{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T05:58:22Z","timestamp":1785218302933,"version":"3.55.0"},"reference-count":124,"publisher":"Georg Thieme Verlag KG","funder":[{"name":"NIGMS of the NIH","award":["U54GM115428"],"award-info":[{"award-number":["U54GM115428"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"abstract":"<jats:p>The coronavirus disease 2019 (COVID-19) pandemic fundamentally disrupted health care systems worldwide, with disproportionate consequences for maternal and newborn health. Pregnant individuals and neonates faced both direct clinical consequences of severe acute respiratory syndrome\u2013coronavirus-2 (SARS-CoV-2) infection and indirect effects of health system disruption. This narrative review synthesizes global evidence on the pandemic's impact on perinatal outcomes, neonatal care, breastfeeding practices, and financial burden on health care institutions, contrasting high-income countries (HICs) and low- and middle-income countries (LMICs). PubMed, the World Health Organization (WHO), the American Academy of Pediatrics (AAP), and the Centers for Disease Control and Prevention (CDC) databases were searched for peer-reviewed publications through early 2026. The pandemic increased maternal mortality, stillbirth, and neonatal morbidity, particularly in LMICs, alongside paradoxical preterm birth reductions in some HICs. Vertical SARS-CoV-2 transmission remained infrequent. Neonatal admissions fell while acuity and length of stay increased. Breastfeeding was profoundly disrupted by inconsistent separation policies and infection control measures. Health care institutions absorbed substantial additional costs from screening programs and care pathway reorganization. COVID-19 exposed and exacerbated existing global health inequities in maternal and neonatal care. Evidence-based, context-sensitive policies from the WHO, AAP, and CDC are essential to preserve perinatal care quality during future health emergencies.<\/jats:p>","DOI":"10.1055\/a-2918-3933","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T23:21:00Z","timestamp":1784589660000},"source":"Crossref","is-referenced-by-count":0,"title":["COVID-19 and Global Perinatal Health: Lessons Learned on Maternal-Neonatal Outcomes, Infant Feeding Practices, and Health Care Economics across Income Settings"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1263-1822","authenticated-orcid":false,"given":"Vignesh","family":"Gunasekaran","sequence":"first","affiliation":[{"name":"West Virginia University School of Medicine, West Virginia, United States","place":["Martinsburg"],"department":["Department of Pediatrics, Division of Neonatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4038-7673","authenticated-orcid":false,"given":"Soowan","family":"Woo","sequence":"first","affiliation":[{"name":"SUNY Downstate Health Sciences University, New York, United States","place":["New York"],"department":["Department of Pediatrics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash K.","family":"Shetty","sequence":"additional","affiliation":[{"name":"Atrium Health Wake Forest Baptist, Wake Forest School of Medicine, North Carolina, United States","place":["Winston-Salem"],"department":["Department of Pediatrics\/Infectious Disease"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kaufman","sequence":"additional","affiliation":[{"name":"University of Virginia School of Medicine, Virginia, United States","place":["Charlottesville"],"department":["Department of Pediatrics, Division of Neonatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvesh Mohan","family":"Garg","sequence":"additional","affiliation":[{"name":"Atrium Health Wake Forest Baptist, Wake Forest School of Medicine, North Carolina, United States","place":["Winston-Salem"],"department":["Department of Pediatrics, Division of Neonatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"issue":"11","key":"ref1","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jama.2020.1585","article-title":"Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China","volume":"323","author":"D Wang","year":"2020","journal-title":"JAMA"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"e759","DOI":"10.1016\/S2214-109X(21)00079-6","article-title":"Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a 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