{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:51:39Z","timestamp":1791366699118,"version":"4.3.1"},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Musculoskelet Radiol"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:p>A 15-year-old male with no significant medical history presented with a 4-month history of bilateral wrist pain and a 2-month history of rapidly growing, spontaneously ulcerating bilateral volar wrist nodules. He denied fevers, fatigue, weight loss, illicit drug use\/injection, or local trauma including self-harming behavior. Ultrasound and MRI demonstrated strikingly symmetric ill-defined mass-like tissue underlying each wound invading the bilateral distal radii but without mass effect or invasion of traversing bilateral radial arteries and flexor carpi radialis tendons. Imaging of the pelvis and spine revealed multifocal thoracolumbar spine and right proximal femoral involvement. Excisional biopsy of the wrist lesions demonstrated an active inflammatory process with broad-based budding yeast confirmed to be Blastomyces spp. on fungal cultures. The case herein describes an uncommon example of disseminated blastomycosis osseous and soft tissue infection without pulmonary involvement.<\/jats:p>","DOI":"10.1055\/a-2924-0545","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T22:52:42Z","timestamp":1788994362000},"page":"660-662","source":"Crossref","is-referenced-by-count":0,"title":["Multifocal Osseous and Soft Tissue Blastomycosis Infection"],"prefix":"10.1055","volume":"30","author":[{"given":"Sean M.","family":"Rodich","sequence":"additional","affiliation":[{"name":"University of Virginia, Virginia, United States","place":["Charlottesville"],"department":["Department of Musculoskeletal Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen A.","family":"Atkins","sequence":"additional","affiliation":[{"name":"University of Virginia, Virginia, United States","place":["Charlottesville"],"department":["Department of Pathology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5972-1281","authenticated-orcid":false,"given":"Maxine E.","family":"Kresse","sequence":"additional","affiliation":[{"name":"University of Virginia, Virginia, United States","place":["Charlottesville"],"department":["Department of Musculoskeletal Radiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1148\/rg.273065122","article-title":"Imaging manifestations of blastomycosis: a pulmonary infection with potential dissemination","volume":"27","author":"W Fang","year":"2007","journal-title":"Radiographics"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.ccm.2017.04.006","article-title":"Clinical manifestations and treatment of blastomycosis","volume":"38","author":"J A McBride","year":"2017","journal-title":"Clin Chest Med"},{"issue":"28","key":"ref3","first-page":"601","article-title":"Blastomycosis\u2014Wisconsin, 1986-1995","volume":"45","author":"Centers for Disease Control and Prevention (CDC)","year":"1996","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1086\/588300","article-title":"Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America","volume":"46","author":"S W Chapman","year":"2008","journal-title":"Clin Infect Dis"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.sjopt.2018.02.001","article-title":"Blastomyces species and orbital apex syndrome: unsuspected co-infection","volume":"32","author":"J R Safneck","year":"2018","journal-title":"Saudi J Ophthalmol"},{"issue":"12","key":"ref6","first-page":"13","article-title":"Blastomycosis of the central nervous system","volume":"17","author":"A Kazmer","year":"2024","journal-title":"J Radiol Case Rep"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"100754","DOI":"10.1016\/j.mmcr.2025.100754","article-title":"Disseminated cutaneous blastomycosis in a liver transplant recipient: a case report","volume":"50","author":"B Z Sim","year":"2025","journal-title":"Med Mycol Case Rep"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijscr.2015.11.031","article-title":"Fungal osteomyelitis with vertebral re-ossification","volume":"19","author":"D J OGuinn","year":"2016","journal-title":"Int J Surg Case Rep"}],"container-title":["Seminars in Musculoskeletal Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2924-0545.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T09:06:38Z","timestamp":1791363998000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2924-0545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,9]]},"references-count":8,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2026,10,6]]},"published-print":{"date-parts":[[2026,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2924-0545","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1089-7860","1098-898X"],"issn-type":[{"value":"1089-7860","type":"print"},{"value":"1098-898X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,9]]}}}