{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:43:09Z","timestamp":1792449789869,"version":"4.5.0"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Es erfolgte die Aufnahme einer 93-j\u00e4hrigen, sarkopenen Patientin nach Sturz und konservativ behandelter Os sacrum Fraktur in die geriatrische Abteilung zur weiteren Therapie und Diagnostik. Klinisch zeigt sich vor allem eine Appetitlosigkeit mit \u00dcbelkeit und rezidivierendem Erbrechen. In einer Vorklinik wurde bereits die Diagnose eines Traktionsdivertikels gestellt. Im weiteren Verlauf kam es zu einer fortschreitenden Gewichtsabnahme mit Schw\u00e4che und zuletzt Sturz und damit einhergehender Os sacrum Fraktur.<\/jats:p>\n                  <jats:p>In der klinisch-neurologischen Untersuchung zeigte sich bis auf eine fortgeschrittene Frailty (nach Frailty Scala: \u201e7\u201c als \u201eausgepr\u00e4gt frail\u201c 1) ein unauff\u00e4lliger Befund.<\/jats:p>\n                  <jats:p>In einer Breischluck-Untersuchung zeigte sich der dringende Verdacht auf eine distale Motilit\u00e4tsst\u00f6rung des \u00d6sophagus im Sinne eines \u00d6sophagussphinkterspasmus. Aufgrund der Multimorbidit\u00e4t und des Patientenwillens wurde sich auf ein konservatives Prozedere mittels Botulinumtoxininjektionen verst\u00e4ndigt. Hierunter kam es bereits kurzfristig zu einer Verbesserung der Symptomatik.<\/jats:p>\n                  <jats:p>Eine Dysphagie kann zu einem schwerwiegenden Gewichtsverlust mit damit einhergehender Sarkopenie und Frailty f\u00fchren. Dies kann zu weiteren Komplikationen wie St\u00fcrzen und Frakturen wie in unserem Beispiel f\u00fchren. Eine gezielte Diagnostik und Therapie ist damit unumg\u00e4nglich, um diesen Teufelskreis zu durchbrechen.<\/jats:p>","DOI":"10.1055\/a-2915-3435","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:30:28Z","timestamp":1792449028000},"page":"1185-1189","source":"Crossref","is-referenced-by-count":0,"title":["Distaler \u00d6sophagusspasmus als seltene Ursache f\u00fcr einen zunehmenden k\u00f6rperlichen Abbau mit Mangelern\u00e4hrung, Sarkopenie und Frailty"],"prefix":"10.1055","volume":"151","author":[{"given":"Jonas","family":"Klein","sequence":"additional","affiliation":[{"name":"Abt. f. Geriatrie mit Neurologie und Tagesklinik, Johanniter-Krankenhaus Bonn, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udo","family":"Karp","sequence":"additional","affiliation":[{"name":"Abt. f. 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