{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:06:02Z","timestamp":1790118362623,"version":"4.0.1"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Prax"],"abstract":"Zusammenfassung<\/jats:title>\n Untersuchung der Verordnungssequenz von Antidementiva und Antipsychotika im\n ersten Jahr nach Erstdiagnose einer Demenz in haus- und fach\u00e4rztlichen\n Praxen Deutschlands.<\/jats:p>\n Retrospektive Kohortenstudie mit Daten der IQVIA Disease Analyzer-Datenbank\n (1.179 Hausarzt-, 214 Facharztpraxen; 2005\u20132024). Eingeschlossen wurden\n Patienten\u226565 Jahre mit Erstdiagnose Demenz ohne Vorverordnung (Hausarzt:\n n=94.036; Facharzt: n=55.341).<\/jats:p>\n In Hausarztpraxen erhielten 54,2% nach Diagnosestellung weder Antidementiva\n noch Antipsychotika, 27,3% ausschlie\u00dflich Antipsychotika, 8,7%\n ausschlie\u00dflich Antidementiva. In Facharztpraxen war der Anteil ohne\n Verordnung geringer (22,2%); h\u00e4ufiger wurde zun\u00e4chst antidementiv behandelt\n (16,0% vs. 5,6%).<\/jats:p>\n Facharztpraxen setzen h\u00e4ufiger leitliniengerecht zun\u00e4chst Antidementiva ein;\n in Hausarztpraxen dominieren antipsychotische Erstverordnungen und\n Therapieverzicht.<\/jats:p>","DOI":"10.1055\/a-2939-0340","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:51:41Z","timestamp":1790117501000},"source":"Crossref","is-referenced-by-count":0,"title":["Reihenfolge der Verordnung von Antidementiva und Antipsychotika nach\n Erstdiagnose einer Demenz in deutschen Hausarzt- und Facharzt-Praxen \u2013 eine\n retrospektive Kohortenstudie"],"prefix":"10.1055","author":[{"given":"Jens","family":"Bohlken","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Sozialmedizin, Arbeitsmedizin und Public Health (ISAP),\n Medizinischen Fakult\u00e4t der Universit\u00e4t Leipzig, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karel","family":"Kostev","sequence":"additional","affiliation":[{"name":"Epidemiology, IQVIA Germany, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(24)01296-0","article-title":"Dementia prevention, intervention, and care: 2024 report of the Lancet standing\n Commission","volume":"404","author":"G Livingston","year":"2024","journal-title":"Lancet"},{"key":"ref3","volume-title":"Dementia: assessment, management and support for people living with dementia and\n their carers. 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\u2013\n Ergebnisse einer qualitativen Studie","volume":"17","author":"J Wangler","year":"2022","journal-title":"Pr\u00e4vention und Gesundheitsf\u00f6rderung"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1177\/13872877251319468","article-title":"Dementia diagnosis and prescription of antidementia drugs: an analysis of German\n claims data (2006\u20132016)","volume":"104","author":"C Becker","year":"2025","journal-title":"J Alzheimers Dis"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"3937","DOI":"10.1097\/JS9.0000000000001381","article-title":"The value of cholinesterase inhibitors for improving neuropsychiatric and\n functional assessment scores in patients with Alzheimer disease: a systematic\n review and meta-analysis of placebo-controlled RCTs","volume":"110","author":"Y Zhang","year":"2024","journal-title":"Int J Surg"},{"key":"ref19","first-page":"CD003154","article-title":"Memantine for dementia","volume":"3","author":"R McShane","year":"2019","journal-title":"Cochrane Database Syst\n Rev"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s13690-025-01626-z","article-title":"Sex and gender differences in access, quality of care, and effectiveness of\n treatment in dementia: a scoping review of studies up to 2024","volume":"83","author":"E Aguzzoli","year":"2025","journal-title":"Arch Public Health"},{"key":"ref21","first-page":"393","article-title":"Inequalities in receipt of mental and physical healthcare in people with\n dementia in the UK","volume":"46","author":"C Cooper","year":"2016","journal-title":"Age Ageing"}],"container-title":["Psychiatrische Praxis"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2939-0340.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:51:44Z","timestamp":1790117504000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2939-0340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,22]]},"references-count":20,"URL":"https:\/\/doi.org\/10.1055\/a-2939-0340","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0303-4259","1439-0876"],"issn-type":[{"value":"0303-4259","type":"print"},{"value":"1439-0876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,22]]}}}