{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:50:58Z","timestamp":1791244258185,"version":"4.1.0"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Subdural empyema is a neurosurgical emergency traditionally managed with craniotomy and prolonged intravenous antibiotic therapy. Minimally invasive approaches may represent an alternative in selected cases, particularly when combined with timely diagnosis and targeted antimicrobial treatment.<\/jats:p>\n                  <jats:p>We report two cases of subdural empyema treated with minimally invasive burr-hole evacuation.<\/jats:p>\n                  <jats:p>A 22-year-old man with developmental anomalies and postischemic stroke history presented with intermittent high fever for 2 weeks. Rapid neurological deterioration over 24\u2009hours led to coma (Glasgow Coma Scale 5). Cranial computed tomography (CT) revealed a right-sided subdural empyema with significant mass effect. Emergency burr-hole evacuation was performed, followed by broad-spectrum antibiotics later tailored to Staphylococcus aureus.<\/jats:p>\n                  <jats:p>A 40-year-old man presented with hypertensive intracranial syndrome and febrile episodes for 1 week. CT and magnetic resonance imaging revealed a left hemispheric subdural collection suggestive of empyema, likely secondary to otitis media from suspected Streptococcus anginosus. Burr-hole evacuation and empiric triple antibiotic therapy were initiated.<\/jats:p>\n                  <jats:p>In both cases, postoperative imaging confirmed complete evacuation without residual collection. The first patient required prolonged intensive care with gradual neurological improvement over several weeks, whereas the second patient achieved immediate postoperative recovery. At 2-year radiological follow-up, no recurrence was observed in either patient.<\/jats:p>\n                  <jats:p>Minimally invasive burr-hole evacuation, combined with culture-guided antibiotic therapy, can be effective in selected cases of subdural empyema, yielding favorable clinical and radiological outcomes.<\/jats:p>","DOI":"10.1055\/a-2931-1083","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T22:57:31Z","timestamp":1787957851000},"page":"484-489","source":"Crossref","is-referenced-by-count":0,"title":["Mini-Invasive Neurosurgical Treatment of Subdural Empyema: A Two-Patient Case Series"],"prefix":"10.1055","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6394-2377","authenticated-orcid":false,"given":"Ejona Rifat","family":"Isakaj Lilamani","sequence":"additional","affiliation":[{"name":"Service of Neurosciences, Department of Neurosurgery, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2366-6632","authenticated-orcid":false,"given":"Aurora Arben","family":"Mu\u00e7a","sequence":"additional","affiliation":[{"name":"Service of Neurosciences, Department of Neurosurgery, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3365-3430","authenticated-orcid":false,"given":"Arben Jonuz","family":"Rroji","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology and Imaging Service, Service of Neurosciences, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7894-9168","authenticated-orcid":false,"given":"Artid Agron","family":"Lame","sequence":"additional","affiliation":[{"name":"Service of Neurosciences, Department of Neurosurgery, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2800-6618","authenticated-orcid":false,"given":"Arba Firdus","family":"Cecia","sequence":"additional","affiliation":[{"name":"Loyola, University Chicago Stritch School of Medicine, Maywood, Illinois, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4788-9639","authenticated-orcid":false,"given":"Mithat Ismail","family":"Demneri","sequence":"additional","affiliation":[{"name":"Service of Anesthesiology and Reanimation, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9123-2172","authenticated-orcid":false,"given":"Arsen Haki","family":"Seferi","sequence":"additional","affiliation":[{"name":"Service of Neurosciences, Department of Neurosurgery, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ridvan Hamid","family":"Alimehmeti","sequence":"additional","affiliation":[{"name":"Service of Neurosciences, Department of Neurosurgery, University of Medicine Tirana, University Hospital Centre \u201cMother Theresa,\u201d Tirana, Albania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4103\/1793-5482.175630","article-title":"Which should be appropriate surgical treatment for subtentorial epidural empyema? 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