{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:37:52Z","timestamp":1792712272002,"version":"4.5.0"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This retrospective single-center study evaluated the effectiveness and safety of the SOFIA Catheter for percutaneous aspiration thrombectomy (PAT) in periinterventional distal embolization (DE) during lower limb endovascular revascularization.<\/jats:p>\n                  <jats:p>The radiological information system was retrospectively reviewed for all DEs treated with the SOFIA Catheter between 2017 and 2024. Angiographic findings, vessel diameters, embolic origin, technical success, and complications were assessed. Reperfusion was graded using the Peripheral Arterial Reperfusion Score (PARS). PARS 2\u20133 was defined as the primary endpoint (angiographic technical success); conversion of PARS 1 to PARS 2\u20133 after adjunctive therapy as secondary success.<\/jats:p>\n                  <jats:p>A total of 128 vessels in 104 patients (67 male; median age 69 years) were included. Emboli originated from acute lesions in 52% and chronic disease in 48%; in-stent restenosis was present in 17%. Primary angiographic success (PARS 2\u20133) was achieved in 81% (95% CI: 72.8\u201386.4%). After additional PTA or stenting, overall secondary success increased to 88% (95% CI: 80.7\u201392.2%). Thrombectomy failed in 12%. One patient required major amputation and one surgical embolectomy. No catheter-related dissections or perforations occurred. Prior AngioJet use showed an exploratory correlation with PARS 0 (r = 0.329; p &lt; .001).<\/jats:p>\n                  <jats:p>PAT using the SOFIA Catheter demonstrates high angiographic success rates and a favorable safety profile for periinterventional DE in lower limb arteries. Prior hydrodynamic thrombectomy may reduce embolus retrievability; this finding is exploratory and should be considered hypothesis-generating.<\/jats:p>","DOI":"10.1055\/a-2942-7381","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:41:47Z","timestamp":1792708907000},"source":"Crossref","is-referenced-by-count":0,"title":["Percutaneous Aspiration Thrombectomy with the SOFIA Catheter for Periinterventional Distal Embolization in Lower Limb Revascularization"],"prefix":"10.1055","author":[{"given":"Jens","family":"Trentmann","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schekeb","family":"Aludin","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Andersson","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Mostafa","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan-Christoph","family":"Backhauss","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannes","family":"Gottschalk","sequence":"additional","affiliation":[{"name":"University Hospital Schleswig-Holstein - Campus Kiel, Germany","place":["Kiel"],"department":["Clinic for Radiology and Neuroradiology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1177\/1538574418764050","article-title":"Current Status of Distal Embolization in Femoropopliteal Endovascular Interventions","volume":"52","author":"A Cannavale","year":"2018","journal-title":"Vasc Endovascular Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1016\/j.jvs.2007.07.058","article-title":"Incidence and clinical significance of distal embolization during percutaneous interventions involving the superficial femoral artery","volume":"46","author":"RC Lam","year":"2007","journal-title":"J Vasc Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jvs.2017.01.032","article-title":"Distal embolization during lower extremity endovascular interventions","volume":"66","author":"CI Ochoa Chaar","year":"2017","journal-title":"J Vasc Surg"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.jvs.2013.07.119","article-title":"Clinical significance of embolic events in patients undergoing endovascular femoropopliteal interventions with or without embolic protection devices","volume":"59","author":"BC Mendes","year":"2014","journal-title":"J Vasc Surg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1007\/s00270-014-0876-3","article-title":"Standards of practice for superficial femoral and popliteal artery angioplasty and stenting","volume":"37","author":"K Katsanos","year":"2014","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s00270-014-0857-6","article-title":"Percutaneous aspiration thrombectomy for the treatment of arterial thromboembolic occlusions following percutaneous transluminal angioplasty","volume":"38","author":"S Schleder","year":"2015","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1055\/a-1652-1726","article-title":"Percutaneous Aspiration Thrombectomy for Arterial Thromboembolic Occlusion Following Percutaneous Transluminal Angioplasty: Technical Success Rates and Clinical Outcomes","volume":"194","author":"A Schicho","year":"2022","journal-title":"Rofo"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1024\/0301-1526\/a000877","article-title":"Distal embolization during percutaneous revascularization of the lower extremity arteries","volume":"49","author":"A Boc","year":"2020","journal-title":"Vasa"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1136\/jnis-2024-021811","article-title":"SOFIA Aspiration System as first-line Technique (SOFAST): a prospective, multicenter study to assess the efficacy and safety of the 6 French SOFIA Flow Plus aspiration catheter for endovascular stroke thrombectomy","volume":"17","author":"D Gandhi","year":"2025","journal-title":"J Neurointerv Surg"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1441810","DOI":"10.3389\/fneur.2024.1441810","article-title":"Safety and effectiveness of SOFIA\/SOFIA PLUS for direct aspiration as first line treatment in patients with acute anterior ischemic stroke: results from the prospective, multicentric SESAME study","volume":"15","author":"U Neuberger","year":"2024","journal-title":"Front Neurol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00270-024-03876-2","article-title":"Cirse Classification System for Complications v1.1","volume":"48","author":"D Filippiadis","year":"2025","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.jvs.2010.09.008","article-title":"Lesion types and device characteristics that predict distal embolization during percutaneous lower extremity interventions","volume":"53","author":"GV Shrikhande","year":"2011","journal-title":"J Vasc Surg"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1093\/neuros\/nyab366","article-title":"Thrombus Histology as It Relates to Mechanical Thrombectomy: A Meta-Analysis and Systematic Review","volume":"89","author":"A Bhambri","year":"2021","journal-title":"Neurosurgery"},{"key":"ref14","first-page":"7","article-title":"Analysis of particulate debris after superficial femoral artery atherectomy","volume":"21","author":"KA Kaid","year":"2009","journal-title":"J Invasive Cardiol"}],"container-title":["R\u00f6Fo - 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