{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:08:36Z","timestamp":1788908916568,"version":"build-2803163510"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Aims: Since type 2 diabetes is one of the greatest burdens in public health over\n                    the past decade, evidence regarding its impact on the Greek population is\n                    scarce. To address this situation, the current study aims to reveal\n                    epidemiological data on type 2 diabetes in Greece by calculating the annual\n                    prevalence between 2016 and 2022 and to investigate trends regarding age and sex\n                    factors.<\/jats:p>\n                  <jats:p>Methods: Real-world prescription data were used from the official database of the\n                    e-Government Center for Social Security Services. The study population comprised\n                    individuals who were entitled to type 2 diabetes care, with the relevant\n                    International Classification of Diseases, 10th Revision code. Descriptive\n                    statistics, chi-square tests and regression analysis were performed by\n                    calculating prevalence rates, using 2011 official census of Greek\n                    population.<\/jats:p>\n                  <jats:p>Results: Prevalence rates of type 2 diabetes follow an increasing trend,\n                    increasing from 7.97% in 2016 to 8.65% in 2022. A similar trend was\n                    observed among male and female individuals; the male prevalence rate\n                    increased from 8% in 2016 to 8.86% in 2022, whereas the female prevalence rate\n                    increased from 7.95% in 2016 to 8.46% in 2022. The prevalence rate ratios\n                    between 2016 and 2022 underline the increasing trends of type 2 diabetes in\n                    population, as the total prevalence rate ratio was equal to 1.09 (95% confidence\n                    interval: 1.08\u20131.09, p\u2009&lt;\u20090.001). Linear regression revealed the\n                    association between the prevalence rate and the sex or age factor.<\/jats:p>\n                  <jats:p>Conclusions: Type 2 diabetes prevalence in Greece increased between 2016 and\n                    2022, in accordance with the European and International data, with higher rates\n                    observed among males and older adults. The marked relative increase among\n                    individuals aged 18 to 29 years constitutes an important epidemiological finding\n                    and highlights the need for targeted prevention and early intervention\n                    strategies.<\/jats:p>","DOI":"10.1055\/a-2937-5128","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:59:21Z","timestamp":1788908361000},"source":"Crossref","is-referenced-by-count":0,"title":["Prevalence and Projection of Medicine-Treated Type 2 Diabetes in\n                    Greece (2016\u20132022): Real-World Data from the National prescription\n                    database"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5555-3522","authenticated-orcid":false,"given":"Spyros","family":"Polyzois","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace School of Health\n                    Sciences, Evros, Greece","place":["Alexandroupoli"],"department":["Laboratory of Hygiene and Enviromental Protection, Department of\n                    Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiota","family":"Mitrou","sequence":"additional","affiliation":[{"name":"Hellenic Ministry of Health, Attica, Greece","place":["Athens"],"department":["Independent Department of Therapeutic Protocols and Patient\n                    Registries"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasios","family":"Tsolakidis","sequence":"additional","affiliation":[{"name":"e-Government Center for Social Security Services (IDIKA), Attica, Greece","place":["Athens"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7320-785X","authenticated-orcid":false,"given":"Nikolaos","family":"Papanas","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace, Greece","place":["Alexandroupolis"],"department":["Second Department of Internal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodoros","family":"Constantinides","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace School of Health\n                    Sciences, Evros, Greece","place":["Alexandroupoli"],"department":["Laboratory of Hygiene and Enviromental Protection, Department of\n                    Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Kontogiorgis","sequence":"additional","affiliation":[{"name":"Democritus University of Thrace School of Health\n                    Sciences, Evros, Greece","place":["Alexandroupoli"],"department":["Laboratory of Hygiene and Enviromental Protection, Department of\n                    Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1016\/S0140-6736(23)01296-5","article-title":"Diabetes: A defining disease of the 21st century","volume":"401","author":"The Lancet","year":"2023","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e2004","DOI":"10.1002\/hsr2.2004","article-title":"Diabetes mellitus, the fastest growing global public health concern: Early\n                    detection should be focused","volume":"7","author":"MdJ Hossain","year":"2024","journal-title":"Health Sci Rep"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1016\/S0140-6736(24)02317-1","article-title":"Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: A\n                    pooled analysis of 1108 population-representative studies with 141 million\n   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Papazoglou","year":"1995","journal-title":"Diabet Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1111\/j.1464-5491.2005.01731.x","article-title":"The epidemiology of type 2 diabetes mellitus in greek adults: The ATTICA\n                    study","volume":"22","author":"D B Panagiotakos","year":"2005","journal-title":"Diabet Med"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1900\/RDS.2016.13.246","article-title":"Dietary patterns and 10-year (2002\u20132012) incidence of type 2 diabetes: Results\n                    from the ATTICA cohort study","volume":"13","author":"E Koloverou","year":"2016","journal-title":"Rev Diabet Stud"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1111\/j.1464-5491.2009.02692.x","article-title":"Prevalence of diabetes mellitus and obesity in the general adult population of\n                    Greece: A door-to-door epidemiological study","volume":"26","author":"N 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