{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:27:07Z","timestamp":1789658827724,"version":"4.0.1"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","funder":[{"name":"NIDA","award":["R01 DA059393"],"award-info":[{"award-number":["R01 DA059393"]}]},{"name":"Swiss National Science Foundation","award":["225404"],"award-info":[{"award-number":["225404"]}],"id":[{"id":"https:\/\/ror.org\/00yjd3n13","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Synthesis"],"abstract":"<jats:title>Abstract<\/jats:title>","DOI":"10.1055\/a-2945-3974","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T22:46:27Z","timestamp":1788302787000},"source":"Crossref","is-referenced-by-count":0,"title":["Synthesis and Biological Evaluation of O6C-Salvinorin Alkyne Probes"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9809-6343","authenticated-orcid":false,"given":"Etienne","family":"Cotter","sequence":"additional","affiliation":[{"name":"Scripps Research, California, United States","place":["La Jolla"],"department":["Department of Chemistry"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Leoni","sequence":"additional","affiliation":[{"name":"Scripps Research, California, United States","place":["La Jolla"],"department":["Department of Chemistry"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Dao","sequence":"additional","affiliation":[{"name":"Scripps Research, California, United States","place":["La Jolla"],"department":["Department of Chemistry"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Jane","family":"Hill","sequence":"additional","affiliation":[{"name":"Scripps Research, California, United States","place":["La Jolla"],"department":["Department of Chemistry"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Faragher","sequence":"additional","affiliation":[{"name":"University of South Florida, United States","place":["Tampa"],"department":["Department of Molecular Pharmacology and Physiology Morsani College of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vuong Q","family":"Dang","sequence":"additional","affiliation":[{"name":"University of South Florida, United States","place":["Tampa"],"department":["Department of Molecular Pharmacology and Physiology Morsani College of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura M","family":"Bohn","sequence":"additional","affiliation":[{"name":"University of South Florida, United States","place":["Tampa"],"department":["Department of Molecular Pharmacology and Physiology Morsani College of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8353-6449","authenticated-orcid":false,"given":"Ryan A.","family":"Shenvi","sequence":"additional","affiliation":[{"name":"Scripps Research, California, United States","place":["La Jolla"],"department":["Department of Chemistry"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/s41586-023-06030-7","volume":"617","author":"J Han","year":"2023","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-026-73615-x","author":"Y Zhao","year":"2026","journal-title":"Nat Commun"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.bmcl.2018.03.029","volume":"28","author":"J J Roach","year":"2018","journal-title":"Bioorg Med Chem Lett"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1021\/acsmedchemlett.7b00224","volume":"8","author":"L M Bohn","year":"2017","journal-title":"ACS Med Chem Lett"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"eaar4309","DOI":"10.1126\/scisignal.aar4309","volume":"11","author":"J-H Ho","year":"2018","journal-title":"Sci Signal"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1016\/j.cell.2022.03.040","volume":"185","author":"Z Pang","year":"2022","journal-title":"Cell"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1021\/acscentsci.7b00488","volume":"3","author":"J J Roach","year":"2017","journal-title":"ACS Cent Sci"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1016\/j.bmcl.2018.01.055","volume":"28","author":"S Hirasawa","year":"2018","journal-title":"Bioorg Med Chem Lett"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1021\/acscentsci.3c00616","volume":"9","author":"S J Hill","year":"2023","journal-title":"ACS Cent Sci"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1021\/ja800103z","volume":"130","author":"S Son","year":"2008","journal-title":"J Am Chem Soc"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"14723","DOI":"10.1021\/acs.joc.8b02201","volume":"83","author":"T J Fulton","year":"2018","journal-title":"J Org Chem"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"7718","DOI":"10.1021\/ja001260j","volume":"122","author":"R S Miller","year":"2000","journal-title":"J Am Chem Soc"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"9155","DOI":"10.1039\/c3cs60223k","volume":"42","author":"M Szostak","year":"2013","journal-title":"Chem Soc Rev"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.26434\/chemrxiv.15006115\/v1","author":"E Cotter","year":"2026","journal-title":"ChemRxiv"}],"container-title":["Synthesis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2945-3974.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:45:44Z","timestamp":1789512344000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2945-3974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":14,"URL":"https:\/\/doi.org\/10.1055\/a-2945-3974","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0039-7881","1437-210X"],"issn-type":[{"value":"0039-7881","type":"print"},{"value":"1437-210X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9,1]]},"published":{"date-parts":[[2026,9,1]]}}}