{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:56:56Z","timestamp":1791241016709,"version":"4.1.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Neoplasien erh\u00f6hen das Risiko f\u00fcr Infektionen \u2013 Haupttodesursachen sind Pneumonien und Influenza-Infektionen. Streptococcus pneumoniae als h\u00e4ufigster Erreger der ambulant erworbenen Pneumonie ist bei Patient*innen mit h\u00e4matologischen Neoplasien, die eine 30 Mal so hohe Inzidenz invasiver Pneumokokken-Erkrankungen wie die Allgemeinbev\u00f6lkerung aufweisen, von gro\u00dfer Bedeutung. Die Impfung als Pr\u00e4vention nimmt eine Schl\u00fcsselrolle ein. Die st\u00e4ndige Impfkommission (STIKO) empfiehlt diese \u00fcber 60-J\u00e4hrigen und immunsupprimierten Erwachsenen. Nur ca. 20% dieser Personen sind jedoch geimpft.<\/jats:p>\n                  <jats:p>Relevanz von Pneumokokken-Impfungen bei Krebspatient*innen und Herausforderungen der praktischen Umsetzung.<\/jats:p>\n                  <jats:p>Kasuistik des klinischen Verlaufs einer h\u00e4matologischen Patientin mit rezidivierenden Pneumokokken-Infektionen.<\/jats:p>\n                  <jats:p>Invasive Pneumokokken-Erkrankungen gehen bei Krebspatient*innen mit hoher Morbidit\u00e4t und Mortalit\u00e4t einher und sind potenziell impfpr\u00e4ventabel. F\u00fcr dieses Kollektiv existieren angepasste Empfehlungen.<\/jats:p>\n                  <jats:p>Eine hohe Aufmerksamkeit f\u00fcr das Risiko von Pneumokokken-Infektionen bei Krebspatient*innen kann die Impfraten erh\u00f6hen. Eine Abstimmung zwischen den Versorgungssektoren ist essenziell, um die Empfehlungen umzusetzen.<\/jats:p>","DOI":"10.1055\/a-2913-3604","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:40:45Z","timestamp":1791240045000},"page":"1127-1131","source":"Crossref","is-referenced-by-count":0,"title":["Rezidivierende Pneumokokken-Infektionen bei immunsupprimierter Patientin mit letalem Verlauf"],"prefix":"10.1055","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2332-7169","authenticated-orcid":false,"given":"Jonathan M.","family":"Steinke","sequence":"additional","affiliation":[{"name":"Uniklinik K\u00f6ln Klinik I fur Innere Medizin, Nordrhein-Westfalen, GERMANY","place":["K\u00f6ln"],"department":["H\u00e4matologie, Onkologie und Klinische Infektiologie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Schneitler","sequence":"additional","affiliation":[{"name":"Universit\u00e4t zu K\u00f6ln, Medizinische Fakult\u00e4t und Uniklinik K\u00f6ln, Institut f\u00fcr Medizinische Mikrobiologie, Immunologie und Hygiene"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibylle C.","family":"Mellinghoff","sequence":"additional","affiliation":[{"name":"- Universit\u00e4t zu K\u00f6ln, Medizinische Fakult\u00e4t und Uniklinik K\u00f6ln, Klinik I f\u00fcr Innere Medizin sowie Translationale Forschung, Cologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1097\/COC.0000000000001182","article-title":"Death From Infection Among Patients Living With Cancer","volume":"48","author":"M Chiam","year":"2025","journal-title":"Am J Clin Oncol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1007\/s40121-021-00433-7","article-title":"Fatal Infections Among Cancer Patients: A Population-Based Study in the United States","volume":"10","author":"Y Zheng","year":"2021","journal-title":"Infect Dis Ther"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.ijid.2021.03.072","article-title":"Invasive pneumococcal disease among adults with hematological and solid organ malignancies: A population-based cohort study","volume":"106","author":"HM Garcia Garrido","year":"2021","journal-title":"Int J Infect Dis"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"3","DOI":"10.25646\/11719.2","article-title":"Aktualisierung der Empfehlungen der STIKO zur Standardimpfung von Personen \u226560 Jahre sowie  zur Indikationsimpfung von Risikogruppen gegen  Pneumokokken und die dazugeh\u00f6rige wissenschaftliche Begr\u00fcndung","author":"J Schlaberg","year":"2023","journal-title":"Epidemiologisches Bulletin"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2018.23.16.17-00454,","article-title":"Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): Results from the burden of communicable diseases in Europe study, European Union and European economic countries, 2009 to 2013","volume":"23","author":"A Cassini","year":"2018","journal-title":"Eurosurveillance"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1055\/s-0032-1310103","article-title":"The Burden of Pneumococcal Pneumonia-Experience of the German Competence Network CAPNETZ Epidemiologie, Klinik und Verlauf der Pneumokokkenpneumonie-Daten aus CAPNETZ","volume":"66","author":"MW Pletz","year":"2012","journal-title":"Pneumologie"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e171","DOI":"10.1016\/j.clml.2022.12.003","article-title":"Rates of Influenza and Pneumococcal Vaccination and Correlation With Survival in Multiple Myeloma Patients","volume":"23","author":"MA Thompson","year":"2023","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e1009389","DOI":"10.1371\/JOURNAL.PCBI.1009389","article-title":"Analysing pneumococcal invasiveness using Bayesian models of pathogen progression rates","volume":"18","author":"A L\u00f8chen","year":"2022","journal-title":"PLoS Comput Biol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"163","DOI":"10.3324\/haematol.2024.285645","article-title":"Risk of infections in multiple myeloma. 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