{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:41:33Z","timestamp":1792194093189,"version":"4.4.0"},"reference-count":43,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>De-Prescribing beschreibt den Prozess der Pharmakotherapieoptimierung durch\n                    Dosisreduktion oder Beendigung von Medikamenten. Aufgrund der hohen\n                    Polypharmazieraten ist das De-Prescribing im Bereich der Gerontopsychiatrie von\n                    hoher klinischer Relevanz. Die Reduktion psychotroper Medikamente ist in der\n                    Mehrzahl der F\u00e4lle m\u00f6glich und tr\u00e4gt zu einer Verbesserung der Lebensqualit\u00e4t\n                    bei. Eine Orientierung beim De-Prescribing bieten Listen potentiell inad\u00e4quater\n                    Medikamente (PIM), Leitlinien und spezifische De-Prescribing-Tools, wobei die\n                    erforderliche Risiko-Nutzen-Analyse und Einzelfallbetrachtung nicht ersetzbar\n                    ist. Essentielle Voraussetzung f\u00fcr ein gelingendes De-Prescribing ist eine\n                    transparente Kommunikation mit Patienten und Angeh\u00f6rigen \u00fcber Nutzen und Risiken\n                    und die individuelle Abw\u00e4gung. Diese Arbeit fasst verf\u00fcgbare\n                    De-Prescribingempfehlungen aus Leitlinien, PIM-Listen und De-Prescribing-Tools\n                    f\u00fcr den Bereich der Gerontopsychiatrie zusammen.<\/jats:p>","DOI":"10.1055\/a-2946-3364","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:53:45Z","timestamp":1792191225000},"source":"Crossref","is-referenced-by-count":0,"title":["De-Prescribing in der Gerontopsychiatrie \u2013 \u00dcbersicht zu\n                    Leitlinienempfehlungen, De-Prescribing- Algorithmen und Tools"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2936-5180","authenticated-orcid":false,"given":"Robert","family":"Haussmann","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Carl Gustav Carus, Sachsen, Germany","place":["Dresden"],"department":["Klinik und Poliklinik f\u00fcr Psychiatrie und Psychotherapie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Borchers","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Carl Gustav Carus, SN, Germany","place":["Dresden"],"department":["Klinikapotheke"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e287","DOI":"10.1016\/S2666-7568(24)00007-2","article-title":"Prevalence of multimorbidity and polypharmacy among adults and older adults: a\n                    systematic review","volume":"5","author":"K Nicholson","year":"2024","journal-title":"Lancet Healthy Longev"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2357232","DOI":"10.1080\/07853890.2024.2357232","article-title":"Polypharmacy and potentially inappropriate prescribing of\n                    benzodiazepines in older nursing home 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