{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:52:34Z","timestamp":1792785154519,"version":"4.5.0"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Bundesministerium f\u00fcr Forschung, Technologie und Raumfahrt","award":["01KX2121"],"award-info":[{"award-number":["01KX2121"]}],"id":[{"id":"https:\/\/ror.org\/04pz7b180","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gesundheitswesen"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>Patient*innen in haus\u00e4rztlichen Praxen sind f\u00fcr eine Teilnahme an klinischen\n                        Studien h\u00e4ufig unzureichend erreichbar. Da ein Gro\u00dfteil der Versorgung\n                        ambulant erfolgt, ist es essenziell, diesen Sektor und insbesondere die\n                        haus\u00e4rztliche Ebene als Dreh- und Angelpunkt bei der Ausgestaltung k\u00fcnftiger\n                        Forschungsinfrastrukturen zu ber\u00fccksichtigen. Die NAPKON (Nationales\n                        Pandemie Kohorten Netzwerk) Therapeutische Interventionsplattform\n                        (NAPKON-TIP) ist ein Projekt des Netzwerks Universit\u00e4tsmedizin und schafft\n                        eine Infrastruktur f\u00fcr klinische Studien unter Einbezug des ambulanten\n                        Sektors.<\/jats:p>\n                  <jats:p>Ziel der Studie ist es, Hindernisse f\u00fcr die Studienrekrutierung von\n                        Patient*innen in haus\u00e4rztlichen Praxen sowie Strategien zu deren \u00dcberwindung\n                        zu identifizieren.<\/jats:p>\n                  <jats:p>Von 12\/2024 bis 02\/2025 erfolgte ein Online-Survey mit Fragen zu\n                        Rekrutierungshindernissen, die Haus\u00e4rzt*innen und Medizinische\n                        Fachangestellte (MFA) bei klinischen Studien wahrnehmen. Der Survey wurde\n                        per E-Mail an allgemeinmedizinische Forschungspraxen der Initiative\n                        Deutscher Forschungspraxennetze \u2013 DEGAM-ForNet versendet. Zur Steigerung der\n                        Teilnahme wurden Erinnerungsmails eingesetzt. Die Fragebogendaten wurden\n                        deskriptiv in SPSS und die Freitextantworten inhaltsanalytisch in MAXQDA\n                        ausgewertet.<\/jats:p>\n                  <jats:p>An der Befragung beteiligten sich 62 Personen. Die R\u00fccklaufquote lag bei\n                        7,2%. Der Gro\u00dfteil der Teilnehmenden waren Haus\u00e4rzt*innen (83,9%), 16,1%\n                        waren MFA. Als h\u00e4ufigste Rekrutierungshindernisse wurden ein hoher\n                        administrativer und zeitlicher Aufwand (88,7%), unzureichende Verg\u00fctung\n                        (58,1%) sowie Personalmangel (56,4%) genannt. Qualitativ inhaltsanalytisch\n                        wurden H\u00fcrden im Studiendesign, etwa durch komplexe Einschlusskriterien,\n                        Barrieren im Praxisteam wie Personalmangel, Hindernisse im Praxisalltag\n                        durch schwer integrierbare Abl\u00e4ufe sowie patientenbezogene Schwierigkeiten\n                        wie \u00dcberforderung mit dem Studienaufwand als Rekrutierungshindernisse\n                        identifiziert. Als L\u00f6sungsans\u00e4tze wurden u.\u2009a. die St\u00e4rkung der Rolle von\n                        Praxisteams und Patient*innen als aktive Forschungspartner im Sinne einer\n                        echten Partizipation, die Schaffung finanzieller und ideeller Anreize sowie\n                        eine vereinfachte, digitale Studienlogistik benannt.<\/jats:p>\n                  <jats:p>Studien sollten an die Bed\u00fcrfnisse der ambulanten Versorgung angepasst und in\n                        enger Zusammenarbeit mit bestehenden Forschungspraxen geplant werden. Dies\n                        kann haus\u00e4rztlichen Praxen die Studienteilnahme erleichtern und die\n                        Grundlage f\u00fcr eine sektoren\u00fcbergreifende Forschungsinfrastruktur schaffen,\n                        in der der ambulante Sektor gleichberechtigt vertreten ist. Bei der\n                        vorliegenden Befragung ist nicht auszuschlie\u00dfen, dass \u00c4rzt*innen und MFA\n                        teilweise in derselben Praxis arbeiteten und die Teilnahme zwischen den\n                        Praxen dadurch nicht ausgewogen war.<\/jats:p>","DOI":"10.1055\/a-2939-7615","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T08:41:50Z","timestamp":1790584910000},"source":"Crossref","is-referenced-by-count":0,"title":["Wie gelingen klinische Studien im haus\u00e4rztlichen Setting \u2013\n                    Herausforderungen und L\u00f6sungsstrategien \u2013 eine Befragung forschungsaktiver\n                    Praxen"],"prefix":"10.1055","author":[{"given":"Stefanie","family":"Joos","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinikum T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Institut f\u00fcr Allgemeinmedizin und Interprofessionelle Versorgung"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ildik\u00f3","family":"G\u00e1gyor","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinikum W\u00fcrzburg, BY, Germany","place":["W\u00fcrzburg"],"department":["Institut f\u00fcr Allgemeinmedizin"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7968-1600","authenticated-orcid":false,"given":"Hanna","family":"Schrader","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum W\u00fcrzburg, BY, Germany","place":["W\u00fcrzburg"],"department":["Institut f\u00fcr Allgemeinmedizin"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Institut f\u00fcr Allgemeinmedizin und Interprofessionelle Versorgung"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7068-2084","authenticated-orcid":false,"given":"Christian","family":"F\u00f6rster","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Institut f\u00fcr Allgemeinmedizin und Interprofessionelle Versorgung"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6016-8140","authenticated-orcid":false,"given":"Lia","family":"Heyl","sequence":"additional","affiliation":[{"name":"Medizinische Hochschule Hannover, NDS, Germany","place":["Hannover"],"department":["Institut f\u00fcr Allgemeinmedizin und Palliativmedizin"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonor","family":"Heinz","sequence":"additional","affiliation":[{"name":"Koordinierungsstelle f\u00fcr die Initiative Deutscher Forschungspraxennetze \u2013 DEGAM-ForNet, BE, Germany","place":["Berlin"],"department":["DEGAM-ForNet"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Haumann","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum T\u00fcbingen, BW, Germany","place":["T\u00fcbingen"],"department":["Institut f\u00fcr Allgemeinmedizin und Interprofessionelle Versorgung"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Blaschke","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsmedizin G\u00f6ttingen, NDS, Germany","place":["G\u00f6ttingen"],"department":["Zentrale Notaufnahme"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Meybohm","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum W\u00fcrzburg, BY, Germany","place":["W\u00fcrzburg"],"department":["Klinik und Poliklinik f\u00fcr An\u00e4sthesiologie, Intensivmedizin, Notfallmedizin und Schmerztherapie"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"w20221","DOI":"10.4414\/smw.2020.20221","article-title":"The ecology of medical care in Switzerland: prevalence of illness in the\n                    community and healthcare utilisation in Switzerland","volume":"150","author":"S Giezendanner","year":"2020","journal-title":"Swiss Med Wkly"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"244","DOI":"10.3109\/13814788.2010.528385","article-title":"Series: The research agenda for general practice\/family medicine and primary\n                    health care in Europe. 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