":{"date-parts":[[2026,7,14]]}}}